ID   Mero-25
AC   CVCL_2591
SY   MERO25
DR   cancercelllines; CVCL_2591
DR   Cell_Model_Passport; SIDM01788
DR   DepMap; ACH-001556
DR   ECACC; 09100102
DR   FANTOM5_SSTAR; 10850-111F4
DR   Wikidata; Q54905205
RX   PubMed=2474517;
RX   PubMed=2790740;
RX   PubMed=25902174;
RX   PubMed=33567673;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: ~48 hours (PubMed=2474517).
CC   Transformant: ChEBI; CHEBI_46661; Asbestos.
CC   Omics: Genomics; Whole exome sequencing.
CC   Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977.
ST   Source(s): DepMap=ACH-001556; ECACC=09100102
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 12
ST   D16S539: 11,12
ST   D18S51: 18
ST   D21S11: 30,31
ST   D3S1358: 15
ST   D5S818: 11,12
ST   D7S820: 9
ST   D8S1179: 13
ST   FGA: 21
ST   Penta D: 9,13
ST   Penta E: 7,16
ST   TH01: 8
ST   TPOX: 9
ST   vWA: 16,17
DI   NCIt; C45665; Pleural biphasic mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   >60Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 22
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RX   PubMed=2474517; DOI=10.1002/ijc.2910440212;
RA   Versnel M.A., Bouts M.J., Hoogsteden H.C., van der Kwast T.H.,
RA   Delahaye M., Hagemeijer A.;
RT   "Establishment of human malignant mesothelioma cell lines.";
RL   Int. J. Cancer 44:256-260(1989).
//
RX   PubMed=2790740; DOI=10.1016/0165-4608(89)90014-9;
RA   Versnel M.A., Hoogsteden H.C., Hagemeijer A., Bouts M.J.,
RA   van der Kwast T.H., Delahaye M., Schaart G., Ramaekers F.C.S.;
RT   "Characterization of three human malignant mesothelioma cell lines.";
RL   Cancer Genet. Cytogenet. 42:115-128(1989).
//
RX   PubMed=25902174; DOI=10.1097/JTO.0000000000000493;
RA   Miyanaga A., Masuda M., Tsuta K., Kawasaki K., Nakamura Y., Sakuma T.,
RA   Asamura H., Gemma A., Yamada T.;
RT   "Hippo pathway gene mutations in malignant mesothelioma: revealed by
RT   RNA and targeted exon sequencing.";
RL   J. Thorac. Oncol. 10:844-851(2015).
//
RX   PubMed=33567673; DOI=10.3390/cancers13040685; PMCID=PMC7915464;
RA   Keller M., Reis K., Hjerpe A., Dobra K., Aspenstrom P.;
RT   "Cytoskeletal organization correlates to motility and invasiveness of
RT   malignant mesothelioma cells.";
RL   Cancers (Basel) 13:685.1-685.20(2021).
//