ID   HS-Sultan
AC   CVCL_2516
SY   Hs-Sultan; HS-SULTAN; HS-sultan; HS Sultan; HSSultan; H. S. Sultan; SULTAN; Sultan
DR   BTO; BTO:0003035
DR   CLO; CLO_0004264
DR   EFO; EFO_0002199
DR   CLDB; cl1723
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-2706
DR   ATCC; CRL-1484
DR   BioSample; SAMN03151805
DR   cancercelllines; CVCL_2516
DR   Cosmic; 759913
DR   Cosmic; 846385
DR   ECACC; 87012701
DR   EGA; EGAS00001000610
DR   IARC_TP53; 27008
DR   IGRhCellID; HSSultan
DR   JCRB; JCRB9062
DR   LINCS_LDP; LCL-2036
DR   PharmacoDB; HSSultan_616_2019
DR   Progenetix; CVCL_2516
DR   Wikidata; Q54896292
RX   DOI=10.1007/0-306-46877-8_4;
RX   PubMed=4549735;
RX   PubMed=6365856;
RX   PubMed=10516762;
RX   PubMed=11021758;
RX   PubMed=12592342;
RX   PubMed=19220422;
RX   PubMed=20143388;
RX   PubMed=20215515;
RX   PubMed=25485619;
RX   PubMed=26589293;
RX   PubMed=29892436;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a Jiyoye derivative (PubMed=10516762; PubMed=12592342; PubMed=20143388). Originally thought to originate from a plasma cell myeloma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00214.
CC   Population: African; Nigerian.
CC   Doubling time: 24 hours (PubMed=6365856).
CC   HLA typing: A*03:01,74:01; B*53:01,58:01; C*04:01,04:01 (PubMed=26589293).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys132Gln (c.394A>C); ClinVar=VCV000376628; Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): ATCC=CRL-1484; ECACC=87012701; JCRB=JCRB9062
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 12
ST   D16S539: 10,11
ST   D18S51: 12,19
ST   D19S433: 12,15
ST   D21S11: 28,36
ST   D2S1338: 21
ST   D3S1358: 16,17
ST   D5S818: 12
ST   D7S820: 8,10
ST   D8S1179: 14,15
ST   FGA: 23,24
ST   Penta D: 2.2,12
ST   Penta E: 8,12
ST   TH01: 7,9
ST   TPOX: 6,8
ST   vWA: 15,19
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1317 ! Jiyoye
SX   Male
AG   7Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 33
//
RX   DOI=10.1007/0-306-46877-8_4;
RA   Jernberg-Wiklund H., Nilsson K.;
RT   "Multiple myeloma cell lines.";
RL   (In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000).
//
RX   PubMed=4549735; DOI=10.1038/250507a0;
RA   Harris N.S.;
RT   "Plasma cell surface antigen on human blood lymphocytes.";
RL   Nature 250:507-509(1974).
//
RX   PubMed=6365856; DOI=10.1016/0198-8859(84)90041-7;
RA   Schwaber J.F., Posner M.R., Schlossman S.F., Lazarus H.;
RT   "Human-human hybrids secreting pneumococcal antibodies.";
RL   Hum. Immunol. 9:137-143(1984).
//
RX   PubMed=10516762; DOI=10.1038/sj.leu.2401510;
RA   Drexler H.G., Dirks W.G., MacLeod R.A.F.;
RT   "False human hematopoietic cell lines: cross-contaminations and
RT   misinterpretations.";
RL   Leukemia 13:1601-1607(1999).
//
RX   PubMed=11021758; DOI=10.1038/sj.leu.2401891;
RA   Majka M., Rozmyslowicz T., Honczarenko M.J., Ratajczak J., Wasik M.A.,
RA   Gaulton G.N., Ratajczak M.Z.;
RT   "Biological significance of the expression of HIV-related chemokine
RT   coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic
RT   cell lines.";
RL   Leukemia 14:1821-1832(2000).
//
RX   PubMed=12592342; DOI=10.1038/sj.leu.2402799;
RA   Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.;
RT   "False leukemia-lymphoma cell lines: an update on over 500 cell
RT   lines.";
RL   Leukemia 17:416-426(2003).
//
RX   PubMed=19220422; DOI=10.1111/j.1600-0609.2009.01211.x;
RA   Kamihira S., Terada C., Sasaki D., Yanagihara K., Tsukasaki K.,
RA   Hasegawa H., Yamada Y.;
RT   "Aberrant p53 protein expression and function in a panel of
RT   hematopoietic cell lines with different p53 mutations.";
RL   Eur. J. Haematol. 82:301-307(2009).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S.,
RA   Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G.,
RA   Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J.,
RA   Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L.,
RA   Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J.,
RA   Settleman J., Seshagiri S., Zhang Z.-M.;
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P.,
RA   Loewer M., Sahin U., Castle J.C.;
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=29892436; DOI=10.1098/rsos.172472; PMCID=PMC5990783;
RA   Shioda S., Kasai F., Watanabe K., Kawakami K., Ohtani A., Iemura M.,
RA   Ozawa M., Arakawa A., Hirayama N., Kawaguchi E., Tano T., Miyata S.,
RA   Satoh M., Shimizu N., Kohara A.;
RT   "Screening for 15 pathogenic viruses in human cell lines registered at
RT   the JCRB Cell Bank: characterization of in vitro human cells by viral
RT   infection.";
RL   R. Soc. Open Sci. 5:172472-172472(2018).
//