ID   HRA-19a1.1 Alpha2 F
AC   CVCL_2513
SY   HRA-19a1.1 Alpha 2F
DR   cancercelllines; CVCL_2513
DR   ECACC; 09071520
DR   Wikidata; Q54895217
DR   Ximbio; 152469
RX   PubMed=18664572;
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Arg405Ter (c.1213C>T); ClinVar=VCV000127275; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Arg1450Ter (c.4348C>T); ClinVar=VCV000194585; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 914; B2M; Simple; p.Ser16Alafs*27 (c.42_45delTCTT); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: HGNC; 6137; ITGA2.
CC   Discontinued: Ximbio; 152469; probable.
CC   Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
ST   Source(s): ECACC=09071520
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 11
ST   D5S818: 11
ST   D7S820: 9,12
ST   TH01: 8
ST   TPOX: 11
ST   vWA: 16
DI   NCIt; C9383; Rectal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2509 ! HRA-19a1.1
SX   Male
AG   66Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 19
//
RX   PubMed=18664572; DOI=10.1074/jbc.M802932200;
RA   Kirkland S.C., Ying H.-J.;
RT   "Alpha2beta1 integrin regulates lineage commitment in multipotent
RT   human colorectal cancer cells.";
RL   J. Biol. Chem. 283:27612-27619(2008).
//