ID   HRA-19a1.1
AC   CVCL_2509
DR   cancercelllines; CVCL_2509
DR   ECACC; 09071517
DR   Wikidata; Q54895215
DR   Ximbio; 152466
RX   PubMed=2449944;
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Arg405Ter (c.1213C>T); ClinVar=VCV000127275; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Arg1450Ter (c.4348C>T); ClinVar=VCV000194585; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:914; B2M; Simple; p.Ser16Alafs*27 (c.42_45delTCTT); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Discontinued: Ximbio; 152466; probable.
CC   Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
ST   Source(s): ECACC=09071517
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 11
ST   D5S818: 11
ST   D7S820: 9,12
ST   TH01: 8
ST   TPOX: 11
ST   vWA: 16
DI   NCIt; C9383; Rectal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2508 ! HRA-19
SX   Male
AG   66Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 20
CH   CVCL_2512 ! HRA-19a1.1 Alpha2 B
CH   CVCL_2513 ! HRA-19a1.1 Alpha2 F
CH   CVCL_2510 ! HRA-19a1.1 Alpha2Alpha1 B
CH   CVCL_2511 ! HRA-19a1.1 Alpha2Alpha1 E
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RX   PubMed=2449944; DOI=10.1002/1097-0142(19880401)61:7<1359::AID-CNCR2820610714>3.0.CO;2-0;
RA   Kirkland, Susan C.
RT   "Clonal origin of columnar, mucous, and endocrine cell lineages in
RT   human colorectal epithelium.";
RL   Cancer 61:1359-1363(1988).
//