ID   HR5
AC   CVCL_2505
SY   HeLa rtTA HR5; HeLa HR5
DR   CLO; CLO_0003834
DR   CLDB; cl1708
DR   BioSample; SAMN03470982
DR   ECACC; 95091409
DR   Wikidata; Q54895210
RX   PubMed=7792603;
RX   PubMed=25877200;
CC   Population: African American.
CC   Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 9,10,11
ST   D13S317: 12,13.3
ST   D16S539: 9,10,13
ST   D18S51: 13,16
ST   D19S433: 13,14,16
ST   D21S11: 27,29
ST   D2S1338: 17
ST   D3S1358: 15,16,18
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   D8S1179: 12
ST   FGA: 18,21
ST   Penta D: 8
ST   Penta E: 7,17
ST   TH01: 7
ST   TPOX: 12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 19
//
RX   PubMed=7792603; DOI=10.1126/science.7792603;
RA   Gossen M., Freundlieb S., Bender G., Muller G., Hillen W., Bujard H.;
RT   "Transcriptional activation by tetracyclines in mammalian cells.";
RL   Science 268:1766-1769(1995).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//