ID   HL60 Ast.3
AC   CVCL_2495
SY   HL60 Ast 3; HL60 Ast3
DR   CLO; CLO_0003777
DR   CLDB; cl1695
DR   cancercelllines; CVCL_2495
DR   ECACC; 88120801
DR   Wikidata; Q54889826
RX   PubMed=3165665;
RX   PubMed=6641827;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCIt; C129638; Astatine-211 alpha radiation.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): ECACC=88120801
ST   Amelogenin: X
ST   CSF1PO: 14
ST   D13S317: 8,11
ST   D16S539: 11
ST   D5S818: 12
ST   D7S820: 11,12
ST   TH01: 7
ST   TPOX: 8,11
ST   vWA: 16
DI   NCIt; C7961; Adult acute myeloid leukemia with maturation
DI   ORDO; Orphanet_98834; Acute myeloblastic leukemia with maturation
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0002 ! HL-60
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 26
//
RX   PubMed=6641827;
RA   Bunce, Christopher M.
RA   Fisher, Amanda Gay
RA   Toksoz, Deniz
RA   Brown, Geoffrey
RT   "Isolation and characterisation of dimethylsulphoxide resistant
RT   variants from the human promyeloid cell line HL60.";
RL   Exp. Hematol. 11:828-833(1983).
//
RX   PubMed=3165665; DOI=10.1038/bjc.1988.128; PMCID=PMC2246464;
RA   Bunce, Christopher M.
RA   Lord, Janet Mary
RA   Wong, A.K.-Y.
RA   Brown, Geoffrey
RT   "Near neighbour analysis of variant cell lines derived from the
RT   promyeloid cell line HL60.";
RL   Br. J. Cancer 57:559-563(1988).
//