ID   H33HJ-JA1
AC   CVCL_2461
DR   CLO; CLO_0003593
DR   CLDB; cl1542
DR   ATCC; CRL-8163
DR   BioSample; SAMN03471197
DR   cancercelllines; CVCL_2461
DR   CCRID; 5301HUM-KCB16015YJ
DR   Cosmic; 683537
DR   ECACC; 90112119
DR   GEO; GSM827363
DR   IARC_TP53; 21354
DR   KCB; KCB 2016015YJ
DR   LINCS_LDP; LCL-2037
DR   Progenetix; CVCL_2461
DR   Wikidata; Q54872070
RX   Patent=US5597901;
RX   PubMed=7592872;
RX   PubMed=20215515;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8163.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
CC   Omics: Variations; SNP array analysis.
CC   Misspelling: H33Hj-A1; KCB=KCB 2016015YJ.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): ATCC=CRL-8163
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 8,10,11
ST   D16S539: 11,12
ST   D5S818: 9
ST   D7S820: 8,10
ST   TH01: 6,9.3
ST   TPOX: 8,10
ST   vWA: 18,19
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0065 ! Jurkat
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 29
//
RX   Patent=US5597901;
RA   Stern, Alvin S.
RT   "Homogeneous human interleukin 2.";
RL   Patent number US5597901, 28-Jan-1997.
//
RX   PubMed=7592872; DOI=10.1074/jbc.270.44.26533;
RA   Fargnoli, Joseph
RA   Burkhardt, Anne L.
RA   Laverty, Maureen
RA   Kut, Stephanie A.
RA   van Oers, Nicolai S.C.
RA   Weiss, Arthur
RA   Bolen, Joseph B.
RT   "Syk mutation in Jurkat E6-derived clones results in lack of p72syk
RT   expression.";
RL   J. Biol. Chem. 270:26533-26537(1995).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//