ID   H33HJ-JA1
AC   CVCL_2461
DR   CLO; CLO_0003593
DR   CLDB; cl1542
DR   ATCC; CRL-8163
DR   BioSample; SAMN03471197
DR   cancercelllines; CVCL_2461
DR   CCRID; 5301HUM-KCB16015YJ
DR   Cosmic; 683537
DR   ECACC; 90112119
DR   GEO; GSM827363
DR   IARC_TP53; 21354
DR   KCB; KCB 2016015YJ
DR   LINCS_LDP; LCL-2037
DR   Progenetix; CVCL_2461
DR   Wikidata; Q54872070
RX   Patent=US5597901;
RX   PubMed=7592872;
RX   PubMed=20215515;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8163.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
CC   Omics: SNP array analysis.
CC   Misspelling: H33Hj-A1; KCB=KCB 2016015YJ.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): ATCC=CRL-8163
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 8,10,11
ST   D16S539: 11,12
ST   D5S818: 9
ST   D7S820: 8,10
ST   TH01: 6,9.3
ST   TPOX: 8,10
ST   vWA: 18,19
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0065 ! Jurkat
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 27
//
RX   Patent=US5597901;
RA   Stern A.S.;
RT   "Homogeneous human interleukin 2.";
RL   Patent number US5597901, 28-Jan-1997.
//
RX   PubMed=7592872; DOI=10.1074/jbc.270.44.26533;
RA   Fargnoli J., Burkhardt A.L., Laverty M., Kut S.A., van Oers N.S.C.,
RA   Weiss A., Bolen J.B.;
RT   "Syk mutation in Jurkat E6-derived clones results in lack of p72syk
RT   expression.";
RL   J. Biol. Chem. 270:26533-26537(1995).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//