ID   h1RPE7
AC   CVCL_2459
SY   h1RPE-7
DR   ECACC; 09061602
DR   Wikidata; Q54871994
RX   PubMed=11504951;
RX   PubMed=11818403;
RX   PubMed=25177495;
CC   Doubling time: ~24 hours (ECACC=09061602).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
CC   Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
ST   Source(s): ECACC=09061602
ST   Amelogenin: X
ST   CSF1PO: 10,13
ST   D13S317: 12
ST   D16S539: 12
ST   D5S818: 9,13
ST   D7S820: 9,10
ST   TH01: 7,9.3
ST   TPOX: 8
ST   vWA: 16,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_9W31 ! h1RPE116
SX   Female
AG   50Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 18
//
RX   PubMed=25177495; DOI=10.1155/2014/801787; PMCID=PMC4142280;
RA   Kuznetsova, Alla V.
RA   Kurinov, Alexander M.
RA   Aleksandrova, Maria A.
RT   "Cell models to study regulation of cell transformation in pathologies
RT   of retinal pigment epithelium.";
RL   J. Ophthalmol. 2014:801787.1-801787.18(2014).
//
RX   PubMed=11818403;
RA   Kanuga, Naheed
RA   Winton, Helen L.
RA   Beauchene, Laurence
RA   Koman, Ahmet
RA   Zerbib, Anne
RA   Halford, Stephanie
RA   Couraud, Pierre-Olivier
RA   Keegan, David J.
RA   Coffey, Peter J.
RA   Lund, Raymond Douglas
RA   Adamson, Peter
RA   Greenwood, John
RT   "Characterization of genetically modified human retinal pigment
RT   epithelial cells developed for in vitro and transplantation studies.";
RL   Invest. Ophthalmol. Vis. Sci. 43:546-555(2002).
//
RX   PubMed=11504951; DOI=10.1073/pnas.171266298; PMCID=PMC55557;
RA   Lund, Raymond Douglas
RA   Adamson, Peter
RA   Sauve, Yves
RA   Keegan, David J.
RA   Girman, Sergej V.
RA   Wang, Shao-Mei
RA   Winton, Helen L.
RA   Kanuga, Naheed
RA   Kwan, Anthony S.L.
RA   Beauchene, Laurence
RA   Zerbib, Anne
RA   Hetherington, Len
RA   Couraud, Pierre-Olivier
RA   Coffey, Peter J.
RA   Greenwood, John
RT   "Subretinal transplantation of genetically modified human cell lines
RT   attenuates loss of visual function in dystrophic rats.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9942-9947(2001).
//