ID   HeLa BU-25
AC   CVCL_2320
SY   HeLa (BU-25); HeLa BU25; HeLa Bu25; HeLa/BU-25; HeLa(BU25); HeLa TK- (BU 25); Bu25 TK-; BU25 TK-; Bu25TK-
DR   CLO; CLO_0002050
DR   CLO; CLO_0050929
DR   CLDB; cl506
DR   cancercelllines; CVCL_2320
DR   Cosmic; 753537
DR   ECACC; 85022104
DR   GEO; GSM827315
DR   Progenetix; CVCL_2320
DR   RCB; RCB0205
DR   Wikidata; Q54882520
RX   PubMed=4639815;
RX   PubMed=5902315;
RX   PubMed=20215515;
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI:472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: SNP array analysis.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): ECACC=85022104; RCB=RCB0205
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 14
ST   D16S539: 9,10
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0058 ! HeLa S3
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 19
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RX   PubMed=4639815; DOI=10.1016/0006-291X(72)90519-0;
RA   Kit S., Kaplan L.A., Leung W.-C., Trkula D.;
RT   "Mitochondrial thymidine kinase of bromodeoxyuridine-resistant,
RT   kinase-deficient HeLa(BU25) cells.";
RL   Biochem. Biophys. Res. Commun. 49:1561-1567(1972).
//
RX   PubMed=5902315; DOI=10.1002/ijc.2910010105;
RA   Kit S., Dubbs D.R., Frearson P.M.;
RT   "HeLa cells resistant to bromodeoxyuridine and deficient in thymidine
RT   kinase activity.";
RL   Int. J. Cancer 1:19-30(1966).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//