ID   HeLa BU-25
AC   CVCL_2320
SY   HeLa (BU-25); HeLa BU25; HeLa Bu25; HeLa/BU-25; HeLa(BU25); HeLa TK- (BU 25); Bu25 TK-; BU25 TK-; Bu25TK-
DR   CLO; CLO_0002050
DR   CLO; CLO_0050929
DR   CLDB; cl506
DR   cancercelllines; CVCL_2320
DR   Cosmic; 753537
DR   ECACC; 85022104
DR   GEO; GSM827315
DR   Progenetix; CVCL_2320
DR   RCB; RCB0205
DR   Wikidata; Q54882520
RX   PubMed=4639815;
RX   PubMed=5902315;
RX   PubMed=20215515;
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI_472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): ECACC=85022104; RCB=RCB0205
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 14
ST   D16S539: 9,10
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0058 ! HeLa S3
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 21
//
RX   PubMed=4639815; DOI=10.1016/0006-291X(72)90519-0;
RA   Kit, Saul
RA   Kaplan, Lawrence A.
RA   Leung, Wai-Choi
RA   Trkula, David
RT   "Mitochondrial thymidine kinase of bromodeoxyuridine-resistant,
RT   kinase-deficient HeLa(BU25) cells.";
RL   Biochem. Biophys. Res. Commun. 49:1561-1567(1972).
//
RX   PubMed=5902315; DOI=10.1002/ijc.2910010105;
RA   Kit, Saul
RA   Dubbs, Del Rose
RA   Frearson, Peter M.
RT   "HeLa cells resistant to bromodeoxyuridine and deficient in thymidine
RT   kinase activity.";
RL   Int. J. Cancer 1:19-30(1966).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//