ID   149BR
AC   CVCL_2271
SY   149 BRighton
DR   CLO; CLO_0001094
DR   CLDB; cl12
DR   ECACC; 90011807
DR   Wikidata; Q54581941
RX   PubMed=1372096;
RX   PubMed=1672363;
RX   PubMed=8609460;
RX   PubMed=16714754;
RX   PubMed=18079351;
CC   Doubling time: 46 hours (PubMed=8609460).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_2552 ! LB182
SX   Male
AG   51Y
CA   Finite cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 13
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RX   PubMed=1372096; DOI=10.1016/0921-8777(92)90074-d;
RA   Arlett C.F., Harcourt S.A., Cole J., Green M.H.L., Anstey A.V.;
RT   "A comparison of the response of unstimulated and stimulated
RT   T-lymphocytes and fibroblasts from normal, xeroderma pigmentosum and
RT   trichothiodystrophy donors to the lethal action of UV-C.";
RL   Mutat. Res. 273:127-135(1992).
//
RX   PubMed=1672363; DOI=10.1080/09553009114550661;
RA   Green M.H.L., Arlett C.F., Cole J., Harcourt S.A., Priestley A.,
RA   Waugh A.P.W., Stephens G., Beare D.M., Brown N.A.P., Shun-Shin G.A.;
RT   "Comparative human cellular radiosensitivity: III. Gamma-radiation
RT   survival of cultured skin fibroblasts and resting T-lymphocytes from
RT   the peripheral blood of the same individual.";
RL   Int. J. Radiat. Biol. 59:749-765(1991).
//
RX   PubMed=8609460; DOI=10.1080/095530096146075;
RA   Alsbeih G.A., Fertil B., Arlett C.F., Malaise E.-P.;
RT   "High split-dose recovery in hypersensitive human fibroblasts: a case
RT   of induced radioresistance?";
RL   Int. J. Radiat. Biol. 69:225-239(1996).
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RX   PubMed=16714754; DOI=10.1259/bjr/83726649;
RA   Arlett C.F., Plowman P.N., Rogers P.B., Parris C.N., Abbaszadeh F.,
RA   Green M.H.L., McMillan T.J., Bush C., Foray N., Lehmann A.R.;
RT   "Clinical and cellular ionizing radiation sensitivity in a patient
RT   with xeroderma pigmentosum.";
RL   Br. J. Radiol. 79:510-517(2006).
//
RX   PubMed=18079351; DOI=10.1259/bjr/27072321;
RA   Arlett C.F., Green M.H.L., Rogers P.B., Lehmann A.R., Plowman P.N.;
RT   "Minimal ionizing radiation sensitivity in a large cohort of xeroderma
RT   pigmentosum fibroblasts.";
RL   Br. J. Radiol. 81:51-58(2008).
//