ID   V79
AC   CVCL_2234
SY   V-79; V 79; Strain V; V79-1; GM00215; GM-215; GM00215A; GM16136; UCW 100
DR   BTO; BTO:0001425
DR   CLO; CLO_0009500
DR   CLO; CLO_0018898
DR   CLO; CLO_0025501
DR   CLO; CLO_0051573
DR   CLDB; cl4625
DR   CLDB; cl4626
DR   CLDB; cl4627
DR   CLDB; cl4628
DR   CLDB; cl4952
DR   CCRID; 3101HAMGNHa6
DR   CCRID; 5301HAM-KCB93015YJ
DR   ChEMBL-Cells; CHEMBL3307528
DR   ChEMBL-Targets; CHEMBL614074
DR   CLS; 305012
DR   Coriell; GM00215
DR   Coriell; GM16136
DR   DSMZ; ACC-335
DR   DSMZCellDive; ACC-335
DR   ECACC; 86041102
DR   ICLC; AL99002
DR   KCB; KCB 93015YJ
DR   Lonza; 731
DR   PubChem_Cell_line; CVCL_2234
DR   RCB; RCB0008
DR   Wikidata; Q54992521
RX   CelloPub=CLPUB00447;
RX   DOI=10.5962/bhl.title.4090;
RX   PubMed=688393;
RX   PubMed=3030579;
RX   PubMed=3558490;
RX   PubMed=8320183;
RX   PubMed=13576097;
RX   PubMed=13726391;
RX   PubMed=13901497;
CC   Characteristics: Widely used to study DNA damage induced by X-ray, UV radiation and oxidizing agents.
CC   Doubling time: ~16-20 hours (DSMZ=ACC-335).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from child cell line V79-4).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from child cell line V79-4).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 32
//
RX   CelloPub=CLPUB00447;
RA   Mulivor R.A., Suchy S.F.;
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992).
//
RX   DOI=10.5962/bhl.title.4090;
RA   Coriell L.L., Greene A.E.;
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 4th edition. October 1977.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda (1977).
//
RX   PubMed=688393; DOI=10.1016/0092-8674(78)90354-9;
RA   Gupta R.S., Chan D.Y.-H., Siminovitch L.;
RT   "Evidence for functional hemizygosity at the Emtr locus in CHO cells
RT   through segregation analysis.";
RL   Cell 14:1007-1013(1978).
//
RX   PubMed=3030579; DOI=10.1093/carcin/8.4.553;
RA   Palekar L.D., Eyre J.F., Most B.M., Coffin D.L.;
RT   "Metaphase and anaphase analysis of V79 cells exposed to erionite,
RT   UICC chrysotile and UICC crocidolite.";
RL   Carcinogenesis 8:553-560(1987).
//
RX   PubMed=3558490; DOI=10.1002/jcp.1041300303;
RA   Gupta R.S., Dudani A.K.;
RT   "Species-specific differences in the toxicity of rhodamine 123 towards
RT   cultured mammalian cells.";
RL   J. Cell. Physiol. 130:321-327(1987).
//
RX   PubMed=8320183; DOI=10.1007/BF02633962;
RA   Ichinose I., Nakano S., Esaki T., Koga T., Mitsugi K., Yamada H.,
RA   Niho Y.;
RT   "Growth modulation of human tumor cells by a growth-inhibiting
RT   activity derived from tumorigenic V79 Chinese hamster cells.";
RL   In Vitro Cell. Dev. Biol. Anim. 29:332-338(1993).
//
RX   PubMed=13576097; DOI=10.1093/jnci/21.2.393;
RA   Ford D.K., Yerganian G.;
RT   "Observations on the chromosomes of Chinese hamster cells in tissue
RT   culture.";
RL   J. Natl. Cancer Inst. 21:393-425(1958).
//
RX   PubMed=13726391; DOI=10.2307/3570945;
RA   Elkind M.M., Sutton H.;
RT   "Radiation response of mammalian cells grown in culture. 1. Repair of
RT   X-ray damage in surviving Chinese hamster cells.";
RL   Radiat. Res. 13:556-593(1960).
//
RX   PubMed=13901497; DOI=10.1080/09553006114551111;
RA   Greenblatt C.L.;
RT   "The evaluation of X-ray-induced chromosome aberrations in
RT   cell-cultures of the Chinese hamster.";
RL   Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 4:185-210(1961).
//