ID   UPCI-SCC-114
AC   CVCL_2227
SY   UPCI:SCC114; SCC114
DR   BioSample; SAMN03473476
DR   cancercelllines; CVCL_2227
DR   DSMZ; ACC-662
DR   DSMZCellDive; ACC-662
DR   IARC_TP53; 18362
DR   Wikidata; Q54991670
RX   PubMed=12872257;
RX   PubMed=17112776;
CC   Population: Caucasian.
CC   Doubling time: ~60 hours (DSMZ=ACC-662).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=12872257).
CC   Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
ST   Source(s): DSMZ=ACC-662
ST   Amelogenin: X
ST   CSF1PO: 13
ST   D13S317: 11,12
ST   D16S539: 11,12
ST   D18S51: 12,17
ST   D19S433: 14
ST   D21S11: 27,30
ST   D2S1338: 17
ST   D3S1358: 18
ST   D5S818: 11
ST   D7S820: 8,12
ST   D8S1179: 13
ST   FGA: 19,22
ST   Penta D: 9,12
ST   Penta E: 13
ST   TH01: 7,9.3
ST   TPOX: 9,11
ST   vWA: 16,20
DI   NCIt; C4041; Floor of mouth squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   71Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 22
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M.,
RA   Ishwad C.S., Jarvik J.W.;
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//