ID   UPCI-SCC-111
AC   CVCL_2226
SY   UPCI:SCC111; SCC111; SCC-111
DR   BioSample; SAMN03473480
DR   cancercelllines; CVCL_2226
DR   Cosmic; 927220
DR   Cosmic; 932154
DR   DepMap; ACH-001696
DR   DSMZ; ACC-666
DR   DSMZCellDive; ACC-666
DR   IARC_TP53; 18361
DR   Wikidata; Q54991668
RX   PubMed=12872257;
RX   PubMed=17112776;
RX   PubMed=17681875;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Caucasian.
CC   Doubling time: ~40 hours (DSMZ=ACC-666).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Unspecified (PubMed=12872257).
CC   Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
ST   Source(s): DSMZ=ACC-666
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,13
ST   D16S539: 9,12
ST   D18S51: 16.2
ST   D19S433: 14
ST   D21S11: 29,30,31
ST   D2S1338: 19,26
ST   D3S1358: 17
ST   D5S818: 12
ST   D7S820: 8,10
ST   D8S1179: 13,14
ST   FGA: 20
ST   Penta D: 11,14
ST   Penta E: 13
ST   TH01: 8,10
ST   TPOX: 8,11
ST   vWA: 18
DI   NCIt; C4041; Floor of mouth squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 23
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692;
RA   White, Jason S.
RA   Weissfeld, Joel L.
RA   Ragin, Camille C.R.
RA   Rossie, Karen M.
RA   Martin, Christa Lese
RA   Shuster, Michele
RA   Ishwad, Chandramohan S.
RA   Law, John C.
RA   Myers, Eugene Nicholas
RA   Johnson, Jonas T.
RA   Gollin, Susanne M.
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065;
RA   Martin, Christa Lese
RA   Reshmi, Shalini C.
RA   Ried, Thomas
RA   Gottberg, William
RA   Wilson, John W.
RA   Reddy, Jaya K.
RA   Khanna, Poornima
RA   Johnson, Jonas T.
RA   Myers, Eugene Nicholas
RA   Gollin, Susanne M.
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer, Cheryl A.
RA   An, Ji-Yan
RA   Malehorn, David E.
RA   Zeng, Xue-Mei
RA   Gollin, Susanne M.
RA   Ishwad, Chandramohan S.
RA   Jarvik, Jonathan W.
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//