ID TC-71 AC CVCL_2213 SY TC71; GM11654 DR BTO; BTO_0002604 DR CLO; CLO_0009879 DR CLO; CLO_0021329 DR EFO; EFO_0002865 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR BioGRID_ORCS_Cell_line; 200 DR BioSample; SAMN03473241 DR BioSample; SAMN10987608 DR cancercelllines; CVCL_2213 DR Cell_Model_Passport; SIDM00419 DR Coriell; GM11654 DR Cosmic; 1078383 DR Cosmic; 1082507 DR Cosmic; 1112132 DR Cosmic; 1718433 DR Cosmic; 2228246 DR Cosmic; 2250474 DR Cosmic; 2294589 DR Cosmic-CLP; 1240221 DR DepMap; ACH-000424 DR DSMZ; ACC-516 DR DSMZCellDive; ACC-516 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 1240221 DR GEO; GSM510013 DR GEO; GSM887689 DR GEO; GSM888781 DR GEO; GSM1670525 DR GEO; GSM1676323 DR GEO; GSM1701656 DR GEO; GSM4368464 DR GEO; GSM5359718 DR GEO; GSM5359719 DR GEO; GSM5359720 DR GEO; GSM5359721 DR GEO; GSM5359722 DR GEO; GSM5359723 DR GEO; GSM5362946 DR GEO; GSM5362947 DR GEO; GSM5362954 DR GEO; GSM5362956 DR GEO; GSM5362963 DR GEO; GSM5362964 DR GEO; GSM5364016 DR GEO; GSM5364017 DR GEO; GSM5364018 DR GEO; GSM5364019 DR GEO; GSM5364020 DR IARC_TP53; 15970 DR IARC_TP53; 27040 DR LiGeA; CCLE_900 DR LINCS_LDP; LCL-1438 DR PharmacoDB; TC71_1567_2019 DR PRIDE; PXD012680 DR PRIDE; PXD030304 DR Progenetix; CVCL_2213 DR Wikidata; Q54971816 RX DOI=10.5282/edoc.27750; RX PubMed=3004699; RX PubMed=3390826; RX PubMed=8040301; RX PubMed=8617485; RX PubMed=9823299; RX PubMed=11891184; RX PubMed=15150091; RX PubMed=18160777; RX PubMed=19787792; RX PubMed=20197622; RX PubMed=20922763; RX PubMed=21822310; RX PubMed=22142829; RX PubMed=22460905; RX PubMed=24312454; RX PubMed=25010205; RX PubMed=25223734; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25984343; RX PubMed=26351324; RX PubMed=26428435; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=29464090; RX PubMed=30879952; RX PubMed=30894373; RX PubMed=30962207; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; RX PubMed=36476851; WW Info; ESCLA; -; https://hgserver1.amc.nl/cgi-bin/r2/main.cgi?option=about_dscope WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Provider; CCR; -; https://www.cccells.org/PDF_Files/Ewings/TC-71.pdf WW Provider; CCR; -; https://www.cccells.org/tables/Ewings.php CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: Ewing Sarcoma Cell Line Atlas (ESCLA). CC Part of: MD Anderson Cell Lines Project. CC Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel. CC Population: Caucasian. CC Doubling time: 15 hours (PubMed=20922763); 21 hours (PubMed=24312454); 26 hours (PubMed=25984343); ~24 hours (DSMZ=ACC-516). CC HLA typing: A*02:01,68:01; B*15:07,44:02; C*03:03,05:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=18160777; PubMed=19787792; PubMed=25010205; PubMed=25223734). CC Sequence variation: Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (PubMed=8040301; PubMed=11891184; PubMed=25010205; PubMed=25485619; PubMed=36476851). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (PubMed=19787792; PubMed=25010205; PubMed=25223734; DepMap=ACH-000424). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Cys (c.733G>T); ClinVar=VCV000012349; Zygosity=Unspecified (PubMed=25010205). CC Omics: Genomics; ChIP-seq; FLI1. CC Omics: Genomics; ChIP-seq; H3K27ac. CC Omics: Genomics; ChIP-seq; H3K27me3. CC Omics: Genomics; ChIP-seq; H3K4me3. CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Genomics; Whole genome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Phenotyping; shRNA library screening. CC Omics: Proteomics. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Transcriptomics; RNAseq; Single cell. CC Omics: Variations; Array-based CGH. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.1%; Native American=0.12%; East Asian, North=1.75%; East Asian, South=0%; South Asian=0.97%; European, North=65.4%; European, South=31.66% (PubMed=30894373). CC Derived from site: In situ; Bone, humerus; UBERON=UBERON_0000976. ST Source(s): COG; Cosmic-CLP=1240221; DSMZ=ACC-516; PubMed=19787792; PubMed=20922763; PubMed=24312454; PubMed=25010205; PubMed=25877200; PubMed=30879952 ST Amelogenin: X (PubMed=25877200) ST Amelogenin: X,Y (COG; Cosmic-CLP=1240221; DSMZ=ACC-516; PubMed=19787792; PubMed=20922763; PubMed=24312454; PubMed=25010205; PubMed=30879952) ST CSF1PO: 10 (PubMed=25010205) ST CSF1PO: 10,11 (COG; Cosmic-CLP=1240221; DSMZ=ACC-516; PubMed=20922763; PubMed=24312454; PubMed=30879952) ST D13S317: 11,12 ST D16S539: 11,14 ST D18S51: 12,15 ST D19S433: 14 (DSMZ=ACC-516; PubMed=19787792; PubMed=25010205) ST D19S433: 14,16.2 (PubMed=24312454) ST D21S11: 29,30 ST D2S1338: 20,24 ST D3S1358: 15,17 ST D5S818: 10 ST D7S820: 10 ST D8S1179: 10 (DSMZ=ACC-516; PubMed=19787792) ST D8S1179: 10,12 (PubMed=20922763; PubMed=24312454; PubMed=25010205; PubMed=25877200) ST FGA: 24,26 ST Penta D: 11,14 ST Penta E: 12 ST SE33: 21,30.2 ST TH01: 9.3 ST TPOX: 8,9 ST vWA: 17 (COG; DSMZ=ACC-516; PubMed=20922763; PubMed=24312454; PubMed=25010205; PubMed=25877200) ST vWA: 17,18 (PubMed=19787792; PubMed=30879952) ST vWA: 17,19 (Cosmic-CLP=1240221) DI NCIt; C4817; Ewing sarcoma DI ORDO; Orphanet_319; Ewing sarcoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 22Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 46 CH CVCL_D6TX ! TC-71 EHD1 KO CH CVCL_QW72 ! TC-CD99-shRNA#1 CH CVCL_QW73 ! TC-CD99-shRNA#2 CH CVCL_QW71 ! TC-CTR-shRNA // RX PubMed=26428435; DOI=10.1016/j.ejca.2015.08.020; RA Sand, Laurens G.L. RA Scotlandi, Katia RA Berghuis, Dagmar RA Snaar-Jagalska, B. Ewa RA Picci, Piero RA Schmidt, Thomas RA Szuhai, Karoly RA Hogendoorn, Pancras Cornelis Wilhelmus RT "CXCL14, CXCR7 expression and CXCR4 splice variant ratio associate RT with survival and metastases in Ewing sarcoma patients."; RL Eur. J. Cancer 51:2624-2633(2015). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=24312454; DOI=10.1371/journal.pone.0080060; PMCID=PMC3846563; RA May, William A. RA Grigoryan, Rita S. RA Keshelava, Nino RA Cabral, Daniel J. RA Christensen, Laura L. RA Jenabi, Jasmine RA Ji, Ling-Yun RA Triche, Timothy J. RA Lawlor, Elizabeth R. RA Reynolds, Charles Patrick RT "Characterization and drug resistance patterns of Ewing's sarcoma RT family tumor cell lines."; RL PLoS ONE 8:e80060.1-e80060.10(2013). // RX PubMed=25223734; DOI=10.1158/2159-8290.CD-14-0622; PMCID=PMC4264969; RA Tirode, Franck RA Surdez, Didier RA Ma, Xiao-Tu RA Parker, Matthew RA Le Deley, Marie-Cecile RA Bahrami, Armita RA Zhang, Zhao-Jie RA Lapouble, Eve RA Grossetete-Lalami, Sandrine RA Rusch, Michael RA Reynaud, Stephanie RA Rio-Frio, Thomas RA Hedlund, Erin RA Wu, Gang RA Chen, Xiang RA Pierron, Gaelle RA Oberlin, Odile RA Zaidi, Sakina RA Lemmon, Gordon RA Gupta, Pankaj RA Vadodaria, Bhavin RA Easton, John RA Gut, Marta RA Ding, Li RA Mardis, Elaine R. RA Wilson, Richard K. RA Shurtleff, Sheila RA Laurence, Valerie RA Michon, Jean RA Marec-Berard, Perrine RA Gut, Ivo G. RA Downing, James R. RA Dyer, Michael Anthony RA Zhang, Jing-Hui RA Delattre, Olivier RG International Cancer Genome Consortium; RG St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project; RT "Genomic landscape of Ewing sarcoma defines an aggressive subtype with RT co-association of STAG2 and TP53 mutations."; RL Cancer Discov. 4:1342-1353(2014). // RX PubMed=18160777; DOI=10.1159/000109614; RA Savola, Suvi RA Nardi, Filippo RA Scotlandi, Katia RA Picci, Piero RA Knuutila, Sakari RT "Microdeletions in 9p21.3 induce false negative results in CDKN2A FISH RT analysis of Ewing sarcoma."; RL Cytogenet. Genome Res. 119:21-26(2007). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=29464090; DOI=10.18632/oncotarget.23815; PMCID=PMC5814230; RA Spurny, Christian RA Kailayangiri, Sareetha RA Altvater, Bianca RA Jamitzky, Silke RA Hartmann, Wolfgang RA Wardelmann, Eva RA Ranft, Andreas RA Dirksen, Uta RA Amler, Susanne RA Hardes, Jendrik RA Fluegge, Maike RA Meltzer, Jutta RA Farwick, Nicole RA Greune, Lea RA Rossig, Claudia RT "T cell infiltration into Ewing sarcomas is associated with local RT expression of immune-inhibitory HLA-G."; RL Oncotarget 9:6536-6549(2018). // RX PubMed=20922763; DOI=10.1002/pbc.22801; PMCID=PMC3005554; RA Kang, Min H. RA Smith, Malcolm A. RA Morton, Christopher L. RA Keshelava, Nino RA Houghton, Peter J. RA Reynolds, Charles Patrick RT "National Cancer Institute pediatric preclinical testing program: RT model description for in vitro cytotoxicity testing."; RL Pediatr. Blood Cancer 56:239-249(2011). // RX PubMed=21822310; DOI=10.1038/onc.2011.317; RA Mackintosh, Carlos RA Ordonez, Jose L. RA Garcia-Dominguez, Daniel J. RA Sevillano, Vicky RA Llombart-Bosch, Antonio RA Szuhai, Karoly RA Scotlandi, Katia RA Alberghini, Marco RA Sciot, Raf RA Sinnaeve, Friedl RA Hogendoorn, Pancras Cornelis Wilhelmus RA Picci, Piero RA Knuutila, Sakari RA Dirksen, Uta RA Debiec-Rychter, Maria RA Schaefer, Karl-Ludwig RA de Alava, Enrique RT "1q gain and CDT2 overexpression underlie an aggressive and highly RT proliferative form of Ewing sarcoma."; RL Oncogene 31:1287-1298(2012). // RX PubMed=11891184; DOI=10.1016/S0002-9440(10)64908-5; PMCID=PMC1867180; RA Manara, Maria Cristina RA Perbal, Bernard RA Benini, Stefania RA Strammiello, Rosaria RA Cerisano, Vanessa RA Perdichizzi, Stefania RA Serra, Massimo RA Astolfi, Annalisa RA Bertoni, Francesco RA Alami, Jennifer RA Yeger, Herman RA Picci, Piero RA Scotlandi, Katia RT "The expression of ccn3(nov) gene in musculoskeletal tumors."; RL Am. J. Pathol. 160:849-859(2002). // RX PubMed=30962207; DOI=10.15252/embr.201845766; PMCID=PMC6500973; RA Linden, Malin RA Thomsen, Christer RA Grundevik, Pernilla RA Jonasson, Emma RA Andersson, Daniel RA Runnberg, Rikard RA Dolatabadi, Soheila RA Vannas, Christoffer RA Santamaria, Manuel Luna RA Fagman, Henrik RA Stahlberg, Anders RA Aman, Pierre RT "FET family fusion oncoproteins target the SWI/SNF chromatin RT remodeling complex."; RL EMBO Rep. 20:e45766.1-e45766.15(2019). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=3390826; RA McKeon, Catherine RA Thiele, Carol Jeanne RA Ross, Robert A. RA Kwan, Michael RA Triche, Timothy J. RA Miser, James S. RA Israel, Mark A. RT "Indistinguishable patterns of protooncogene expression in two RT distinct but closely related tumors: Ewing's sarcoma and RT neuroepithelioma."; RL Cancer Res. 48:4307-4311(1988). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=8040301; DOI=10.1172/JCI117360; PMCID=PMC295111; RA Giovannini, Marco RA Biegel, Jaclyn A. RA Serra, Massimo RA Wang, Jian-Ying RA Wei, Ya-Lin H. RA Nycum, Lynn M. RA Emanuel, Beverly S. RA Evans, Glen A. RT "EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and RT primitive neuroectodermal tumors with variant translocations."; RL J. Clin. Invest. 94:489-496(1994). // RX PubMed=30879952; DOI=10.1016/j.ymthe.2019.02.014; PMCID=PMC6520468; RA Kailayangiri, Sareetha RA Altvater, Bianca RA Lesch, Stefanie RA Balbach, Sebastian T. RA Gottlich, Claudia RA Kuhnemundt, Johanna RA Mikesch, Jan-Henrik RA Schelhaas, Sonja RA Jamitzky, Silke RA Meltzer, Jutta RA Farwick, Nicole RA Greune, Lea RA Fluegge, Maike RA Kerl, Kornelius RA Lode, Holger N. RA Siebert, Nikolai RA Muller, Ingo RA Walles, Heike RA Hartmann, Wolfgang RA Rossig, Claudia RT "EZH2 inhibition in Ewing sarcoma upregulates GD2 expression for RT targeting with gene-modified T cells."; RL Mol. Ther. 27:933-946(2019). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin K. RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=3004699; DOI=10.1016/0165-4608(86)90001-4; RA Whang-Peng, Jacqueline RA Triche, Timothy J. RA Knutsen, Turid RA Miser, James S. RA Kao-Shan, Chien-Song RA Tsai, Schickwann RA Israel, Mark A. RT "Cytogenetic characterization of selected small round cell tumors of RT childhood."; RL Cancer Genet. Cytogenet. 21:185-208(1986). // RX PubMed=15150091; DOI=10.1158/0008-5472.CAN-03-0809; RA Schaefer, Karl-Ludwig RA Brachwitz, Kristin RA Wai, Daniel H. RA Braun, Yvonne RA Diallo, Raihanatou RA Korsching, Eberhard RA Eisenacher, Martin RA Voss, Reinhard RA van Valen, Frans RA Baer, Claudia RA Selle, Barbara RA Spahn, Laura RA Liao, Shuen-Kuei RA Lee, Kevin A.W. RA Hogendoorn, Pancras Cornelis Wilhelmus RA Reifenberger, Guido RA Gabbert, Helmut Erich RA Poremba, Christopher RT "Expression profiling of t(12;22) positive clear cell sarcoma of soft RT tissue cell lines reveals characteristic up-regulation of potential RT new marker genes including ERBB3."; RL Cancer Res. 64:3395-3405(2004). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura E. RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX DOI=10.5282/edoc.27750; RA Orth, Martin Franz RT "Systematic multi-omics profiling of Ewing sarcoma cell lines."; RL Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany. // RX PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652; RA Cowley, Glenn S. RA Weir, Barbara A. RA Vazquez, Francisca RA Tamayo, Pablo RA Scott, Justine A. RA Rusin, Scott RA East-Seletsky, Alexandra RA Ali, Levi D. RA Gerath, William F.J. RA Pantel, Sarah E. RA Lizotte, Patrick Hall RA Jiang, Guo-Zhi RA Hsiao, Jessica RA Tsherniak, Aviad RA Dwinell, Elizabeth RA Aoyama, Simon RA Okamoto, Michael RA Harrington, William RA Gelfand, Ellen T. RA Green, Thomas M. RA Tomko, Mark J. RA Gopal, Shuba RA Wong, Terence C. RA Li, Hu-Bo RA Howell, Sara RA Stransky, Nicolas RA Liefeld, Ted RA Jang, Dongkeun RA Bistline, Jonathan RA Meyers, Barbara Hill RA Armstrong, Scott Allen RA Anderson, Kenneth Carl RA Stegmaier, Kimberly RA Reich, Michael RA Pellman, David RA Boehm, Jesse S. RA Mesirov, Jill P. RA Golub, Todd Robert RA Root, David E. RA Hahn, William Chun RT "Parallel genome-scale loss of function screens in 216 cancer cell RT lines for the identification of context-specific genetic RT dependencies."; RL Sci. Data 1:140035.1-140035.12(2014). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, A. Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=9823299; RA Khan, Javed RA Simon, Richard M. RA Bittner, Michael RA Chen, Yi-Dong RA Leighton, Stephen B. RA Pohida, Thomas RA Smith, Paul D. RA Jiang, Yuan RA Gooden, Gerald C. RA Trent, Jeffrey M. RA Meltzer, Paul S. RT "Gene expression profiling of alveolar rhabdomyosarcoma with cDNA RT microarrays."; RL Cancer Res. 58:5009-5013(1998). // RX PubMed=19787792; DOI=10.1002/gcc.20717; RA Ottaviano, Laura RA Schaefer, Karl-Ludwig RA Gajewski, Melanie RA Huckenbeck, Wolfgang RA Baldus, Stefan E. RA Rogel, Uwe RA Mackintosh, Carlos RA de Alava, Enrique RA Myklebost, Ola RA Kresse, Stine Henrichson RA Meza-Zepeda, Leonardo Andres RA Serra, Massimo RA Cleton-Jansen, Anne-Marie RA Hogendoorn, Pancras Cornelis Wilhelmus RA Buerger, Horst RA Aigner, Thomas RA Gabbert, Helmut Erich RA Poremba, Christopher RT "Molecular characterization of commonly used cell lines for bone tumor RT research: a trans-European EuroBoNet effort."; RL Genes Chromosomes Cancer 49:40-51(2010). // RX PubMed=8617485; DOI=10.1016/S0046-8177(96)90115-X; RA Scotlandi, Katia RA Serra, Massimo RA Manara, Maria Cristina RA Benini, Stefania RA Sarti, Manuela RA Maurici, Daniela RA Lollini, Pier-Luigi RA Picci, Piero RA Bertoni, Francesco RA Baldini, Nicola RT "Immunostaining of the p30/32MIC2 antigen and molecular detection of RT EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral RT neuroectodermal tumor."; RL Hum. Pathol. 27:408-416(1996). // RX PubMed=22142829; DOI=10.1158/1078-0432.CCR-11-2056; PMCID=PMC3271129; RA Shukla, Neerav RA Ameur, Nabahet RA Yilmaz, Ismail RA Nafa, Khedoudja RA Lau, Chyau-Yueh RA Marchetti, Angela RA Borsu, Laetitia RA Barr, Frederic G. RA Ladanyi, Marc RT "Oncogene mutation profiling of pediatric solid tumors reveals RT significant subsets of embryonal rhabdomyosarcoma and neuroblastoma RT with mutated genes in growth signaling pathways."; RL Clin. Cancer Res. 18:748-757(2012). // RX PubMed=20197622; DOI=10.1172/JCI36667; PMCID=PMC2827943; RA Rocchi, Anna RA Manara, Maria Cristina RA Sciandra, Marika RA Zambelli, Diana RA Nardi, Filippo RA Nicoletti, Giordano RA Garofalo, Cecilia RA Meschini, Stefania RA Astolfi, Annalisa RA Colombo, Mario P. RA Lessnick, Stephen Lee RA Picci, Piero RA Scotlandi, Katia RT "CD99 inhibits neural differentiation of human Ewing sarcoma cells and RT thereby contributes to oncogenesis."; RL J. Clin. 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RA Laudeman, Julie RA Ogle, Chad RA Reinhart, Russell RA Selby, Michael RA Connelly, John RA Harris, Erik RA Monks, Anne RA Morris, Joel RT "Sarcoma cell line screen of oncology drugs and investigational agents RT identifies patterns associated with gene and microRNA expression."; RL Mol. Cancer Ther. 14:2452-2462(2015). // RX PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782; RA Brohl, Andrew S. RA Solomon, David A. RA Chang, Wendy RA Wang, Jian-Jun RA Song, Young RA Sindiri, Sivasish RA Patidar, Rajesh RA Hurd, Laura RA Chen, Li RA Shern, Jack F. RA Liao, Hong-Ling RA Wen, Xin-Yu RA Gerard, Julia RA Kim, Jung-Sik RA Lopez Guerrero, Jose Antonio RA Machado, Isidro RA Wai, Daniel H. RA Picci, Piero RA Triche, Timothy J. RA Horvai, Andrew E. RA Miettinen, Markku Martti RA Wei, Jun S. RA Catchpoole, Daniel RA Llombart-Bosch, Antonio RA Waldman, Todd A. RA Khan, Javed RT "The genomic landscape of the Ewing sarcoma family of tumors reveals RT recurrent STAG2 mutation."; RL PLoS Genet. 10:e1004475.1-e1004475.13(2014). //