ID   SH-2 [Human leukemia]
AC   CVCL_2190
DR   BioSample; SAMN03473457
DR   cancercelllines; CVCL_2190
DR   DSMZ; ACC-643
DR   DSMZCellDive; ACC-643
DR   GEO; GSM1446761
DR   Wikidata; Q54953197
RX   PubMed=18715689;
RX   PubMed=19954598;
CC   Population: Chinese.
CC   Doubling time: ~80 hours (DSMZ=ACC-643).
CC   Karyotypic information: Has lost chromosome Y (PubMed=18715689; PubMed=19954598).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln192His (c.576G>T); ClinVar=VCV000922531; Zygosity=Hemizygous (PubMed=18715689; PubMed=19954598).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): DSMZ=ACC-643; PubMed=18715689
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 10,12
ST   D16S539: 9
ST   D18S51: 13,22
ST   D19S433: 14,15
ST   D21S11: 30
ST   D2S1338: 18,20
ST   D3S1358: 15,17
ST   D5S818: 10,11
ST   D7S820: 12
ST   D8S1179: 14,15
ST   FGA: 23,25
ST   Penta D: 9
ST   Penta E: 15,19
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 18,20
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 23
//
RX   PubMed=18715689; DOI=10.1016/j.exphem.2008.06.013;
RA   Qiu, Hui-Ying
RA   Xue, Yong-Quan
RA   Zhang, Jun
RA   Pan, Jin-Lan
RA   Dai, Hai-Ping
RA   Wu, Ya-Fang
RA   Wang, Yong
RA   Chen, Su-Ning
RA   Wu, De-Pei
RT   "Establishment and characterization of a new human acute myelocytic
RT   leukemia cell line SH-2 with a loss of Y chromosome, a derivative
RT   chromosome 16 resulting from an unbalanced translocation between
RT   chromosomes 16 and 17, monosomy 17, trisomy 19, and p53 alteration.";
RL   Exp. Hematol. 36:1487-1495(2008).
//
RX   PubMed=19954598; DOI=10.3760/cma.j.issn.0253-2727.2009.07.009;
RA   Qiu, Hui-Ying
RA   Xue, Yong-Quan
RA   Zhang, Jun
RA   Dai, Hai-Ping
RA   Pan, Jin-Lan
RA   Wu, Ya-Fang
RA   Chen, Su-Ning
RA   Wang, Yong
RA   Shen, Juan
RA   Sun, Ai-Ning
RA   Wu, De-Pei
RT   "Establishment and characterization of a new human myeloid leukemia
RT   cell line SH-2.";
RL   Zhonghua Xue Ye Xue Za Zhi 30:458-463(2009).
//