ID   ES-R1
AC   CVCL_2167
SY   R1; R1 ES; R-1
DR   BTO; BTO_0004500
DR   CLO; CLO_0008697
DR   EFO; EFO_0002076
DR   ATCC; SCRC-1011
DR   CCRID; 3101MOUSCSP223
DR   ChEMBL-Cells; CHEMBL3307379
DR   ChEMBL-Targets; CHEMBL614383
DR   ECACC; 07072001
DR   ENCODE; ENCBS054ZRK
DR   ENCODE; ENCBS388DNV
DR   ENCODE; ENCBS398YOV
DR   MMRRC; MMRRC:011978-UCD
DR   PRIDE; PRD000194
DR   PRIDE; PXD000589
DR   PubChem_Cell_line; CVCL_2167
DR   Wikidata; Q54832454
RX   PubMed=8378314;
RX   PubMed=9353641;
RX   PubMed=20512790;
RX   PubMed=25277546;
RX   PubMed=25894527;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/r/cell-lines-detail-521.html
WW   Provider; Michigan TCPS; -; https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/transgenic-animal-model/transgenic-core-products-services
CC   Omics: Proteomics.
CC   Omics: Proteomics; Subcellular; Cell surface.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
CC   Breed/subspecies: 129X1/SvJ x 129S1/Sv-Oca2+Tyr+KitlSl-J.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 28
CH   CVCL_B3PW ! Dnmt1(Y495C)-1
CH   CVCL_BW90 ! ES-R1 CAG-S-hCOUP-TFI
CH   CVCL_BW91 ! ES-R1 CAG-S-hERalpha
CH   CVCL_BW92 ! ES-R1 CAG-S-hERRalpha
CH   CVCL_BW93 ! ES-R1 CAG-S-hPPARgamma2
CH   CVCL_BW94 ! ES-R1 CAG-S-hRXRalpha
CH   CVCL_BW95 ! ES-R1 CAG-S-hSRC-1
CH   CVCL_BW96 ! ES-R1 CAG-S-hSRC-2
CH   CVCL_BW97 ! ES-R1 CAG-S-mPPARalpha
CH   CVCL_6767 ! ES-R1/7AC5/EYFP
CH   CVCL_AR60 ! ES-R1/B5/EGFP
CH   CVCL_AR61 ! ES-R1/CK6/ECFP
CH   CVCL_AR62 ! ES-R1/CK8/ECFP
CH   CVCL_AR63 ! ES-R1/D4/XEGFP
CH   CVCL_6516 ! ES-R1/E
CH   CVCL_AR64 ! ES-R1/YC5/EYFP
CH   CVCL_D0QI ! R1-Dnmt1WT-1
CH   CVCL_WS52 ! R1-Oct4-EGFP
//
RX   PubMed=9353641; DOI=10.1538/expanim.46.311;
RA   Kyuwa, Shigeru
RT   "Replication of murine coronaviruses in mouse embryonic stem cell
RT   lines in vitro.";
RL   Exp. Anim. 46:311-313(1997).
//
RX   PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347;
RA   Bausch-Fluck, Damaris
RA   Hofmann, Andreas
RA   Bock, Thomas
RA   Frei, Andreas P.
RA   Cerciello, Ferdinando
RA   Jacobs, Andrea
RA   Moest, Hansjoerg
RA   Omasits, Ulrich
RA   Gundry, Rebekah L.
RA   Yoon, Charles
RA   Schiess, Ralph
RA   Schmidt, Alexander
RA   Mirkowska, Paulina
RA   Hartlova, Anetta Svitorka
RA   Van Eyk, Jennifer Eileen
RA   Bourquin, Jean-Pierre
RA   Aebersold, Ruedi
RA   Boheler, Kenneth R.
RA   Zandstra, Peter W.
RA   Wollscheid, Bernd
RT   "A mass spectrometric-derived cell surface protein atlas.";
RL   PLoS ONE 10:e0121314.1-e0121314.22(2015).
//
RX   PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738;
RA   Didion, John Paul
RA   Buus, Ryan John
RA   Naghashfar, Zohreh
RA   Threadgill, David W.
RA   Morse, Herbert Carpenter 3rd
RA   Pardo-Manuel de Villena, Fernando
RT   "SNP array profiling of mouse cell lines identifies their strains of
RT   origin and reveals cross-contamination and widespread aneuploidy.";
RL   BMC Genomics 15:847.1-847.11(2014).
//
RX   PubMed=20512790; DOI=10.1002/pmic.201000039; PMCID=PMC2934747;
RA   Gundry, Rebekah L.
RA   Tchernyshyov, Irina
RA   Sheng, Shi-Jun
RA   Tarasova, Yelena S.
RA   Raginski, Kimberly
RA   Boheler, Kenneth R.
RA   Van Eyk, Jennifer Eileen
RT   "Expanding the mouse embryonic stem cell proteome: combining three
RT   proteomic approaches.";
RL   Proteomics 10:2728-2732(2010).
//
RX   PubMed=8378314; DOI=10.1073/pnas.90.18.8424; PMCID=PMC47369;
RA   Nagy, Andras
RA   Rossant, Janet
RA   Nagy, Rika
RA   Abramow-Newerly, Wanda
RA   Roder, John Carlin
RT   "Derivation of completely cell culture-derived mice from early-passage
RT   embryonic stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:8424-8428(1993).
//