ID   M-07e
AC   CVCL_2106
SY   M-07E; M-O7e; M07-e; M07e; Mo7e; MO7e; M07E; MO7E
DR   BTO; BTO_0005248
DR   CLO; CLO_0007447
DR   EFO; EFO_0022426
DR   CLDB; cl3281
DR   CLDB; cl7156
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-7721
DR   ArrayExpress; E-MTAB-7722
DR   BioSample; SAMN03473408
DR   BioSample; SAMN10988568
DR   cancercelllines; CVCL_2106
DR   CCRID; 1101HUM-PUMC000112
DR   Cell_Model_Passport; SIDM01640
DR   CLS; 305105
DR   Cosmic; 787447
DR   Cosmic; 975265
DR   Cosmic; 999723
DR   Cosmic; 1012082
DR   Cosmic; 1181607
DR   Cosmic; 1281323
DR   Cosmic; 1524835
DR   Cosmic; 1633511
DR   Cosmic; 2306215
DR   DepMap; ACH-000602
DR   DSMZ; ACC-104
DR   DSMZCellDive; ACC-104
DR   GEO; GSM236792
DR   GEO; GSM236828
DR   GEO; GSM743416
DR   GEO; GSM887287
DR   GEO; GSM888362
DR   GEO; GSM1446743
DR   IARC_TP53; 30115
DR   ICLC; HTL04002
DR   LiGeA; CCLE_603
DR   Lonza; 485
DR   NCBI_Iran; C621
DR   PharmacoDB; M07e_875_2019
DR   Progenetix; CVCL_2106
DR   Wikidata; Q54903379
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=2273055;
RX   PubMed=9096695;
RX   PubMed=11414198;
RX   PubMed=16408098;
RX   PubMed=22460905;
RX   PubMed=28109323;
RX   PubMed=30285677;
RX   PubMed=30629668;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31160637;
RX   PubMed=36982453;
WW   Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=MO7E
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: LL-100 blood cancer cell line panel.
CC   Population: Caucasian.
CC   Doubling time: 46 +- 12 hours (PubMed=9096695); ~40 hours (DSMZ=ACC-104).
CC   HLA typing: A*24:02:01,66:01:01; B*13:02:01,49:01:01; C*06:02:01;07:01:01 (DSMZCellDive=ACC-104).
CC   Sequence variation: Gene fusion; HGNC; HGNC:31677; ANO7 + HGNC; HGNC:17887; DHDH; Name(s)=ANO7-DHDH (PubMed=31160637).
CC   Sequence variation: Gene fusion; HGNC; HGNC:1537; CBFA2T3 + HGNC; HGNC:29450; GLIS2; Name(s)=CBFA2T3-GLIS2, ETO2-GLIS2 (PubMed=28109323).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (DepMap=ACH-000602).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=8.96%; Native American=0%; East Asian, North=0.92%; East Asian, South=0%; South Asian=3.01%; European, North=45.47%; European, South=41.63% (PubMed=30894373).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): CCRID=1101HUM-PUMC000112; DSMZ=ACC-104
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 10,11
ST   D16S539: 11
ST   D18S51: 15,20
ST   D19S433: 14,15
ST   D21S11: 30,32.2
ST   D2S1338: 19,25
ST   D3S1358: 16,19
ST   D5S818: 11
ST   D7S820: 11
ST   D8S1179: 13 (DSMZ=ACC-104)
ST   D8S1179: 13,16 (CCRID=1101HUM-PUMC000112)
ST   FGA: 18,22
ST   Penta D: 9
ST   Penta E: 12,14
ST   TH01: 6,8
ST   TPOX: 8
ST   vWA: 16,18
DI   NCIt; C7972; Childhood acute megakaryoblastic leukemia
DI   ORDO; Orphanet_518; Acute megakaryoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D630 ! M-07
SX   Female
AG   6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 41
CH   CVCL_RM07 ! M-07e/TPO
//
RX   PubMed=30629668; DOI=10.1371/journal.pone.0210404; PMCID=PMC6328144;
RA   Uphoff, Cord C.
RA   Pommerenke, Claudia
RA   Denkmann, Sabine A.
RA   Drexler, Hans Gunther
RT   "Screening human cell lines for viral infections applying RNA-Seq data
RT   analysis.";
RL   PLoS ONE 14:e0210404.1-e0210404.22(2019).
//
RX   PubMed=16408098; DOI=10.1038/sj.leu.2404081;
RA   Quentmeier, Hilmar
RA   MacLeod, Roderick A.F.
RA   Zaborski, Margarete
RA   Drexler, Hans Gunther
RT   "JAK2 V617F tyrosine kinase mutation in cell lines derived from
RT   myeloproliferative disorders.";
RL   Leukemia 20:471-476(2006).
//
RX   PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786;
RA   Tan, Kar-Tong
RA   Ding, Ling-Wen
RA   Sun, Qiao-Yang
RA   Lao, Zhen-Tang
RA   Chien, Wenwen
RA   Ren, Xi
RA   Xiao, Jin-Fen
RA   Loh, Xin-Yi
RA   Xu, Liang
RA   Lill, Michael
RA   Mayakonda, Anand
RA   Lin, De-Chen
RA   Yang, Henry He
RA   Koeffler, Harold Phillip
RT   "Profiling the B/T cell receptor repertoire of lymphocyte derived cell
RT   lines.";
RL   BMC Cancer 18:940.1-940.13(2018).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
RA   Berger, Michael F.
RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
RA   Korejwa, Adam
RA   Jane-Valbuena, Judit
RA   Mapa, Felipa A.
RA   Thibault, Joseph
RA   Bric-Furlong, Eva
RA   Raman, Pichai
RA   Shipway, Aaron
RA   Engels, Ingo H.
RA   Cheng, Jill
RA   Yu, Guo-Ying K.
RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
RA   Jagtap, Kalpana
RA   Jones, Michael D.
RA   Wang, Li
RA   Hatton, Charles
RA   Palescandolo, Emanuele
RA   Gupta, Supriya
RA   Mahan, Scott
RA   Sougnez, Carrie
RA   Onofrio, Robert C.
RA   Liefeld, Ted
RA   MacConaill, Laura E.
RA   Winckler, Wendy
RA   Reich, Michael
RA   Li, Nan-Xin
RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
RA   Golub, Todd Robert
RA   Morrissey, Michael P.
RA   Sellers, William Raj
RA   Schlegel, Robert
RA   Garraway, Levi Alexander
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=36982453; DOI=10.3390/ijms24065377; PMCID=PMC10049680;
RA   Skopek, Rafal
RA   Palusinska, Malgorzata
RA   Kaczor-Keller, Katarzyna
RA   Pingwara, Rafal
RA   Papierniak-Wygladala, Anna
RA   Schenk, Tino
RA   Lewicki, Slawomir
RA   Zelent, Artur
RA   Szymanski, Lukasz
RT   "Choosing the right cell line for acute myeloid leukemia (AML)
RT   research.";
RL   Int. J. Mol. Sci. 24:5377.1-5377.34(2023).
//
RX   PubMed=9096695; DOI=10.1038/sj.leu.2400621;
RA   Drexler, Hans Gunther
RA   Zaborski, Margarete
RA   Quentmeier, Hilmar
RT   "Thrombopoietin supports the continuous growth of cytokine-dependent
RT   human leukemia cell lines.";
RL   Leukemia 11:541-551(1997).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=28109323; DOI=10.1186/s13045-017-0396-0; PMCID=PMC5251306;
RA   Masetti, Riccardo
RA   Bertuccio, Salvatore Nicola
RA   Astolfi, Annalisa
RA   Chiarini, Francesca
RA   Lonetti, Annalisa
RA   Indio, Valentina
RA   De Luca, Matilde
RA   Bandini, Jessica
RA   Serravalle, Salvatore
RA   Franzoni, Monica
RA   Pigazzi, Martina
RA   Martelli, Alberto Maria
RA   Basso, Giuseppe
RA   Locatelli, Franco
RA   Pession, Andrea
RT   "Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion
RT   gene.";
RL   J. Hematol. Oncol. 10:26.1-26.5(2017).
//
RX   PubMed=2273055; DOI=10.1002/jcp.1041450310;
RA   Avanzi, Gian Carlo
RA   Brizzi, Maria Felice
RA   Witek-Giannotti, JoAnn S.
RA   Brennan, Agnes
RA   Yang, Yu-Chung
RA   Pegoraro, Luigi
RA   Clark, Steven C.
RT   "M-07e human leukemic factor-dependent cell line provides a rapid and
RT   sensitive bioassay for the human cytokines GM-CSF and IL-3.";
RL   J. Cell. Physiol. 145:458-464(1990).
//
RX   PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646;
RA   Quentmeier, Hilmar
RA   Pommerenke, Claudia
RA   Dirks, Wilhelm Gerhard
RA   Eberth, Sonja
RA   Koeppel, Max
RA   MacLeod, Roderick A.F.
RA   Nagel, Stefan
RA   Steube, Klaus G.
RA   Uphoff, Cord C.
RA   Drexler, Hans Gunther
RT   "The LL-100 panel: 100 cell lines for blood cancer studies.";
RL   Sci. Rep. 9:8218.1-8218.14(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=11414198; DOI=10.1007/s004320000207;
RA   Lahm, Harald
RA   Andre, Sabine
RA   Hoeflich, Andreas
RA   Fischer, Jurgen R.
RA   Sordat, Bernard
RA   Kaltner, Herbert
RA   Wolf, Eckhard
RA   Gabius, Hans-Joachim
RT   "Comprehensive galectin fingerprinting in a panel of 61 human tumor
RT   cell lines by RT-PCR and its implications for diagnostic and
RT   therapeutic procedures.";
RL   J. Cancer Res. Clin. Oncol. 127:375-386(2001).
//