ID HCC202 AC CVCL_2062 SY HCC-202; HCC0202; Hamon Cancer Center 202 DR CLO; CLO_0003649 DR EFO; EFO_0001176 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ArrayExpress; E-TABM-157 DR ATCC; CRL-2316 DR BioGRID_ORCS_Cell_line; 660 DR BioSample; SAMN03471302 DR BioSample; SAMN10988183 DR cancercelllines; CVCL_2062 DR Cell_Model_Passport; SIDM00870 DR Cosmic; 687482 DR Cosmic; 904358 DR Cosmic; 1018461 DR Cosmic; 1047702 DR Cosmic; 1136360 DR Cosmic; 1287882 DR Cosmic; 1603209 DR Cosmic; 1935002 DR Cosmic; 1995429 DR Cosmic; 2165008 DR Cosmic-CLP; 1290906 DR DepMap; ACH-000725 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 1290906 DR GEO; GSM186725 DR GEO; GSM186726 DR GEO; GSM344369 DR GEO; GSM344419 DR GEO; GSM350515 DR GEO; GSM783972 DR GEO; GSM827455 DR GEO; GSM844089 DR GEO; GSM847342 DR GEO; GSM847484 DR GEO; GSM887047 DR GEO; GSM888117 DR GEO; GSM1053699 DR GEO; GSM1172872 DR GEO; GSM1172963 DR GEO; GSM1374510 DR GEO; GSM1669853 DR IARC_TP53; 28273 DR KCLB; 9S0202 DR LiGeA; CCLE_133 DR LINCS_HMS; 50214 DR LINCS_LDP; LCL-1333 DR PharmacoDB; HCC202_487_2019 DR PRIDE; PXD000309 DR Progenetix; CVCL_2062 DR SLKBase; 3500 DR Wikidata; Q54881628 RX PubMed=9833771; RX PubMed=11314036; RX PubMed=17157791; RX PubMed=19582160; RX PubMed=20215515; RX PubMed=22414580; RX PubMed=22460905; RX PubMed=23601657; RX PubMed=24094812; RX PubMed=24176112; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25960936; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=30894373; RX PubMed=31068700; WW Info; LINCS; ICBP43; https://lincs.hms.harvard.edu/resources/reagents/icbp43/ WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255 WW Provider; UT Southwestern; -; https://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: ICBP43 breast cancer cell line panel. CC Part of: JWGray breast cancer cell line panel. CC Part of: MD Anderson Cell Lines Project. CC Population: Caucasian. CC Doubling time: 212.49 hours (JWGray panel). CC HLA typing: A*23:05,68:01; B*27:34,51:12; C*02:02,15:02; DQA1*05:02,01:02; DQB1*03:09,06:02; DRB1*11:01,03:17 (PubMed=25960936). CC HLA typing: A*32:01,32:01; B*27:07,27:07; C*15:02,15:02; DQA1*05:02,03:02; DQB1*03:04,03:04; DRB1*04:05,04:05 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (Cosmic-CLP=1290906; DepMap=ACH-000725). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr284Argfs*21 (c.851_852delCA) (p.R283fs, c.849_850del2); Zygosity=Heterozygous (Cosmic-CLP=1290906; DepMap=ACH-000725). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; miRNA profiling; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=2.66%; Native American=0%; East Asian, North=3.54%; East Asian, South=0%; South Asian=0%; European, North=58.19%; European, South=35.61% (PubMed=30894373). CC Miscellaneous: Direct author submission of STR profile from Girard, Luc & Gazdar, Adi F. CC Derived from site: In situ; Breast; UBERON=UBERON_0000310. ST Source(s): ATCC=CRL-2316; Cosmic-CLP=1290906; Direct_author_submission; KCLB=9S0202; PubMed=25877200 ST Amelogenin: X ST CSF1PO: 10 ST D13S317: 8,9 ST D16S539: 13 ST D18S51: 17 ST D19S433: 14 ST D21S11: 26 ST D2S1338: 20,23 ST D3S1358: 16 ST D5S818: 11,13 ST D7S820: 8,12 ST D8S1179: 13,15 (ATCC=CRL-2316) ST D8S1179: 15 (PubMed=25877200) ST FGA: 24 ST Penta D: 12,15 ST Penta E: 8 ST TH01: 6 ST TPOX: 8,9 ST vWA: 16 DI NCIt; C4017; Breast ductal carcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 82Y CA Cancer cell line DT Created: 04-04-12; Last updated: 14-08-25; Version: 44 // RX PubMed=9833771; DOI=10.1002/(SICI)1097-0215(19981209)78:6<766::AID-IJC15>3.0.CO;2-L; RA Gazdar, Adi F. RA Kurvari, Venkatesh RA Virmani, Arvind K. RA Gollahon, Lauren S. RA Sakaguchi, Masahiro RA Westerfield, Max RA Kodagoda, Dulmini R. RA Stasny, Victor RA Cunningham, H. Thomas RA Wistuba, Ignacio Ivan RA Tomlinson, Gail E. RA Tonk, Vijay RA Ashfaq, Raheela RA Leitch, A. Marilyn RA Minna, John D. RA Shay, Jerry W. RT "Characterization of paired tumor and non-tumor cell lines established RT from patients with breast cancer."; RL Int. J. Cancer 78:766-774(1998). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=23601657; DOI=10.1186/bcr3415; PMCID=PMC3672661; RA Riaz, Muhammad RA van Jaarsveld, Marijn T.M. RA Hollestelle, Antoinette RA Prager-van der Smissen, Wendy J.C. RA Heine, Anouk A.J. RA Boersma, Antonius W.M. RA Liu, Jing-Jing RA Helmijr, Jean C.A. RA Ozturk, Bahar RA Smid, Marcel RA Wiemer, Erik A.C. RA Foekens, John A. RA Martens, John W.M. RT "miRNA expression profiling of 51 human breast cancer cell lines RT reveals subtype and driver mutation-specific miRNAs."; RL Breast Cancer Res. 15:R33.1-R33.17(2013). // RX PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590; RA Daemen, Anneleen RA Griffith, Obi L. RA Heiser, Laura M. RA Wang, Nicholas J. RA Enache, Oana M. RA Sanborn, Zachary RA Pepin, Francois RA Durinck, Steffen RA Korkola, James E. RA Griffith, Malachi RA Hur, Joe S. RA Huh, Nam RA Chung, Jongsuk RA Cope, Leslie RA Fackler, Mary Jo RA Umbricht, Christopher Benedict RA Sukumar, Saraswati RA Seth, Pankaj RA Sukhatme, Vikas P. RA Jakkula, Lakshmi R. RA Lu, Yi-Ling RA Mills, Gordon B. RA Cho, Raymond J. RA Collisson, Eric A. RA van 't Veer, Laura J. RA Spellman, Paul T. RA Gray, Joe W. RT "Modeling precision treatment of breast cancer."; RL Genome Biol. 14:R110.1-R110.14(2013). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura E. RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310; RA Timmerman, Luika A. RA Holton, Thomas RA Yuneva, Mariia RA Louie, Raymond J. RA Padro, Merce RA Daemen, Anneleen RA Hu, Min RA Chan, Denise A. RA Ethier, Stephen P. RA van 't Veer, Laura J. RA Polyak, Kornelia RA McCormick, Frank RA Gray, Joe W. RT "Glutamine sensitivity analysis identifies the xCT antiporter as a RT common triple-negative breast tumor therapeutic target."; RL Cancer Cell 24:450-465(2013). // RX PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981; RA Boegel, Sebastian RA Lower, Martin RA Bukur, Thomas RA Sahin, Ugur RA Castle, John C. RT "A catalog of HLA type, HLA expression, and neo-epitope candidates in RT human cancer cell lines."; RL OncoImmunology 3:e954893.1-e954893.12(2014). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=11314036; DOI=10.1038/sj.onc.1204211; RA Forgacs, Eva RA Wren, Jonathan D. RA Kamibayashi, Craig RA Kondo, Masashi RA Xu, Xie L. RA Markowitz, Sanford David RA Tomlinson, Gail E. RA Muller, Carolyn Y. RA Gazdar, Adi F. RA Garner, Harold Ray RA Minna, John D. RT "Searching for microsatellite mutations in coding regions in lung, RT breast, ovarian and colorectal cancers."; RL Oncogene 20:1005-1009(2001). // RX PubMed=22414580; DOI=10.1158/0008-5472.CAN-11-3711; RA Geiger, Tamar RA Madden, Stephen F. RA Gallagher, William M. RA Cox, Jurgen RA Mann, Matthias RT "Proteomic portrait of human breast cancer progression identifies RT novel prognostic markers."; RL Cancer Res. 72:2428-2439(2012). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, A. Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521; RA Neve, Richard M. RA Chin, Koei RA Fridlyand, Jane RA Yeh, Jennifer RA Baehner, Frederick L. RA Fevr, Tea RA Clark, Laura RA Bayani, Nora RA Coppe, Jean-Philippe RA Tong, Frances RA Speed, Terry RA Spellman, Paul T. RA DeVries, Sandy RA Lapuk, Anna RA Wang, Nick J. RA Kuo, Wen-Lin RA Stilwell, Jackie L. RA Pinkel, Daniel RA Albertson, Donna G. RA Waldman, Frederic M. RA McCormick, Frank RA Dickson, Robert Brent RA Johnson, Michael D. RA Lippman, Marc E. RA Ethier, Stephen P. RA Gazdar, Adi F. RA Gray, Joe W. RT "A collection of breast cancer cell lines for the study of RT functionally distinct cancer subtypes."; RL Cancer Cell 10:515-527(2006). // RX PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084; RA Kao, Jessica RA Salari, Keyan RA Bocanegra, Melanie RA Choi, Yoon-La RA Girard, Luc RA Gandhi, Jeet RA Kwei, Kevin A. RA Hernandez-Boussard, Tina RA Wang, Pei RA Gazdar, Adi F. RA Minna, John D. RA Pollack, Jonathan R. RT "Molecular profiling of breast cancer cell lines defines relevant RT tumor models and provides a resource for cancer gene discovery."; RL PLoS ONE 4:e6146.1-e6146.16(2009). //