ID   DERL-2
AC   CVCL_2016
SY   DERL2; DERL-NK2
DR   CLO; CLO_0037049
DR   BioSample; SAMN03473525
DR   cancercelllines; CVCL_2016
DR   Cell_Model_Passport; SIDM01509
DR   DepMap; ACH-001057
DR   DSMZ; ACC-531
DR   DSMZCellDive; ACC-531
DR   GEO; GSM1374460
DR   LINCS_LDP; LCL-1116
DR   Wikidata; Q54830978
RX   PubMed=10800166;
RX   PubMed=11587224;
RX   PubMed=28122867;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: 72 hours (PubMed=11587224); ~60 hours (DSMZ=ACC-531).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): DSMZ=ACC-531; PubMed=11587224
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 11,12
ST   D16S539: 10,11
ST   D18S51: 14
ST   D19S433: 13,15
ST   D21S11: 29,30
ST   D2S1338: 23,24
ST   D3S1358: 14,15
ST   D5S818: 10,11
ST   D7S820: 11,12
ST   D8S1179: 13,14
ST   FGA: 20,22 (DSMZ=ACC-531)
ST   FGA: 21,22 (PubMed=11587224)
ST   Penta D: 11,13
ST   Penta E: 11,14
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 17,19
DI   NCIt; C8459; Hepatosplenic T-cell lymphoma
DI   ORDO; Orphanet_86882; Hepatosplenic T-cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_2017 ! DERL-7
SX   Male
AG   30Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 25
//
RX   PubMed=11587224; DOI=10.1038/sj.leu.2402239;
RA   Di Noto, Rosa
RA   Pane, Fabrizio
RA   Camera, Andrea
RA   Luciano, Luigia
RA   Barone, Maria Vittoria
RA   Lo Pardo, Catia
RA   Boccuni, Piernicola
RA   Intrieri, Mariano
RA   Izzo, Barbara
RA   Villa, Maria Rosaria
RA   Macri, M.
RA   Rotoli, Bruno
RA   Sacchetti, Lucia
RA   Salvatore, Francesco
RA   Del Vecchio, Luigi
RT   "Characterization of two novel cell lines, DERL-2 (CD56+/CD3+/Tcry5+)
RT   and DERL-7 (CD56+/CD3-/TCRgammadelta-), derived from a single patient
RT   with CD56+ non-Hodgkin's lymphoma.";
RL   Leukemia 15:1641-1649(2001).
//
RX   PubMed=10800166;
RA   Camera, Andrea
RA   Pezzullo, Luca
RA   Villa, Maria Rosaria
RA   Luciano, Luigia
RA   Pane, Fabrizio
RA   Izzo, Barbara
RA   Boccuni, Piernicola
RA   Di Noto, Rosa
RA   Del Vecchio, Luigi
RA   Salvatore, Francesco
RA   Rotoli, Bruno
RT   "Coexistence of two distinct cell populations (CD56(+)TcRgammadelta(+)
RT   and CD56(+)TcRgammadelta(-)) in a case of aggressive CD56(+)
RT   lymphoma/leukemia.";
RL   Haematologica 85:496-501(2000).
//
RX   PubMed=28122867; DOI=10.1158/2159-8290.CD-16-0330; PMCID=PMC5402251;
RA   McKinney, Matthew
RA   Moffitt, Andrea B.
RA   Gaulard, Philippe
RA   Travert, Marion
RA   de Leval, Laurence
RA   Nicolae, Alina
RA   Raffeld, Mark
RA   Jaffe, Elaine Sarkin
RA   Pittaluga, Stefania
RA   Xi, Li-Qiang
RA   Heavican, Tayla
RA   Iqbal, Javeed
RA   Belhadj, Karim
RA   Delfau-Larue, Marie-Helene
RA   Fataccioli, Virginie
RA   Czader, Magdalena B.
RA   Lossos, Izidore S.
RA   Chapman-Fredricks, Jennifer Rose
RA   Richards, Kristy L.
RA   Fedoriw, Yuri
RA   Ondrejka, Sarah L.
RA   Hsi, Eric Darryl
RA   Low, Lawrence
RA   Weisenburger, Dennis D.
RA   Chan, Wing-Chung
RA   Mehta-Shah, Neha
RA   Horwitz, Steven
RA   Bernal-Mizrachi, Leon
RA   Flowers, Christopher Robert
RA   Beaven, Anne W.
RA   Parihar, Mayur
RA   Baseggio, Lucile
RA   Parrens, Marie
RA   Moreau, Anne
RA   Sujobert, Pierre
RA   Pilichowska, Monika
RA   Evens, Andrew M.
RA   Chadburn, Amy
RA   Au-Yeung, Rex Kwok-Him
RA   Srivastava, Gopesh
RA   Choi, William Wai-Lap
RA   Goodlad, John R.
RA   Aurer, Igor
RA   Basic-Kinda, Sandra
RA   Gascoyne, Randy D.
RA   Davis, Nicholas S.
RA   Li, Guo-Jie
RA   Zhang, Jenny
RA   Rajagopalan, Deepthi
RA   Reddy, Anupama
RA   Love, Cassandra L.
RA   Levy, Shawn
RA   Zhuang, Yuan
RA   Datta, Jyotishka
RA   Dunson, David Brian
RA   Dave, Sandeep S.
RT   "The genetic basis of hepatosplenic T-cell lymphoma.";
RL   Cancer Discov. 7:369-379(2017).
//