ID   LPC4p
AC   CVCL_1Y56
DR   Cosmic; 947637
DR   Cosmic; 2649492
DR   Wikidata; Q54902974
RX   PubMed=9892110;
RX   PubMed=15126341;
RX   PubMed=15688027;
CC   Sequence variation: Mutation; HGNC; 6770; SMAD4; Simple; p.Tyr162fs*3; Zygosity=Hemizygous (PubMed=9892110).
CC   Omics: Array-based CGH.
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C3850; Pancreatic carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   75Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 29-06-23; Version: 8
//
RX   PubMed=9892110; DOI=10.1002/(SICI)1098-2264(199901)24:1<62::AID-GCC9>3.0.CO;2-4;
RA   Jonson T., Gorunova L., Dawiskiba S., Andren-Sandberg A., Stenman G.,
RA   ten Dijke P., Johansson B., Hoglund M.;
RT   "Molecular analyses of the 15q and 18q SMAD genes in pancreatic
RT   cancer.";
RL   Genes Chromosomes Cancer 24:62-71(1999).
//
RX   PubMed=15126341; DOI=10.1158/0008-5472.CAN-03-3159;
RA   Heidenblad M., Schoenmakers E.F.P.M., Jonson T., Gorunova L.,
RA   Veltman J.A., van Kessel A.G., Hoglund M.;
RT   "Genome-wide array-based comparative genomic hybridization reveals
RT   multiple amplification targets and novel homozygous deletions in
RT   pancreatic carcinoma cell lines.";
RL   Cancer Res. 64:3052-3059(2004).
//
RX   PubMed=15688027; DOI=10.1038/sj.onc.1208383;
RA   Heidenblad M., Lindgren D., Veltman J.A., Jonson T., Mahlamaki E.H.,
RA   Gorunova L., van Kessel A.G., Schoenmakers E.F.P.M., Hoglund M.;
RT   "Microarray analyses reveal strong influence of DNA copy number
RT   alterations on the transcriptional patterns in pancreatic cancer:
RT   implications for the interpretation of genomic amplifications.";
RL   Oncogene 24:1794-1801(2005).
//