ID   LPC1p
AC   CVCL_1Y53
DR   Cosmic; 947634
DR   Cosmic; 2649489
DR   Wikidata; Q54902963
RX   PubMed=9892110;
RX   PubMed=15126341;
RX   PubMed=15688027;
CC   Sequence variation: Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=9892110).
CC   Omics: Variations; Array-based CGH.
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C207229; Pancreatic carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 10-04-25; Version: 12
//
RX   PubMed=9892110; DOI=10.1002/(SICI)1098-2264(199901)24:1<62::AID-GCC9>3.0.CO;2-4;
RA   Jonson, Tord
RA   Gorunova, Ludmila
RA   Dawiskiba, Sigmund
RA   Andren-Sandberg, Ake
RA   Stenman, Goran
RA   ten Dijke, Peter
RA   Johansson, Bertil
RA   Hoglund, Mattias
RT   "Molecular analyses of the 15q and 18q SMAD genes in pancreatic
RT   cancer.";
RL   Genes Chromosomes Cancer 24:62-71(1999).
//
RX   PubMed=15688027; DOI=10.1038/sj.onc.1208383;
RA   Heidenblad, Markus
RA   Lindgren, David
RA   Veltman, Joris Andre
RA   Jonson, Tord
RA   Mahlamaki, Eija H.
RA   Gorunova, Ludmila
RA   van Kessel, Ad Geurts
RA   Schoenmakers, Eric F.P.M.
RA   Hoglund, Mattias
RT   "Microarray analyses reveal strong influence of DNA copy number
RT   alterations on the transcriptional patterns in pancreatic cancer:
RT   implications for the interpretation of genomic amplifications.";
RL   Oncogene 24:1794-1801(2005).
//
RX   PubMed=15126341; DOI=10.1158/0008-5472.CAN-03-3159;
RA   Heidenblad, Markus
RA   Schoenmakers, Eric F.P.M.
RA   Jonson, Tord
RA   Gorunova, Ludmila
RA   Veltman, Joris Andre
RA   van Kessel, Ad Geurts
RA   Hoglund, Mattias
RT   "Genome-wide array-based comparative genomic hybridization reveals
RT   multiple amplification targets and novel homozygous deletions in
RT   pancreatic carcinoma cell lines.";
RL   Cancer Res. 64:3052-3059(2004).
//