ID   DT40-GRAP(-/-)
AC   CVCL_1U33
SY   GRAP-/- DT40; Grap^(-) DT40
DR   CLO; CLO_0051480
DR   RCB; RCB1498
DR   Wikidata; Q54831483
RX   PubMed=9763608;
CC   Group: Bird cell line.
CC   Knockout cell: Method=Targeted integration; CGNC; 50277; GRAPL.
CC   Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
CC   Cell type: B-cell; CL=CL_0000236.
CC   Breed/subspecies: Hy-Line SC.
DI   NCIt; C134556; Chicken bursal lymphoma
OX   NCBI_TaxID=9031; ! Gallus gallus (Chicken)
HI   CVCL_0249 ! DT40
SX   Female
AG   1D
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 10-09-24; Version: 12
//
RX   PubMed=9763608; DOI=10.1084/jem.188.7.1287; PMCID=PMC2212492;
RA   Hashimoto, Ari
RA   Okada, Hidetaka
RA   Jiang, Ai-Min
RA   Kurosaki, Mari
RA   Greenberg, Steven
RA   Clark, Edward A.
RA   Kurosaki, Tomohiro
RT   "Involvement of guanosine triphosphatases and phospholipase C-gamma2
RT   in extracellular signal-regulated kinase, c-Jun NH2-terminal kinase,
RT   and p38 mitogen-activated protein kinase activation by the B cell
RT   antigen receptor.";
RL   J. Exp. Med. 188:1287-1295(1998).
//