ID   NP-2/CD4/GPR1
AC   CVCL_1R30
SY   NP-2/CD4/EcoVR/GPR1
DR   cancercelllines; CVCL_1R30
DR   RCB; RCB5312
DR   Wikidata; Q54930954
RX   DOI=10.2974/kmj.62.1;
RX   PubMed=11112502;
RX   PubMed=18577234;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1678; CD4.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4463; CMKLR2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1R18 ! NP-2/CD4
SX   Male
AG   63Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 14-08-25; Version: 15
//
RX   DOI=10.2974/kmj.62.1;
RA   Hoshino, Hiroo
RT   "The NP-2 cell system for analyses of the coreceptor usage of human
RT   and simian immunodeficiency viruses.";
RL   Kitakanto Med. J. 62:1-14(2012).
//
RX   PubMed=18577234; DOI=10.1186/1742-4690-5-52; PMCID=PMC2453146;
RA   Shimizu, Nobuaki
RA   Tanaka, Atsushi
RA   Mori, Takahisa
RA   Ohtsuki, Takahiro
RA   Hoque, Aliful
RA   Jinno-Oue, Atsushi
RA   Apichartpiyakul, Chatchawann
RA   Kusagawa, Shigeru
RA   Takebe, Yutaka
RA   Hoshino, Hiroo
RT   "A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for
RT   primary isolates of human immunodeficiency virus.";
RL   Retrovirology 5:52.1-52.14(2008).
//
RX   PubMed=11112502; DOI=10.1006/viro.2000.0623;
RA   Liu, Hui-Yu
RA   Soda, Yasushi
RA   Shimizu, Nobuaki
RA   Haraguchi, Yuji
RA   Jinno-Oue, Atsushi
RA   Takeuchi, Yasuhiro
RA   Hoshino, Hiroo
RT   "CD4-dependent and CD4-independent utilization of coreceptors by human
RT   immunodeficiency viruses type 2 and simian immunodeficiency viruses.";
RL   Virology 278:276-288(2000).
//