ID   NP-2/CD4
AC   CVCL_1R18
SY   NP2/CD4; NP2-CD4; NP-2/CD4/EcoVR
DR   cancercelllines; CVCL_1R18
DR   RCB; RCB5305
DR   Wikidata; Q54930945
RX   DOI=10.2974/kmj.62.1;
RX   PubMed=10329384;
RX   PubMed=11112502;
RX   PubMed=18577234;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: HGNC; 1678; CD4.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1R15 ! NP-2
SX   Male
AG   63Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 05-10-23; Version: 10
//
RX   DOI=10.2974/kmj.62.1;
RA   Hoshino H.;
RT   "The NP-2 cell system for analyses of the coreceptor usage of human
RT   and simian immunodeficiency viruses.";
RL   Kitakanto Med. J. 62:1-14(2012).
//
RX   PubMed=10329384; DOI=10.1006/bbrc.1999.0633;
RA   Soda Y., Shimizu N., Jinno A., Liu H.-Y., Kanbe K., Kitamura T.,
RA   Hoshino H.;
RT   "Establishment of a new system for determination of coreceptor usages
RT   of HIV based on the human glioma NP-2 cell line.";
RL   Biochem. Biophys. Res. Commun. 258:313-321(1999).
//
RX   PubMed=11112502; DOI=10.1006/viro.2000.0623;
RA   Liu H.-Y., Soda Y., Shimizu N., Haraguchi Y., Jinno A., Takeuchi Y.,
RA   Hoshino H.;
RT   "CD4-dependent and CD4-independent utilization of coreceptors by human
RT   immunodeficiency viruses type 2 and simian immunodeficiency viruses.";
RL   Virology 278:276-288(2000).
//
RX   PubMed=18577234; DOI=10.1186/1742-4690-5-52;
RA   Shimizu N., Tanaka A., Mori T., Ohtsuki T., Hoque A., Jinno-Oue A.,
RA   Apichartpiyakul C., Kusagawa S., Takebe Y., Hoshino H.;
RT   "A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for
RT   primary isolates of human immunodeficiency virus.";
RL   Retrovirology 5:52.1-52.14(2008).
//