ID   NP-2
AC   CVCL_1R15
SY   NP 2; Case 4; NB3911
DR   cancercelllines; CVCL_1R15
DR   Cell_Model_Passport; SIDM01822
DR   DepMap; ACH-001608
DR   JCRB; JCRB1566
DR   RCB; RCB4498
DR   Wikidata; Q54930940
RX   CelloPub=CLPUB00260;
RX   DOI=10.2974/kmj.62.1;
RX   PubMed=8878451;
RX   PubMed=10551321;
RX   PubMed=18415661;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Doubling time: 36 hours (Note=At 145th passage) (CelloPub=CLPUB00260).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Unspecified (PubMed=8878451).
CC   Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
ST   Source(s): DepMap=ACH-001608; JCRB=JCRB1566
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 10,12
ST   D16S539: 9,10,11
ST   D18S51: 13,15
ST   D21S11: 29
ST   D3S1358: 15,16
ST   D5S818: 11
ST   D7S820: 11
ST   D8S1179: 14,17
ST   FGA: 23
ST   Penta D: 12
ST   Penta E: 11
ST   TH01: 6
ST   TPOX: 8,11
ST   vWA: 16
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   63Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 02-05-24; Version: 17
//
RX   CelloPub=CLPUB00260;
RA   Yamazaki K.;
RT   "Tumorigenicity of established human glioma cell lines in lasat and
RT   nude mice.";
RL   Neuropathology 3:29-38(1982).
//
RX   DOI=10.2974/kmj.62.1;
RA   Hoshino H.;
RT   "The NP-2 cell system for analyses of the coreceptor usage of human
RT   and simian immunodeficiency viruses.";
RL   Kitakanto Med. J. 62:1-14(2012).
//
RX   PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x;
RA   Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K.,
RA   Washiyama K., Kumanishi T.;
RT   "A comparative study of glioma cell lines for p16, p15, p53 and p21
RT   gene alterations.";
RL   Jpn. J. Cancer Res. 87:900-907(1996).
//
RX   PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x;
RA   Zhang S.-J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R.,
RA   Washiyama K., Kumanishi T.;
RT   "Rare-type mutations of MMAC1 tumor suppressor gene in human glioma
RT   cell lines and their tumors of origin.";
RL   Jpn. J. Cancer Res. 90:934-941(1999).
//
RX   PubMed=18415661; DOI=10.1007/s10014-007-0226-0;
RA   Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H.,
RA   Washiyama K., Kumanishi T., Uematsu Y., Itakura T.;
RT   "Frequent and variable abnormalities in p14 tumor suppressor gene in
RT   glioma cell lines.";
RL   Brain Tumor Pathol. 25:9-17(2008).
//