AC   CVCL_1Q81
DR   BioSample; SAMN03151810
DR   Wikidata; Q54938512
RX   PubMed=17350682;
RX   PubMed=17917092;
RX   PubMed=19344951;
CC   Problematic cell line: Contaminated. Shown to be a K-562 derivative (PubMed=19344951).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00379.
CC   Population: Caucasian.
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C9110; Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0004 ! K-562
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 02-05-24; Version: 20
RX   PubMed=17350682; DOI=10.1016/j.leukres.2007.01.012;
RA   Bogdanovic G., Jurisic V., Kraguljac N., Mrdjanovic J., Jakimov D.,
RA   Krtolica K., Krajnovic M., Magic Z., Stojiljkovic B., Andrijevic L.,
RA   Srdic-Rajic T., Baltic M., Popovic S.;
RT   "Characteristics of novel myeloid precursor cell line, PC-MDS,
RT   established from a bone marrow of the patient with therapy-related
RT   myelodysplastic syndrome.";
RL   Leuk. Res. 31:1097-1105(2007).
RX   PubMed=17917092; DOI=10.1007/s12032-007-0031-y;
RA   Bogdanovic G., Jakimov D., Stojiljkovic B., Jurisic V.;
RT   "The cell growth, morphology and immunocytochemistry of novel cell
RT   line established from a bone marrow of the patient with therapy-related
RT   myelodysplastic syndrome, entitled PC-MDS.";
RL   Med. Oncol. 24:419-424(2007).
RX   PubMed=19344951; DOI=10.1016/j.leukres.2009.03.005;
RA   Drexler H.G., Dirks W.G., MacLeod R.A.F.;
RT   "Many are called MDS cell lines: one is chosen.";
RL   Leuk. Res. 33:1011-1016(2009).