ID   F-137
AC   CVCL_1Q45
SY   F 137; F137
DR   cancercelllines; CVCL_1Q45
DR   Wikidata; Q54833024
RX   PubMed=1180485;
RX   PubMed=4736620;
RX   PubMed=5287057;
RX   PubMed=18623934;
CC   Problematic cell line: Contaminated. Shown to be a Jiyoye derivative (PubMed=4736620). Originally thought to originate from the lymph node of a male chronic lymphocytic leukemia patient.
CC   Population: African; Nigerian.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys132Gln (c.394A>C); ClinVar=VCV000376628; Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1317 ! Jiyoye
SX   Male
AG   7Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 02-05-24; Version: 17
RX   PubMed=1180485; DOI=10.1111/j.1469-1809.1975.tb00105.x;
RA   Arthur E., Steel C.M., Evans H.J., Povey S., Watson B., Harris H.;
RT   "Genetic studies on human lymphoblastoid cell lines: isozyme and
RT   cytogenetic heterogeneity in a cell line, with evidence for
RT   localization of the Pep A locus in man.";
RL   Ann. Hum. Genet. 39:33-42(1975).
RX   PubMed=4736620; DOI=10.1111/j.1469-1809.1973.tb00588.x;
RA   Povey S., Gardiner S.E., Watson B., Mowbray S., Harris H., Arthur E.,
RA   Steel C.M., Blenkinsop C., Evans H.J.;
RT   "Genetic studies on human lymphoblastoid lines: isozyme analysis on
RT   cell lines from forty-one different individuals and on mutants
RT   produced following exposure to a chemical mutagen.";
RL   Ann. Hum. Genet. 36:247-266(1973).
RX   PubMed=5287057; DOI=10.1093/jnci/47.6.1203;
RA   Steel C.M., McBeath S., O'Riordan M.L.;
RT   "Human lymphoblastoid cell lines. II. Cytogenetic studies.";
RL   J. Natl. Cancer Inst. 47:1203-1214(1971).
RX   PubMed=18623934; DOI=10.1093/jnci/39.4.745;
RA   Jensen E.M., Korol W., Dittmar S.L., Medrek T.J.;
RT   "Virus containing lymphocyte cultures from cancer patients.";
RL   J. Natl. Cancer Inst. 39:745-754(1967).