ID   LuSIV
AC   CVCL_1H04
DR   BEI_Resources; ARP-5460
DR   Wikidata; Q54903275
RX   PubMed=10915601;
WW   Info; IdeaConnection; -; https://www.ideaconnection.com/patents/5827-LuSIV-Cells-a-Highly-Sensitive-Detection-System-for-I.html
CC   Characteristics: Transfected with a construct containing firefly luciferase under the control of the SIVmac239 LTR. Activation requires the viral transactivating protein Tat to drive expression of the luciferase reporter gene from the LTR (PubMed=10915601).
CC   Virology: Can be used for the quantitative measurement of HIV/SIV infection within a single replication cycle (PubMed=10915601).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_7904 ! T1
CA   Hybrid cell line
DT   Created: 08-07-15; Last updated: 10-04-25; Version: 9
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RX   PubMed=10915601; DOI=10.1006/viro.2000.0431;
RA   Roos J.W., Maughan M.F., Liao Z.-H., Hildreth J.E.K., Clements J.E.;
RT   "LuSIV cells: a reporter cell line for the detection and quantitation
RT   of a single cycle of HIV and SIV replication.";
RL   Virology 273:307-315(2000).
//