ID   HOS-CD4-CCR4
AC   CVCL_1D97
SY   HOS.CD4.CCR4
DR   BEI_Resources; ARP-3317
DR   cancercelllines; CVCL_1D97
DR   Wikidata; Q54890167
RX   PubMed=8649511;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1605; CCR4.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1678; CD4.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
CC   Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_W650 ! HOS-CD4
SX   Female
AG   13Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 14-08-25; Version: 16
//
RX   PubMed=8649511; DOI=10.1038/381661a0;
RA   Deng, Hong-Kui
RA   Liu, Rong
RA   Ellmeier, Wilfried
RA   Choe, Sunny
RA   Unutmaz, Derya
RA   Burkhart, Michael
RA   Di Marzio, Paola
RA   Marmon, Shoshana
RA   Sutton, Richard E.
RA   Hill, C. Mark
RA   Davis, Craig B.
RA   Peiper, Stephen Chalmer
RA   Schall, Thomas J.
RA   Littman, Dan Rudolf
RA   Landau, Nathaniel R.
RT   "Identification of a major co-receptor for primary isolates of
RT   HIV-1.";
RL   Nature 381:661-666(1996).
//