ID   CL-38
AC   CVCL_1981
SY   CL 38; CL38
DR   DSMZ; ACC-621
DR   DSMZCellDive; ACC-621
DR   Wikidata; Q54813480
RX   CelloPub=CLPUB00363;
RX   PubMed=2684400;
RX   PubMed=2720663;
RX   PubMed=2895109;
RX   PubMed=9288899;
CC   Doubling time: ~30-40 hours (DSMZ=ACC-621).
CC   Transformant: ChEBI; CHEBI_34873; N-nitrosodiethylamine (Diethylnitrosamine; DEN).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: Wistar-AF/Han.
DI   NCIt; C60416; Rat hepatocellular carcinoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 13
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RX   CelloPub=CLPUB00363;
RA   Kerler R.;
RT   "In vivo rats liver cells induced by chemical carcinogens in vitro:
RT   establishment, cytogenetic and cell biology characterization of
RT   immortalized and neoplastically transformed cell lines.";
RL   Thesis PhD (2000); Ludwig Maximilians University of Munich; Munich; Germany.
//
RX   PubMed=2684400;
RA   Suchy B.K., Sarafoff M., Kerler R., Rabes H.M.;
RT   "Amplification, rearrangements, and enhanced expression of c-myc in
RT   chemically induced rat liver tumors in vivo and in vitro.";
RL   Cancer Res. 49:6781-6787(1989).
//
RX   PubMed=2720663;
RA   Holecek B.-U., Kerler R., Rabes H.M.;
RT   "Chromosomal analysis of a diethylnitrosamine-induced tumorigenic and
RT   a nontumorigenic rat liver cell line.";
RL   Cancer Res. 49:3024-3028(1989).
//
RX   PubMed=2895109; DOI=10.1007/BF00417823;
RA   Kerler R., Rabes H.M.;
RT   "Preneoplastic rat liver cells in vitro: slow progression without
RT   promoters, hormones, or growth factors.";
RL   J. Cancer Res. Clin. Oncol. 114:113-123(1988).
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RX   PubMed=9288899; DOI=10.1111/j.1432-1033.1997.t01-1-00792.x;
RA   Zeindl-Eberhart E., Jungblut P.R., Otto A., Kerler R., Rabes H.M.;
RT   "Further characterization of a rat hepatoma-derived
RT   aldose-reductase-like protein -- organ distribution and modulation in
RT   vitro.";
RL   Eur. J. Biochem. 247:792-800(1997).
//