ID   TMM
AC   CVCL_1894
DR   CLO; CLO_0009376
DR   CLDB; cl4533
DR   BioSample; SAMN03151631
DR   BioSample; SAMN03473406
DR   DSMZ; ACC-95
DR   DSMZCellDive; ACC-95
DR   Wikidata; Q54972699
RX   PubMed=3478106;
RX   PubMed=10516762;
RX   PubMed=20143388;
RX   PubMed=20454443;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Misclassified. Originally thought to be a leukemia cell line from a patient with myelodysplastic syndrome but is a B-lymphoblastoid cell line (PubMed=10516762; PubMed=20143388).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00279.
CC   Doubling time: ~20-40 hours (DSMZ=ACC-95).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
ST   Source(s): DSMZ=ACC-95
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 12,14
ST   D16S539: 10,12
ST   D18S51: 13,16
ST   D19S433: 14,15
ST   D21S11: 29,32.2
ST   D2S1338: 18,19
ST   D3S1358: 15,18
ST   D5S818: 11
ST   D7S820: 10,11
ST   D8S1179: 11,13
ST   FGA: 17.3,23
ST   Penta D: 11,12
ST   Penta E: 7
ST   TH01: 8,9.3
ST   TPOX: 8,9
ST   vWA: 14,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 21
//
RX   PubMed=3478106; DOI=10.1182/blood.V70.5.1665.1665;
RA   McCarty, Todd M.
RA   Rajaraman, Sirinivasan
RA   Elder, Frederick F.B.
RA   Gadson, Preston Foster Jr.
RA   Thompson, E. Brad
RT   "Establishment and characterization of a human myeloid cell line from
RT   Philadelphia chromosome-negative myeloblastic leukemia arising in a
RT   patient with myelodysplastic syndrome.";
RL   Blood 70:1665-1672(1987).
//
RX   PubMed=10516762; DOI=10.1038/sj.leu.2401510;
RA   Drexler, Hans Gunther
RA   Dirks, Wilhelm Gerhard
RA   MacLeod, Roderick A.F.
RT   "False human hematopoietic cell lines: cross-contaminations and
RT   misinterpretations.";
RL   Leukemia 13:1601-1607(1999).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis, Amanda
RA   Theodosopoulos, George
RA   Atkin, Isobel
RA   Drexler, Hans Gunther
RA   Kohara, Arihiro
RA   MacLeod, Roderick A.F.
RA   Masters, John R.W.
RA   Nakamura, Yukio
RA   Reid, Yvonne A.
RA   Reddel, Roger Robert
RA   Freshney, Robert Ian
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=20454443; DOI=10.1155/2010/904767; PMCID=PMC2861168;
RA   Uphoff, Cord C.
RA   Denkmann, Sabine A.
RA   Steube, Klaus G.
RA   Drexler, Hans Gunther
RT   "Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human
RT   and other primate cell lines.";
RL   J. Biomed. Biotechnol. 2010:904767.1-904767.23(2010).
//