ID   UPCI-SCC-029A
AC   CVCL_1855
SY   UPCI-SCC-29A; UPCI:SCC029A; UPCISCC029A; UPCI-SCC-029B; UPCI:SCC029B; UPCI:SCC029; SCC029
DR   BioSample; SAMN03473472
DR   cancercelllines; CVCL_1855
DR   DepMap; ACH-001691
DR   DSMZ; ACC-659
DR   DSMZCellDive; ACC-659
DR   IARC_TP53; 18351
DR   Wikidata; Q54991569
RX   PubMed=12872257;
RX   PubMed=17112776;
RX   PubMed=17681875;
RX   PubMed=24142626;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Caucasian.
CC   Doubling time: ~60 hours (DSMZ=ACC-659).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg280Thr (c.839G>C); ClinVar=VCV000012368; Zygosity=Heterozygous (PubMed=12872257; DepMap=ACH-001691).
CC   Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956.
ST   Source(s): DSMZ=ACC-659
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 11,12
ST   D18S51: 14,18.2
ST   D19S433: 14,15
ST   D21S11: 29,30
ST   D2S1338: 17,25
ST   D3S1358: 14,17
ST   D5S818: 11
ST   D7S820: 8,9
ST   D8S1179: 12,14
ST   FGA: 22,23
ST   Penta D: 13
ST   Penta E: 10,12
ST   TH01: 6,7
ST   TPOX: 9,11
ST   vWA: 14,17
DI   NCIt; C4833; Oral cavity squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   84Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 19
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M.,
RA   Ishwad C.S., Jarvik J.W.;
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003;
RA   Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W.,
RA   Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.;
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//
RX   PubMed=24142626; DOI=10.1002/gcc.22115;
RA   Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W.,
RA   Vlad A., Gollin S.M.;
RT   "Upregulation of the ATR-CHEK1 pathway in oral squamous cell
RT   carcinomas.";
RL   Genes Chromosomes Cancer 53:25-37(2014).
//