ID   Namalwa.KN2
AC   CVCL_1840
SY   NAMALWA.KN2; Namalwa KN2; KN2
DR   CLO; CLO_0007942
DR   CLDB; cl3640
DR   BioSample; SAMN03473433
DR   cancercelllines; CVCL_1840
DR   DSMZ; ACC-68
DR   DSMZCellDive; ACC-68
DR   Wikidata; Q54907454
RX   PubMed=1339415;
RX   PubMed=2298494;
RX   PubMed=3026962;
RX   PubMed=20454443;
WW   Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=KN2
CC   Population: African; Kenyan.
CC   Virology: Contains 2 integrated copies of EBV genome on chromosome 1.
CC   Virology: Infected by squirrel monkey retrovirus (SMRV) (PubMed=1339415; PubMed=20454443).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): DSMZ=ACC-68
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 12
ST   D16S539: 9
ST   D18S51: 15
ST   D19S433: 14,18
ST   D21S11: 27,28
ST   D2S1338: 17,21
ST   D3S1358: 16
ST   D5S818: 12,13
ST   D7S820: 11
ST   D8S1179: 13,15
ST   FGA: 22
ST   Penta D: 8,13
ST   Penta E: 5,15
ST   TH01: 7,9.3
ST   TPOX: 6,11
ST   vWA: 14
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0067 ! Namalwa
SX   Female
AG   Children
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 26
//
RX   PubMed=3026962; PMCID=PMC1453332;
RA   Guy, Keith
RA   Middleton, Peter Gelder
RA   Docherty, Linda J.M.
RA   De Angelis, C.L.
RA   Steel, Christopher Michael
RT   "MHC class II antigen and immunoglobulin expression in spontaneous
RT   phenotypic variants of the Burkitt's lymphoma cell line Namalwa.";
RL   Immunology 59:603-610(1986).
//
RX   PubMed=1339415; DOI=10.1002/ijc.2910520320;
RA   Middleton, Peter Gelder
RA   Miller, S.
RA   Ross, James A.
RA   Steel, Christopher Michael
RA   Guy, Keith
RT   "Insertion of SMRV-H viral DNA at the c-myc gene locus of a BL cell
RT   line and presence in established cell lines.";
RL   Int. J. Cancer 52:451-454(1992).
//
RX   PubMed=20454443; DOI=10.1155/2010/904767; PMCID=PMC2861168;
RA   Uphoff, Cord C.
RA   Denkmann, Sabine A.
RA   Steube, Klaus G.
RA   Drexler, Hans Gunther
RT   "Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human
RT   and other primate cell lines.";
RL   J. Biomed. Biotechnol. 2010:904767.1-904767.23(2010).
//
RX   PubMed=2298494; DOI=10.1002/ijc.2910450120;
RA   Guy, Keith
RA   Middleton, Peter Gelder
RA   Bansal, Narinder S.
RA   Ross, James A.
RA   Steel, Christopher Michael
RT   "Recurrent mutation of immunoglobulin and c-myc genes and differential
RT   expression of cell surface antigens occur in variant cell lines
RT   derived from a Burkitt lymphoma.";
RL   Int. J. Cancer 45:109-118(1990).
//