ID VMRC-RCW AC CVCL_1790 SY VMRCRCW; Thomas Wirts; Virginia Mason Research Center-Renal Cancer W DR BTO; BTO_0003714 DR CLO; CLO_0050893 DR EFO; EFO_0022457 DR ArrayExpress; E-MTAB-2770 DR BioSample; SAMN03470901 DR BioSample; SAMN03472513 DR BioSample; SAMN10987862 DR cancercelllines; CVCL_1790 DR Cell_Model_Passport; SIDM00318 DR Cosmic; 756014 DR Cosmic; 849370 DR Cosmic-CLP; 1240224 DR DepMap; ACH-000484 DR GDSC; 1240224 DR GEO; GSM827232 DR GEO; GSM887733 DR GEO; GSM888828 DR JCRB; JCRB0813 DR LiGeA; CCLE_018 DR LINCS_LDP; LCL-1759 DR PharmacoDB; VMRCRCW_1658_2019 DR PRIDE; PXD030304 DR Progenetix; CVCL_1790 DR RCB; RCB1963 DR TKG; TKG 0447 DR Wikidata; Q54993288 RX PubMed=9290701; RX PubMed=10929426; RX PubMed=11146448; RX PubMed=20215515; RX PubMed=22460905; RX PubMed=25877200; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28489074; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC From: Bean, Michael A.; Virginia Mason Research Center; Seattle; USA. CC Population: Caucasian. CC Doubling time: ~60 hours (Note=Lot 102398), ~27 hours (Note=Lot 10052009), ~35 hours (Note=Lot 11082016) (JCRB=JCRB0813). CC HLA typing: A*02:01,33:03; B*07:02,18:01; C*04:01,07:06; DQA1*01:02,04:01; DQB1*02:02,02:02; DRB1*11:08,15:02 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=2.21%; Native American=0.43%; East Asian, North=1.64%; East Asian, South=0%; South Asian=1.16%; European, North=69.86%; European, South=24.69% (PubMed=30894373). ST Source(s): Cosmic-CLP=1240224; JCRB=JCRB0813; PubMed=25877200; RCB=RCB1963; TKG=TKG 0447 ST Amelogenin: X,Y (JCRB=JCRB0813; RCB=RCB1963; TKG=TKG 0447) ST Amelogenin: Y (Cosmic-CLP=1240224; PubMed=25877200) ST CSF1PO: 11,12 ST D13S317: 9 ST D16S539: 11,15 ST D18S51: 15,16 ST D19S433: 13 ST D21S11: 32.2,33.2 ST D2S1338: 21,22 ST D3S1358: 18 ST D5S818: 12 ST D7S820: 8,10 ST D8S1179: 12 ST FGA: 21,22 ST Penta D: 9,11 ST Penta E: 11,12 ST TH01: 6,9.3 ST TPOX: 8 ST vWA: 14,15 DI NCIt; C9385; Renal cell carcinoma DI ORDO; Orphanet_217071; Renal cell carcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG Age unspecified CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 32 // RX PubMed=11146448; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1034>3.0.CO;2-S; RA Kondo, Kei-ichi RA Yao, Masahiro RA Kobayashi, Kazuki RA Ota, Shinsuke RA Yoshida, Minoru RA Kaneko, Shigeki RA Baba, Masaya RA Sakai, Naoki RA Kishida, Takeshi RA Kawakami, Satoshi RA Uemura, Hiroji RA Nagashima, Yoji RA Nakatani, Yukio RA Hosaka, Masahiko RT "PTEN/MMAC1/TEP1 mutations in human primary renal-cell carcinomas and RT renal carcinoma cell lines."; RL Int. J. Cancer 91:219-224(2001). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=28489074; DOI=10.1038/ncomms15165; PMCID=PMC5436135; RA Sinha, Rileen RA Winer, Andrew G. RA Chevinsky, Michael Stephen RA Jakubowski, Christopher RA Chen, Ying-Bei RA Dong, Yi-Yu RA Tickoo, Satish K. RA Reuter, Victor E. RA Russo, Paul RA Coleman, Jonathan A. RA Sander, Chris RA Hsieh, James J.-D. RA Hakimi, Abraham Ari RT "Analysis of renal cancer cell lines from two major resources enables RT genomics-guided cell line selection."; RL Nat. Commun. 8:15165.1-15165.10(2017). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=10929426; DOI=10.1007/s002400000103; RA Shintaku, Ichiro RA Kawagoe, Nobutoshi RA Yutani, Shigeru RA Hoshi, Sakuo RA Orikasa, Seiichi RA Yoshizumi, Osamu RA Itoh, Kyogo RT "Expression of the SART1 tumor rejection antigen in renal cell RT carcinoma."; RL Urol. Res. 28:178-184(2000). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D; RA Jia, Li-Qun RA Osada, Motonobu RA Ishioka, Chikashi RA Gamo, Makio RA Ikawa, Shuntaro RA Suzuki, Takao RA Shimodaira, Hideki RA Niitani, Tomohito RA Kudo, Toshio RA Akiyama, Mitoshi RA Kimura, Narimiti RA Matsuo, Mitsuyoshi RA Mizusawa, Hiroshi RA Tanaka, Noriho RA Koyama, Hideki RA Namba, Masayoshi RA Kanamaru, Ryunosuke RA Kuroki, Toshio RT "Screening the p53 status of human cell lines using a yeast functional RT assay."; RL Mol. Carcinog. 19:243-253(1997). //