ID   TGW
AC   CVCL_1771
SY   TOG; TGW-nu; TGW-I-nu; TGW-nu-1
DR   CLO; CLO_0009830
DR   EFO; EFO_0022441
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   BioGRID_ORCS_Cell_line; 1037
DR   BioSample; SAMN03471635
DR   cancercelllines; CVCL_1771
DR   Cell_Model_Passport; SIDM00324
DR   ChEMBL-Cells; CHEMBL3308792
DR   ChEMBL-Targets; CHEMBL1075600
DR   Cosmic; 801749
DR   Cosmic; 910780
DR   Cosmic; 920238
DR   Cosmic; 947703
DR   Cosmic; 1037349
DR   Cosmic; 1099146
DR   Cosmic; 1153801
DR   Cosmic; 2131589
DR   Cosmic-CLP; 910780
DR   DepMap; ACH-001674
DR   EGA; EGAS00001000978
DR   GDSC; 910780
DR   GEO; GSM314028
DR   GEO; GSM333815
DR   GEO; GSM1670542
DR   JCRB; JCRB0618
DR   LINCS_LDP; LCL-1962
DR   Lonza; 1191
DR   PharmacoDB; TGW_1592_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1771
DR   PubChem_Cell_line; CVCL_1771
DR   Wikidata; Q54972266
RX   PubMed=2335222;
RX   PubMed=12210830;
RX   PubMed=15892104;
RX   PubMed=18923524;
RX   PubMed=20164919;
RX   PubMed=27397505;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=35839778;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/t/cell-lines-detail-424.html
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Population: Japanese.
CC   Doubling time: 32 hours (Note=Lot 06012007), ~27 hours (Note=Lot 04172014) (JCRB=JCRB0618).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=71.87%; East Asian, South=26.74%; South Asian=0.97%; European, North=0.42%; European, South=0% (PubMed=30894373).
CC   Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
ST   Source(s): Cosmic-CLP=910780; DepMap=ACH-001674; JCRB=JCRB0618
ST   Amelogenin: X
ST   CSF1PO: 15
ST   D13S317: 8,11
ST   D16S539: 9,13
ST   D18S51: 14
ST   D21S11: 30,33.2
ST   D3S1358: 16
ST   D5S818: 13
ST   D7S820: 12
ST   D8S1179: 14
ST   FGA: 23
ST   Penta D: 9,10
ST   Penta E: 11,12
ST   TH01: 6,7
ST   TPOX: 10,11
ST   vWA: 14,18
DI   NCIt; C4827; Adrenal gland neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1Y11M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 39
CH   CVCL_3180 ! TGW.P3
CH   CVCL_A443 ! TNB1
//
RX   PubMed=18923524; DOI=10.1038/nature07399;
RA   Chen, Yu-Yan
RA   Takita, Junko
RA   Choi, Young Lim
RA   Kato, Motohiro
RA   Ohira, Miki
RA   Sanada, Masashi
RA   Wang, Li-Li
RA   Soda, Manabu
RA   Kikuchi, Akira
RA   Igarashi, Takashi
RA   Nakagawara, Akira
RA   Hayashi, Yasuhide
RA   Mano, Hiroyuki
RA   Ogawa, Seishi
RT   "Oncogenic mutations of ALK kinase in neuroblastoma.";
RL   Nature 455:971-974(2008).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=12210830; DOI=10.1002/jnr.10330;
RA   Yoshida, Shinobu
RA   Narita, Tsutomu
RA   Taga, Takashi
RA   Ohta, Shigeru
RA   Takeuchi, Yoshihiro
RT   "Malignant rhabdoid tumor shows incomplete neural characteristics as
RT   revealed by expression of SNARE complex.";
RL   J. Neurosci. Res. 69:642-652(2002).
//
RX   PubMed=15892104; DOI=10.1002/gcc.20198;
RA   Mosse, Yael P.
RA   Greshock, Joel
RA   Margolin, Adam A.
RA   Naylor, Tara
RA   Cole, Kristina A.
RA   Khazi, Deepa
RA   Hii, George
RA   Winter, Cynthia
RA   Shahzad, Syed
RA   Asziz, Muhammad Usman
RA   Biegel, Jaclyn A.
RA   Weber, Barbara L.
RA   Maris, John Matthew
RT   "High-resolution detection and mapping of genomic DNA alterations in
RT   neuroblastoma.";
RL   Genes Chromosomes Cancer 43:390-403(2005).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=2335222; DOI=10.1016/0014-5793(90)81370-4;
RA   Tsuchida, Yoshiaki
RA   Sekiguchi, Morimasa
RA   Kaneko, Yasuhiko
RA   Kanda, Naotoshi
RT   "Origin of human neuroblastoma cell lines TGW and TNB1.";
RL   FEBS Lett. 263:191-191(1990).
//
RX   PubMed=30971826; DOI=10.1038/s41586-019-1103-9;
RA   Behan, Fiona M.
RA   Iorio, Francesco
RA   Picco, Gabriele
RA   Goncalves, Emanuel
RA   Beaver, Charlotte M.
RA   Migliardi, Giorgia
RA   Santos, Rita
RA   Rao, Yanhua
RA   Sassi, Francesco
RA   Pinnelli, Marika
RA   Ansari, Rizwan
RA   Harper, Sarah
RA   Jackson, David Adam
RA   McRae, Rebecca
RA   Pooley, Rachel
RA   Wilkinson, Piers
RA   van der Meer, Dieudonne J.
RA   Dow, David
RA   Buser-Doepner, Carolyn A.
RA   Bertotti, Andrea
RA   Trusolino, Livio
RA   Stronach, Euan Alexander
RA   Saez-Rodriguez, Julio
RA   Yusa, Kosuke
RA   Garnett, Mathew J.
RT   "Prioritization of cancer therapeutic targets using CRISPR-Cas9
RT   screens.";
RL   Nature 568:511-516(2019).
//