ID TE-15 AC CVCL_1763 SY TE15; Te15 DR BTO; BTO_0004598 DR CLO; CLO_0051370 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR BioSample; SAMN03472042 DR BioSample; SAMN10988301 DR cancercelllines; CVCL_1763 DR Cell_Model_Passport; SIDM00249 DR CGH-DB; 317-1 DR CGH-DB; 9266-4 DR ChEMBL-Cells; CHEMBL3308221 DR ChEMBL-Targets; CHEMBL2366086 DR Cosmic; 753614 DR Cosmic; 923183 DR Cosmic; 983724 DR Cosmic; 1043237 DR Cosmic; 1123332 DR Cosmic; 1612900 DR Cosmic; 2698429 DR Cosmic-CLP; 753614 DR DepMap; ACH-000353 DR EGA; EGAS00001000978 DR GDSC; 753614 DR GEO; GSM887694 DR GEO; GSM888787 DR GEO; GSM1670532 DR IARC_TP53; 6332 DR LiGeA; CCLE_057 DR LINCS_LDP; LCL-1568 DR PharmacoDB; TE15_1580_2019 DR PRIDE; PXD002486 DR PRIDE; PXD030304 DR Progenetix; CVCL_1763 DR PubChem_Cell_line; CVCL_1763 DR RCB; RCB1951 DR TKG; TKG 0266 DR Wikidata; Q54972013 RX PubMed=8509434; RX PubMed=9096669; RX PubMed=9290701; RX PubMed=15172977; RX PubMed=17804709; RX PubMed=20164919; RX PubMed=22460905; RX PubMed=25984343; RX PubMed=27397505; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=35839778; CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Population: Japanese. CC Doubling time: 37 hours (PubMed=25984343). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.560-1G>A; ClinVar=VCV000634769; Zygosity=Unspecified; Note=Splice acceptor mutation (PubMed=9096669). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Phenotyping; shRNA library screening. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0%; Native American=0%; East Asian, North=83.86%; East Asian, South=15.31%; South Asian=0.83%; European, North=0%; European, South=0% (PubMed=30894373). CC Derived from site: In situ; Esophagus; UBERON=UBERON_0001043. ST Source(s): Cosmic-CLP=753614; RCB=RCB1951; TKG=TKG 0266 ST Amelogenin: X ST CSF1PO: 12 ST D13S317: 12 ST D16S539: 9 ST D5S818: 9 ST D7S820: 11 ST TH01: 7 ST TPOX: 9 ST vWA: 15,18 DI NCIt; C4024; Esophageal squamous cell carcinoma DI ORDO; Orphanet_99977; Squamous cell carcinoma of the esophagus OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 58Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 40 // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=8509434; DOI=10.1007/BF01215923; RA Nishihira, Tetsuro RA Hashimoto, Yu RA Katayama, Masafumi RA Mori, Shozo RA Kuroki, Toshio RT "Molecular and cellular features of esophageal cancer cells."; RL J. Cancer Res. Clin. Oncol. 119:441-449(1993). // RX PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172; RA Sonoda, Itaru RA Imoto, Issei RA Inoue, Jun RA Shibata, Tatsuhiro RA Shimada, Yutaka RA Chin, Koei RA Imamura, Masayuki RA Amagasa, Teruo RA Gray, Joe W. RA Hirohashi, Setsuo RA Inazawa, Johji RT "Frequent silencing of low density lipoprotein receptor-related RT protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in RT esophageal squamous cell carcinoma."; RL Cancer Res. 64:3741-3747(2004). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652; RA Cowley, Glenn S. RA Weir, Barbara A. RA Vazquez, Francisca RA Tamayo, Pablo RA Scott, Justine A. RA Rusin, Scott RA East-Seletsky, Alexandra RA Ali, Levi D. RA Gerath, William F.J. RA Pantel, Sarah E. RA Lizotte, Patrick Hall RA Jiang, Guo-Zhi RA Hsiao, Jessica RA Tsherniak, Aviad RA Dwinell, Elizabeth RA Aoyama, Simon RA Okamoto, Michael RA Harrington, William RA Gelfand, Ellen T. RA Green, Thomas M. RA Tomko, Mark J. RA Gopal, Shuba RA Wong, Terence C. RA Li, Hu-Bo RA Howell, Sara RA Stransky, Nicolas RA Liefeld, Ted RA Jang, Dongkeun RA Bistline, Jonathan RA Meyers, Barbara Hill RA Armstrong, Scott Allen RA Anderson, Kenneth Carl RA Stegmaier, Kimberly RA Reich, Michael RA Pellman, David RA Boehm, Jesse S. RA Mesirov, Jill P. RA Golub, Todd Robert RA Root, David E. RA Hahn, William Chun RT "Parallel genome-scale loss of function screens in 216 cancer cell RT lines for the identification of context-specific genetic RT dependencies."; RL Sci. Data 1:140035.1-140035.12(2014). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. 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RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=9096669; DOI=10.1002/(SICI)1097-0215(19970328)71:1<79::AID-IJC14>3.0.CO;2-4; RA Barnas, Christoph RA Martel-Planche, Ghyslaine RA Furukawa, Yoichi RA Hollstein, Monica C. RA Montesano, Ruggero RA Hainaut, Pierre RT "Inactivation of the p53 protein in cell lines derived from human RT esophageal cancers."; RL Int. J. 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