ID SW837 AC CVCL_1729 SY SW-837; SW 837 DR CLO; CLO_0009200 DR CLO; CLO_0009224 DR EFO; EFO_0002372 DR CLDB; cl4447 DR CLDB; cl4448 DR CLDB; cl4972 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ATCC; CCL-235 DR BioGRID_ORCS_Cell_line; 453 DR BioSample; SAMN03472312 DR BioSample; SAMN10987996 DR cancercelllines; CVCL_1729 DR Cell_Model_Passport; SIDM00833 DR ChEMBL-Cells; CHEMBL3308361 DR ChEMBL-Targets; CHEMBL1075596 DR ColonAtlas; SW837 DR Cosmic; 724852 DR Cosmic; 873707 DR Cosmic; 909755 DR Cosmic; 948839 DR Cosmic; 983734 DR Cosmic; 985589 DR Cosmic; 986021 DR Cosmic; 995397 DR Cosmic; 1043830 DR Cosmic; 1122334 DR Cosmic; 1132696 DR Cosmic; 1184090 DR Cosmic; 1310943 DR Cosmic; 1312316 DR Cosmic; 1374627 DR Cosmic; 1479571 DR Cosmic; 1676728 DR Cosmic; 1708404 DR Cosmic; 1805269 DR Cosmic; 1995655 DR Cosmic; 2302020 DR Cosmic; 2664051 DR Cosmic; 2760072 DR Cosmic; 2800571 DR Cosmic-CLP; 909755 DR DepMap; ACH-000421 DR ECACC; 91031104 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 909755 DR GEO; GSM817 DR GEO; GSM206554 DR GEO; GSM383864 DR GEO; GSM513925 DR GEO; GSM514315 DR GEO; GSM741265 DR GEO; GSM827281 DR GEO; GSM887679 DR GEO; GSM888771 DR GEO; GSM1006239 DR GEO; GSM1006240 DR GEO; GSM1006241 DR GEO; GSM1346893 DR GEO; GSM1374937 DR GEO; GSM1448195 DR GEO; GSM1670513 DR GEO; GSM2550018 DR IARC_TP53; 95 DR IARC_TP53; 23571 DR ICLC; HTL99021 DR IGRhCellID; SW837 DR JCRB; JCRB9115 DR LiGeA; CCLE_838 DR LINCS_LDP; LCL-1292 DR Lonza; 1348 DR NCBI_Iran; C510 DR PharmacoDB; SW837_1546_2019 DR PRIDE; PXD005235 DR PRIDE; PXD005354 DR PRIDE; PXD005355 DR PRIDE; PXD030304 DR Progenetix; CVCL_1729 DR PubChem_Cell_line; CVCL_1729 DR SKY/M-FISH/CGH; 2849 DR Wikidata; Q54971210 RX PubMed=286328; RX PubMed=924690; RX PubMed=1000501; RX PubMed=6652615; RX PubMed=7104989; RX PubMed=7651727; RX PubMed=7824277; RX PubMed=8464898; RX PubMed=9715273; RX PubMed=10612807; RX PubMed=10737795; RX PubMed=11226274; RX PubMed=11687795; RX PubMed=12068308; RX PubMed=16418264; RX PubMed=18258742; RX PubMed=19927377; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=20570890; RX PubMed=20606684; RX PubMed=22460905; RX PubMed=23272949; RX PubMed=23932154; RX PubMed=24755471; RX PubMed=24840470; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25926053; RX PubMed=25944804; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=28683746; RX PubMed=28854368; RX PubMed=29101300; RX PubMed=29444439; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=31395879; RX PubMed=31978347; RX PubMed=35839778; WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Pawefish; -; https://www.cellosaurus.org/pawefish/ColonCellLineDescriptions/SW837.html CC Part of: AstraZeneca Colorectal cell line (AZCL) panel. CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: FGFR genetic alteration cell panel (ATCC TCP-1034). CC Part of: MD Anderson Cell Lines Project. CC Part of: NCI RAS program mutant KRAS cell line panel. CC Part of: TCGA-110-CL cell line panel. CC From: Scott and White Clinic; Temple; USA. CC Population: Caucasian. CC Doubling time: 169 hours (Note=At 5th passage) (PubMed=1000501); 40.60 hours (PubMed=25944804). CC HLA typing: A*32:01,32:01; B*35:01,35:01; C*04:01,04:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (PubMed=24755471; PubMed=25926053; PubMed=28683746; Sanger). CC Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Arg1450Ter (c.4348C>T); ClinVar=VCV000194585; Zygosity=Unspecified (PubMed=24755471). CC Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Leu403fs*34 (c.1208_1209insT); Zygosity=Unspecified (PubMed=24755471). CC Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (PubMed=12068308; PubMed=20570890; PubMed=24755471; PubMed=28683746). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Hemizygous (PubMed=7651727; PubMed=9715273; PubMed=16418264; PubMed=24755471; PubMed=28683746). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Glycomics; N-glycan profiling. CC Omics: Glycomics; O-glycan profiling. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; PTM; Phosphorylation; Quantitative. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; miRNA profiling; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Transcriptomics; Serial analysis of gene expression (SAGE). CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=2.4%; Native American=0%; East Asian, North=1.12%; East Asian, South=0.53%; South Asian=0%; European, North=65.15%; European, South=30.8% (PubMed=30894373). CC Derived from site: In situ; Rectum; UBERON=UBERON_0001052. ST Source(s): ATCC=CCL-235; Cosmic-CLP=909755; ECACC=91031104; PubMed=25877200; PubMed=25926053 ST Amelogenin: X ST CSF1PO: 10 ST D13S317: 13 ST D16S539: 12 ST D18S51: 17 ST D19S433: 13 ST D21S11: 28,31.2 ST D2S1338: 24 ST D3S1358: 18 ST D5S818: 12 ST D7S820: 9,12 ST D8S1179: 8,14 ST FGA: 25 ST Penta D: 9,11 ST Penta E: 11,12 ST TH01: 9.3 ST TPOX: 8,9 ST vWA: 15,16 DI NCIt; C9383; Rectal adenocarcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 53Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 45 // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=29101300; DOI=10.15252/msb.20177701; PMCID=PMC5731344; RA Frejno, Martin RA Zenezini Chiozzi, Riccardo RA Wilhelm, Mathias RA Koch, Heiner RA Zheng, Run-Sheng RA Klaeger, Susan RA Ruprecht, Benjamin RA Meng, Chen RA Kramer, Karl RA Jarzab, Anna RA Heinzlmeir, Stephanie RA Johnstone, Elaine RA Domingo, Enric RA Kerr, David James RA Jesinghaus, Moritz RA Slotta-Huspenina, Julia RA Weichert, Wilko RA Knapp, Stefan RA Feller, Stephan M. RA Kuster, Bernhard RT "Pharmacoproteomic characterisation of human colon and rectal RT cancer."; RL Mol. Syst. Biol. 13:951-951(2017). // RX PubMed=6652615; DOI=10.1016/0165-4608(83)90092-4; RA Chen, Tchaw-Ren RA Hay, Robert J. RA Macy, Marvin L. RT "Intercellular karyotypic similarity in near-diploid cell lines of RT human tumor origins."; RL Cancer Genet. Cytogenet. 10:351-362(1983). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=19927377; DOI=10.1002/gcc.20730; PMCID=PMC2818350; RA Knutsen, Turid RA Padilla-Nash, Hesed Maria RA Wangsa, Danny RA Barenboim-Stapleton, Linda RA Camps, Jordi RA McNeil, Nicole E. RA Difilippantonio, Michael J. RA Ried, Thomas RT "Definitive molecular cytogenetic characterization of 15 colorectal RT cancer cell lines."; RL Genes Chromosomes Cancer 49:204-223(2010). // RX PubMed=28683746; DOI=10.1186/s12943-017-0691-y; PMCID=PMC5498998; RA Berg, Kaja Christine Graue RA Eide, Peter W. RA Eilertsen, Ina A. RA Johannessen, Bjarne RA Bruun, Jarle RA Danielsen, Stine A. RA Bjornslett, Merete RA Meza-Zepeda, Leonardo Andres RA Eknaes, Mette RA Lind, Guro Elisabeth RA Myklebost, Ola RA Skotheim, Rolf Inge RA Sveen, Anita RA Lothe, Ragnhild Adelheid RT "Multi-omics of 34 colorectal cancer cell lines -- a resource for RT biomedical studies."; RL Mol. Cancer 16:116.1-116.16(2017). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028; RA Bracht, Karin RA Nicholls, Angela M. RA Liu, Ying RA Bodmer, Walter Fred RT "5-fluorouracil response in a large panel of colorectal cancer cell RT lines is associated with mismatch repair deficiency."; RL Br. J. Cancer 103:340-346(2010). // RX PubMed=1000501; RA Leibovitz, Albert RA Stinson, James C. RA McCombs, William B. 3rd RA McCoy, Cameron E. RA Mazur, Kenneth C. RA Mabry, Nancy D. RT "Classification of human colorectal adenocarcinoma cell lines."; RL Cancer Res. 36:4562-4569(1976). // RX PubMed=25944804; DOI=10.1158/1078-0432.CCR-14-2457; RA Bazzocco, Sarah RA Dopeso, Higinio RA Carton-Garcia, Fernando RA Macaya, Irati RA Andretta, Elena RA Chionh, Fiona RA Rodrigues, Paulo RA Garrido, Miriam RA Alazzouzi, Hafid RA Nieto, Rocio RA Sanchez, Alex RA Schwartz, Simo Jr. RA Bilic, Josipa RA Mariadason, John M. RA Arango, Diego RT "Highly expressed genes in rapidly proliferating tumor cells as new RT targets for colorectal cancer treatment."; RL Clin. Cancer Res. 21:3695-3704(2015). // RX PubMed=31395879; DOI=10.1038/s41467-019-11415-2; PMCID=PMC6687785; RA Yu, Katharine RA Chen, Bin RA Aran, Dvir RA Charalel, Joe RA Yau, Christina RA Wolf, Douglas M. RA van 't Veer, Laura J. RA Butte, Atul Janardhan RA Goldstein, Ted RA Sirota, Marina RT "Comprehensive transcriptomic analysis of cell lines as models of RT primary tumors across 22 tumor types."; RL Nat. Commun. 10:3574.1-3574.11(2019). // RX PubMed=23932154; DOI=10.1016/j.radonc.2013.06.032; RA Salendo, Junius RA Spitzner, Melanie RA Kramer, Frank RA Zhang, Xin RA Jo, Peter RA Wolff, Hendrik A. RA Kitz, Julia RA Kaulfuss, Silke RA Beissbarth, Tim RA Dobbelstein, Matthias RA Ghadimi, Michael RA Grade, Marian RA Gaedcke, Jochen RT "Identification of a microRNA expression signature for RT chemoradiosensitivity of colorectal cancer cells, involving RT miRNAs-320a, -224, -132 and let7g."; RL Radiother. Oncol. 108:451-457(2013). // RX PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192; PMCID=PMC2943514; RA Janakiraman, Manickam RA Vakiani, Efsevia RA Zeng, Zhao-Shi RA Pratilas, Christine A. RA Taylor, Barry Stephen RA Chitale, Dhananjay RA Halilovic, Ensar RA Wilson, Manda RA Huberman, Kety RA Ricarte Filho, Julio Cezar Marques RA Persaud, Yogindra RA Levine, Douglas A. RA Fagin, James Alexander RA Jhanwar, Suresh C. RA Mariadason, John M. RA Lash, Alex RA Ladanyi, Marc RA Saltz, Leonard B. RA Heguy, Adriana RA Paty, Philip B. RA Solit, David B. RT "Genomic and biological characterization of exon 4 KRAS mutations in RT human cancer."; RL Cancer Res. 70:5901-5911(2010). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin K. RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013; RA Mouradov, Dmitri RA Sloggett, Clare RA Jorissen, Robert N. RA Love, Christopher G. RA Li, Shan RA Burgess, Antony Wilks RA Arango, Diego RA Strausberg, Robert L. RA Buchanan, Daniel RA Wormald, Samuel RA O'Connor, Liam RA Wilding, Jennifer L. RA Bicknell, David C. RA Tomlinson, Ian Philip Mark RA Bodmer, Walter Fred RA Mariadason, John M. RA Sieber, Oliver M. RT "Colorectal cancer cell lines are representative models of the main RT molecular subtypes of primary cancer."; RL Cancer Res. 74:3238-3247(2014). // RX PubMed=28854368; DOI=10.1016/j.celrep.2017.08.010; PMCID=PMC5583477; RA Roumeliotis, Theodoros I. RA Williams, Steven P. RA Goncalves, Emanuel RA Alsinet, Clara RA Del Castillo Velasco-Herrera, Martin RA Aben, Nanne RA Ghavidel, Fatemeh Zamanzad RA Michaut, Magali RA Schubert, Michael RA Price, Stacey RA Wright, James C. RA Yu, Lu RA Yang, Mi RA Dienstmann, Rodrigo RA Guinney, Justin H. RA Beltrao, Pedro RA Brazma, Alvis RA Pardo, Mercedes RA Stegle, Oliver RA Adams, David J. RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Choudhary, Jyoti S. RT "Genomic determinants of protein abundance variation in colorectal RT cancer cells."; RL Cell Rep. 20:2201-2214(2017). // RX PubMed=25926053; DOI=10.1038/ncomms8002; RA Medico, Enzo RA Russo, Mariangela RA Picco, Gabriele RA Cancelliere, Carlotta RA Valtorta, Emanuele RA Corti, Giorgio RA Buscarino, Michela RA Isella, Claudio RA Lamba, Simona RA Martinoglio, Barbara RA Veronese, Silvio RA Siena, Salvatore RA Sartore-Bianchi, Andrea RA Beccuti, Marco RA Mottolese, Marcella RA Linnebacher, Michael RA Cordero, Francesca RA Di Nicolantonio, Federica RA Bardelli, Alberto RT "The molecular landscape of colorectal cancer cell lines unveils RT clinically actionable kinase targets."; RL Nat. Commun. 6:7002.1-7002.10(2015). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=10737795; DOI=10.1073/pnas.97.7.3352; PMCID=PMC16243; RA Rowan, Andrew J. RA Lamlum, Hanan RA Ilyas, Mohammad RA Wheeler, James M.D. RA Straub, Jannes RA Papadopoulou, Angeliki RA Bicknell, David C. RA Bodmer, Walter Fred RA Tomlinson, Ian Philip Mark RT "APC mutations in sporadic colorectal tumors: a mutational 'hotspot' RT and interdependence of the 'two hits'."; RL Proc. Natl. Acad. Sci. U.S.A. 97:3352-3357(2000). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura E. RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=9715273; DOI=10.1038/sj.onc.1201986; RA Eshleman, James Richard RA Casey, Graham RA Kochera, Mary E. RA Sedwick, Wallace David RA Swinler, Sandra E. RA Veigl, Martina L. RA Willson, James K.V. RA Schwartz, Stuart RA Markowitz, Sanford David RT "Chromosome number and structure both are markedly stable in RER RT colorectal cancers and are not destabilized by mutation of p53."; RL Oncogene 17:719-725(1998). // RX PubMed=7104989; DOI=10.1016/0165-4608(82)90076-0; RA Chen, Tchaw-Ren RA Hay, Robert J. RA Macy, Marvin L. RT "Karyotype consistency in human colorectal carcinoma cell lines RT established in vitro."; RL Cancer Genet. Cytogenet. 6:93-117(1982). // RX PubMed=18258742; DOI=10.1073/pnas.0712176105; PMCID=PMC2268141; RA Emaduddin, Muhammad RA Bicknell, David C. RA Bodmer, Walter Fred RA Feller, Stephan M. RT "Cell growth, global phosphotyrosine elevation, and c-Met RT phosphorylation through Src family kinases in colorectal cancer RT cells."; RL Proc. Natl. Acad. Sci. U.S.A. 105:2358-2362(2008). // RX PubMed=924690; DOI=10.1002/ijc.2910200505; RA Kerbel, Robert S. RA Pross, Hugh F. RA Leibovitz, Albert RT "Analysis of established human carcinoma cell lines for RT lymphoreticular-associated membrane receptors."; RL Int. J. Cancer 20:673-679(1977). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, A. Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=24840470; DOI=10.1016/j.jprot.2014.05.002; RA Chik, Jenny H.L. RA Zhou, Jerry RA Moh, Edward S.X. RA Christopherson, Richard RA Clarke, Stephen J. RA Molloy, Mark P. RA Packer, Nicolle H. RT "Comprehensive glycomics comparison between colon cancer cell cultures RT and tumours: implications for biomarker studies."; RL J. Proteomics 108:146-162(2014). // RX PubMed=7651727; RA Kastrinakis, William Vasilios RA Ramchurren, Nirasha RA Rieger, Karen M. RA Hess, Donald T. RA Loda, Massimo RA Steele, Glenn RA Summerhayes, Ian C. RT "Increased incidence of p53 mutations is associated with hepatic RT metastasis in colorectal neoplastic progression."; RL Oncogene 11:647-652(1995). // RX PubMed=23272949; DOI=10.1186/1755-8794-5-66; PMCID=PMC3543849; RA Schlicker, Andreas RA Beran, Garry RA Chresta, Christine M. RA McWalter, Gael RA Pritchard, Alison RA Weston, Susie RA Runswick, Sarah RA Davenport, Sara RA Heathcote, Kerry RA Castro, Denis Alferez RA Orphanides, George RA French, Tim RA Wessels, Lodewyk F.A. RT "Subtypes of primary colorectal tumors correlate with response to RT targeted treatment in colorectal cell lines."; RL BMC Med. Genomics 5:66.1-66.15(2012). // RX PubMed=286328; DOI=10.1073/pnas.76.3.1438; PMCID=PMC383267; RA Herlyn, Meenhard RA Steplewski, Zenon RA Herlyn, Dorothee RA Koprowski, Hilary RT "Colorectal carcinoma-specific antigen: detection by means of RT monoclonal antibodies."; RL Proc. Natl. Acad. Sci. U.S.A. 76:1438-1442(1979). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=16418264; DOI=10.1073/pnas.0510146103; PMCID=PMC1327731; RA Liu, Ying RA Bodmer, Walter Fred RT "Analysis of p53 mutations and their expression in 56 colorectal RT cancer cell lines."; RL Proc. Natl. Acad. Sci. U.S.A. 103:976-981(2006). // RX PubMed=11226274; DOI=10.1073/pnas.041603298; PMCID=PMC30173; RA Abdel-Rahman, Wael M. RA Katsura, Kanade RA Rens, Willem RA Gorman, Patricia A. RA Sheer, Denise RA Bicknell, David C. RA Bodmer, Walter Fred RA Arends, Mark J. RA Wyllie, Andrew Hamilton RA Edwards, Paul A.W. RT "Spectral karyotyping suggests additional subsets of colorectal RT cancers characterized by pattern of chromosome rearrangement."; RL Proc. Natl. Acad. Sci. U.S.A. 98:2538-2543(2001). // RX PubMed=12068308; DOI=10.1038/nature00766; RA Davies, Helen R. RA Bignell, Graham Robert RA Cox, Charles RA Stephens, Philip J. RA Edkins, Sarah RA Clegg, Sheila RA Teague, Jon W. RA Woffendin, Hayley RA Garnett, Mathew J. RA Bottomley, William RA Davis, Neil RA Dicks, Ed RA Ewing, Rebecca RA Floyd, Yvonne RA Gray, Kristian RA Hall, Sarah RA Hawes, Rachel RA Hughes, Jaime RA Kosmidou, Vivian RA Menzies, Andrew RA Mould, Catherine RA Parker, Adrian RA Stevens, Claire RA Watt, Stephen RA Hooper, Steven RA Wilson, Rebecca RA Jayatilake, Hiran RA Gusterson, Barry Austin RA Cooper, Colin S. RA Shipley, Janet M. RA Hargrave, Darren RA Pritchard-Jones, Kathy RA Maitland, Norman J. RA Chenevix-Trench, Georgia RA Riggins, Gregory J. RA Bigner, Darell Doty RA Palmieri, Giuseppe RA Cossu, Antonio RA Flanagan, Adrienne M. RA Nicholson, Andrew RA Ho, Judy W.C. RA Leung, Suet Yi RA Yuen, Siu Tsan RA Weber, Barbara L. RA Seigler, Hilliard Foster RA Darrow, Timothy L. RA Paterson, Hugh F. RA Marais, Richard RA Marshall, Christopher John RA Wooster, Richard RA Stratton, Michael Rudolf RA Futreal, P. Andrew RT "Mutations of the BRAF gene in human cancer."; RL Nature 417:949-954(2002). // RX PubMed=8464898; DOI=10.1073/pnas.90.7.2842; PMCID=PMC46192; RA Browning, Michael J. RA Krausa, Peter RA Rowan, Andrew J. RA Bicknell, David C. RA Bodmer, Julia Gwynaeth RA Bodmer, Walter Fred RT "Tissue typing the HLA-A locus from genomic DNA by sequence-specific RT PCR: comparison of HLA genotype and surface expression on colorectal RT tumor cell lines."; RL Proc. Natl. Acad. Sci. U.S.A. 90:2842-2845(1993). // RX PubMed=11687795; DOI=10.1038/ng754; RA Snijders, Antoine M. RA Nowak, Norma Jean RA Segraves, Richard RA Blackwood, Stephanie RA Brown, Nils RA Conroy, Jeffrey RA Hamilton, Greg RA Hindle, Anna Katherine RA Huey, Bing RA Kimura, Karen RA Law, Sindy RA Myambo, Ken RA Palmer, Joel RA Ylstra, Bauke RA Yue, Jingzhu Pearl RA Gray, Joe W. RA Jain, Ajay N. RA Pinkel, Daniel RA Albertson, Donna G. RT "Assembly of microarrays for genome-wide measurement of DNA copy RT number."; RL Nat. Genet. 29:263-264(2001). // RX PubMed=7824277; RA Eshleman, James Richard RA Lang, Evan Z. RA Bowerfind, Gordana K. RA Parsons, Ramon RA Vogelstein, Bert RA Willson, James K.V. RA Veigl, Martina L. RA Sedwick, Wallace David RA Markowitz, Sanford David RT "Increased mutation rate at the hprt locus accompanies microsatellite RT instability in colon cancer."; RL Oncogene 10:33-37(1995). // RX PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826; RA Yuan, Tina L. RA Amzallag, Arnaud RA Bagni, Rachel RA Yi, Ming RA Afghani, Shervin RA Burgan, William RA Fer, Nicole RA Strathern, Leslie A. RA Powell, Katie RA Smith, Brian RA Waters, Andrew Michael RA Drubin, David Alan RA Thomson, Ty RA Liao, Rosy RA Greninger, Patricia RA Stein, Giovanna T. RA Murchie, Ellen RA Cortez, Eliane RA Egan, Regina K. RA Procter, Lauren RA Bess, Matthew RA Cheng, Kwong Tai RA Lee, Chih-Shia RA Lee, Liam Changwoo RA Fellmann, Christof RA Stephens, Robert RA Luo, Ji RA Lowe, Scott William RA Benes, Cyril Henri RA McCormick, Frank RT "Differential effector engagement by oncogenic KRAS."; RL Cell Rep. 22:1889-1902(2018). // RX PubMed=10612807; DOI=10.1002/(SICI)1098-2264(200002)27:2<183::AID-GCC10>3.0.CO;2-P; PMCID=PMC4721570; RA Ghadimi, B. Michael RA Sackett, Dan L. RA Difilippantonio, Michael J. RA Schrock, Evelin RA Neumann, Thomas RA Jauho, Annukka RA Auer, Gert RA Ried, Thomas RT "Centrosome amplification and instability occurs exclusively in RT aneuploid, but not in diploid colorectal cancer cell lines, and RT correlates with numerical chromosomal aberrations."; RL Genes Chromosomes Cancer 27:183-190(2000). //