ID SW780 AC CVCL_1728 SY SW-780; SW 780 DR BTO; BTO_0006307 DR CLO; CLO_0009199 DR EFO; EFO_0002371 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ATCC; CRL-2169 DR BioSample; SAMN03473242 DR BioSample; SAMN10988174 DR cancercelllines; CVCL_1728 DR CCRID; 3101HUMTCHu219 DR Cell_Model_Passport; SIDM01160 DR ChEMBL-Cells; CHEMBL3308468 DR ChEMBL-Targets; CHEMBL1075595 DR CLS; 305098 DR Cosmic; 687457 DR Cosmic; 1285128 DR Cosmic; 1285990 DR Cosmic; 1819323 DR Cosmic; 2037958 DR Cosmic; 2050464 DR Cosmic; 2057457 DR Cosmic; 2444257 DR Cosmic; 2686117 DR Cosmic; 2700998 DR Cosmic-CLP; 687457 DR DepMap; ACH-000384 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 687457 DR GEO; GSM136235 DR GEO; GSM827294 DR GEO; GSM887678 DR GEO; GSM888770 DR GEO; GSM1374936 DR GEO; GSM1574556 DR GEO; GSM1670512 DR GEO; GSM2143918 DR GEO; GSM2143919 DR GEO; GSM2143920 DR IARC_TP53; 27584 DR IGRhCellID; SW780 DR LiGeA; CCLE_886 DR LINCS_LDP; LCL-1718 DR PharmacoDB; SW780_1545_2019 DR PRIDE; PXD030304 DR Progenetix; CVCL_1728 DR PubChem_Cell_line; CVCL_1728 DR Ubigene; YC-C138 DR Wikidata; Q54971204 RX PubMed=571047; RX PubMed=833871; RX PubMed=924690; RX PubMed=3518877; RX PubMed=6244232; RX PubMed=6744315; RX PubMed=7459858; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=22460905; RX PubMed=24018021; RX PubMed=24035680; RX PubMed=24367658; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25997541; RX PubMed=26589293; RX PubMed=27189164; RX PubMed=27270441; RX PubMed=27397505; RX PubMed=29732388; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31395879; RX PubMed=35839778; WW Info; Synapse; Bladder Cancer exome; https://www.synapse.org/Synapse:syn4970200 WW Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/other-bladder-cervical/sw780-xenograft-model/ CC Part of: BLA-40 bladder carcinoma cell line panel. CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: TCGA-110-CL cell line panel. CC Part of: UBC-40 urothelial bladder cancer cell line index. CC From: Scott and White Clinic; Temple; USA. CC Population: Caucasian. CC HLA typing: A*03:01,23:01; B*07:02,41:02; C*07:02,17:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=24035680). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.52%; Native American=0.16%; East Asian, North=0.43%; East Asian, South=0.73%; South Asian=3.11%; European, North=68.95%; European, South=26.09% (PubMed=30894373). CC Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. ST Source(s): ATCC=CRL-2169; Cosmic-CLP=687457; PubMed=25877200; PubMed=27270441 ST Amelogenin: X ST CSF1PO: 10,11 ST D13S317: 11,12 ST D16S539: 9,11 ST D18S51: 15 ST D19S433: 13,15 ST D21S11: 29,30 ST D2S1338: 19,22 ST D3S1358: 16,18 ST D5S818: 11,12 ST D7S820: 9,10 ST D8S1179: 13 ST FGA: 19,20 ST Penta D: 9 ST Penta E: 12 ST TH01: 6 ST TPOX: 8 ST vWA: 16 (PubMed=27270441) ST vWA: 16,19 (ATCC=CRL-2169; Cosmic-CLP=687457; PubMed=25877200) DI NCIt; C4912; Bladder carcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 80Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 44 CH CVCL_C3GV ! SW780 FOXP3 CH CVCL_C3GW ! SW780 FOXP3Delta3 CH CVCL_E1CI ! Ubigene SW780 NECTIN4 KO // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=24367658; DOI=10.1371/journal.pone.0084411; PMCID=PMC3867501; RA Ross, Rebecca L. RA Burns, Julie E. RA Taylor, Claire F. RA Mellor, Paul RA Anderson, Deborah H. RA Knowles, Margaret A. RT "Identification of mutations in distinct regions of p85 alpha in RT urothelial cancer."; RL PLoS ONE 8:e84411.1-e84411.11(2013). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=27270441; DOI=10.1038/onc.2016.172; PMCID=PMC5140783; RA Nickerson, Michael L. RA Witte, Nicolle RA McGee Im, Kate RA Turan, Sevilay RA Owens, Charles R. RA Misner, Kevin RA Tsang, Shirley X. RA Cai, Zhi-Ming RA Wu, Sen RA Dean, Michael RA Costello, James C. RA Theodorescu, Dan RT "Molecular analysis of urothelial cancer cell lines for modeling tumor RT biology and drug response."; RL Oncogene 36:35-46(2017). // RX PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036; RA Earl, Julie RA Rico, Daniel RA Carrillo-de-Santa-Pau, Enrique RA Rodriguez-Santiago, Benjamin RA Mendez-Pertuz, Marinela RA Auer, Herbert RA Gomez, Gonzalo RA Grossman, Herbert Barton RA Pisano, David G. RA Schulz, Wolfgang A. RA Perez-Jurado, Luis A. RA Carrato, Alfredo RA Theodorescu, Dan RA Chanock, Stephen Jacob RA Valencia, Alfonso RA Real, Francisco X. RT "The UBC-40 Urothelial Bladder Cancer cell line index: a genomic RT resource for functional studies."; RL BMC Genomics 16:403.1-403.16(2015). // RX PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350; RA Zuiverloon, Tahlita C.M. RA de Jong, Florus C. RA Costello, James C. RA Theodorescu, Dan RT "Systematic review: characteristics and preclinical uses of bladder RT cancer cell lines."; RL Bladder Cancer 4:169-183(2018). // RX PubMed=7459858; RA Rousset, Monique RA Zweibaum, Alain RA Fogh, Jorgen RT "Presence of glycogen and growth-related variations in 58 cultured RT human tumor cell lines of various tissue origins."; RL Cancer Res. 41:1165-1170(1981). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=6744315; RA Kyriazis, Aikaterini A. RA Kyriazis, Andreas P. RA McCombs, William B. 3rd RA Peterson, Ward Davis Jr. RT "Morphological, biological, and biochemical characteristics of human RT bladder transitional cell carcinomas grown in tissue culture and in RT nude mice."; RL Cancer Res. 44:3997-4005(1984). // RX PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052; RA Allory, Yves RA Beukers, Willemien RA Sagrera, Ana RA Flandez, Marta RA Marques, Miriam RA Marquez, Mirari RA van der Keur, Kirstin A. RA Dyrskjot, Lars RA Lurkin, Irene RA Vermeij, Marcel RA Carrato, Alfredo RA Lloreta, Josep RA Lorente, Jose A. RA Carrillo-de-Santa-Pau, Enrique RA Masius, Roy G. RA Kogevinas, Manolis RA Steyerberg, Ewout Willem RA van Tilborg, Angela A.G. RA Abas, Cheno RA Orntoft, Torben Falck RA Zuiverloon, Tahlita C.M. RA Malats, Nuria RA Zwarthoff, Ellen C. RA Real, Francisco X. RT "Telomerase reverse transcriptase promoter mutations in bladder RT cancer: high frequency across stages, detection in urine, and lack of RT association with outcome."; RL Eur. Urol. 65:360-366(2014). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=31395879; DOI=10.1038/s41467-019-11415-2; PMCID=PMC6687785; RA Yu, Katharine RA Chen, Bin RA Aran, Dvir RA Charalel, Joe RA Yau, Christina RA Wolf, Douglas M. RA van 't Veer, Laura J. RA Butte, Atul Janardhan RA Goldstein, Ted RA Sirota, Marina RT "Comprehensive transcriptomic analysis of cell lines as models of RT primary tumors across 22 tumor types."; RL Nat. Commun. 10:3574.1-3574.11(2019). // RX PubMed=6244232; RA Williams, Richard D. RT "Human urologic cancer cell lines."; RL Invest. Urol. 17:359-363(1980). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=571047; RA Fogh, Jorgen RT "Cultivation, characterization, and identification of human tumor RT cells with emphasis on kidney, testis, and bladder tumors."; RL Natl. Cancer Inst. Monogr. 49:5-9(1978). // RX PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057; RA Hurst, Carolyn D. RA Platt, Fiona M. RA Knowles, Margaret A. RT "Comprehensive mutation analysis of the TERT promoter in bladder RT cancer and detection of mutations in voided urine."; RL Eur. Urol. 65:367-369(2014). // RX PubMed=3518877; DOI=10.3109/07357908609038260; RA Fogh, Jorgen RT "Human tumor lines for cancer research."; RL Cancer Invest. 4:157-184(1986). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura E. RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=27189164; DOI=10.1158/1078-0432.CCR-15-2581; RA Zhang, Han-Wei RA Prado, Kris RA Zhang, Kelvin X. RA Peek, Elizabeth M. RA Lee, Jane RA Wang, Xiao-Yan RA Huang, Jiao-Ti RA Li, Gang RA Pellegrini, Matteo RA Chin, Arnold I. RT "Biased expression of the FOXP3Delta3 isoform in aggressive bladder RT cancer mediates differentiation and cisplatin chemotherapy RT resistance."; RL Clin. Cancer Res. 22:5349-5361(2016). // RX PubMed=924690; DOI=10.1002/ijc.2910200505; RA Kerbel, Robert S. RA Pross, Hugh F. RA Leibovitz, Albert RT "Analysis of established human carcinoma cell lines for RT lymphoreticular-associated membrane receptors."; RL Int. J. Cancer 20:673-679(1977). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=833871; DOI=10.1093/jnci/58.2.209; RA Fogh, Jorgen RA Wright, William C. RA Loveless, James D. RT "Absence of HeLa cell contamination in 169 cell lines derived from RT human tumors."; RL J. Natl. Cancer Inst. 58:209-214(1977). //