ID   SW780
AC   CVCL_1728
SY   SW-780; SW 780
DR   BTO; BTO_0006307
DR   CLO; CLO_0009199
DR   EFO; EFO_0002371
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-2169
DR   BioSample; SAMN03473242
DR   BioSample; SAMN10988174
DR   cancercelllines; CVCL_1728
DR   CCRID; 3101HUMTCHu219
DR   Cell_Model_Passport; SIDM01160
DR   ChEMBL-Cells; CHEMBL3308468
DR   ChEMBL-Targets; CHEMBL1075595
DR   CLS; 305098
DR   Cosmic; 687457
DR   Cosmic; 1285128
DR   Cosmic; 1285990
DR   Cosmic; 1819323
DR   Cosmic; 2037958
DR   Cosmic; 2050464
DR   Cosmic; 2057457
DR   Cosmic; 2444257
DR   Cosmic; 2686117
DR   Cosmic; 2700998
DR   Cosmic-CLP; 687457
DR   DepMap; ACH-000384
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   GDSC; 687457
DR   GEO; GSM136235
DR   GEO; GSM827294
DR   GEO; GSM887678
DR   GEO; GSM888770
DR   GEO; GSM1374936
DR   GEO; GSM1574556
DR   GEO; GSM1670512
DR   GEO; GSM2143918
DR   GEO; GSM2143919
DR   GEO; GSM2143920
DR   IARC_TP53; 27584
DR   IGRhCellID; SW780
DR   LiGeA; CCLE_886
DR   LINCS_LDP; LCL-1718
DR   PharmacoDB; SW780_1545_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1728
DR   PubChem_Cell_line; CVCL_1728
DR   Ubigene; YC-C138
DR   Wikidata; Q54971204
RX   PubMed=571047;
RX   PubMed=833871;
RX   PubMed=924690;
RX   PubMed=3518877;
RX   PubMed=6244232;
RX   PubMed=6744315;
RX   PubMed=7459858;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=22460905;
RX   PubMed=24018021;
RX   PubMed=24035680;
RX   PubMed=24367658;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25997541;
RX   PubMed=26589293;
RX   PubMed=27189164;
RX   PubMed=27270441;
RX   PubMed=27397505;
RX   PubMed=29732388;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31395879;
RX   PubMed=35839778;
WW   Info; Synapse; Bladder Cancer exome; https://www.synapse.org/Synapse:syn4970200
WW   Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/other-bladder-cervical/sw780-xenograft-model/
CC   Part of: BLA-40 bladder carcinoma cell line panel.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: TCGA-110-CL cell line panel.
CC   Part of: UBC-40 urothelial bladder cancer cell line index.
CC   From: Scott and White Clinic; Temple; USA.
CC   Population: Caucasian.
CC   HLA typing: A*03:01,23:01; B*07:02,41:02; C*07:02,17:01 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=24035680).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0.52%; Native American=0.16%; East Asian, North=0.43%; East Asian, South=0.73%; South Asian=3.11%; European, North=68.95%; European, South=26.09% (PubMed=30894373).
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
ST   Source(s): ATCC=CRL-2169; Cosmic-CLP=687457; PubMed=25877200; PubMed=27270441
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11,12
ST   D16S539: 9,11
ST   D18S51: 15
ST   D19S433: 13,15
ST   D21S11: 29,30
ST   D2S1338: 19,22
ST   D3S1358: 16,18
ST   D5S818: 11,12
ST   D7S820: 9,10
ST   D8S1179: 13
ST   FGA: 19,20
ST   Penta D: 9
ST   Penta E: 12
ST   TH01: 6
ST   TPOX: 8
ST   vWA: 16 (PubMed=27270441)
ST   vWA: 16,19 (ATCC=CRL-2169; Cosmic-CLP=687457; PubMed=25877200)
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   80Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 44
//
RX   PubMed=571047;
RA   Fogh, Jorgen
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RT   cells with emphasis on kidney, testis, and bladder tumors.";
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//
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RA   Fogh, Jorgen
RA   Wright, William C.
RA   Loveless, James D.
RT   "Absence of HeLa cell contamination in 169 cell lines derived from
RT   human tumors.";
RL   J. Natl. Cancer Inst. 58:209-214(1977).
//
RX   PubMed=924690; DOI=10.1002/ijc.2910200505;
RA   Kerbel, Robert S.
RA   Pross, Hugh F.
RA   Leibovitz, Albert
RT   "Analysis of established human carcinoma cell lines for
RT   lymphoreticular-associated membrane receptors.";
RL   Int. J. Cancer 20:673-679(1977).
//
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RA   Fogh, Jorgen
RT   "Human tumor lines for cancer research.";
RL   Cancer Invest. 4:157-184(1986).
//
RX   PubMed=6244232;
RA   Williams, Richard D.
RT   "Human urologic cancer cell lines.";
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//
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RA   Kyriazis, Andreas P.
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RT   bladder transitional cell carcinomas grown in tissue culture and in
RT   nude mice.";
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//
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RA   Fogh, Jorgen
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RT   human tumor cell lines of various tissue origins.";
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//
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RA   Greninger, Patricia
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//
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RA   Venkatesan, Kavitha
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RA   Sonkin, Dmitriy
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RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
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RA   Mapa, Felipa A.
RA   Thibault, Joseph
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RA   Porter, Jeff
RA   Warmuth, Markus
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RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
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RA   Allory, Yves
RA   Beukers, Willemien
RA   Sagrera, Ana
RA   Flandez, Marta
RA   Marques, Miriam
RA   Marquez, Mirari
RA   van der Keur, Kirstin A.
RA   Dyrskjot, Lars
RA   Lurkin, Irene
RA   Vermeij, Marcel
RA   Carrato, Alfredo
RA   Lloreta, Josep
RA   Lorente, Jose A.
RA   Carrillo-de-Santa-Pau, Enrique
RA   Masius, Roy G.
RA   Kogevinas, Manolis
RA   Steyerberg, Ewout Willem
RA   van Tilborg, Angela A.G.
RA   Abas, Cheno
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RA   Real, Francisco X.
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RT   cancer: high frequency across stages, detection in urine, and lack of
RT   association with outcome.";
RL   Eur. Urol. 65:360-366(2014).
//
RX   PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057;
RA   Hurst, Carolyn D.
RA   Platt, Fiona M.
RA   Knowles, Margaret A.
RT   "Comprehensive mutation analysis of the TERT promoter in bladder
RT   cancer and detection of mutations in voided urine.";
RL   Eur. Urol. 65:367-369(2014).
//
RX   PubMed=24367658; DOI=10.1371/journal.pone.0084411; PMCID=PMC3867501;
RA   Ross, Rebecca L.
RA   Burns, Julie E.
RA   Taylor, Claire F.
RA   Mellor, Paul
RA   Anderson, Deborah H.
RA   Knowles, Margaret A.
RT   "Identification of mutations in distinct regions of p85 alpha in
RT   urothelial cancer.";
RL   PLoS ONE 8:e84411.1-e84411.11(2013).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
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RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
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RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
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RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036;
RA   Earl, Julie
RA   Rico, Daniel
RA   Carrillo-de-Santa-Pau, Enrique
RA   Rodriguez-Santiago, Benjamin
RA   Mendez-Pertuz, Marinela
RA   Auer, Herbert
RA   Gomez, Gonzalo
RA   Grossman, Herbert Barton
RA   Pisano, David G.
RA   Schulz, Wolfgang A.
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RA   Chanock, Stephen Jacob
RA   Valencia, Alfonso
RA   Real, Francisco X.
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RT   resource for functional studies.";
RL   BMC Genomics 16:403.1-403.16(2015).
//
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RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
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//
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RT   cancer mediates differentiation and cisplatin chemotherapy
RT   resistance.";
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//
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RA   Turan, Sevilay
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RT   biology and drug response.";
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//
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RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
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//
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//
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//
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RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
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RT   Encyclopedia.";
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//
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RA   Yu, Katharine
RA   Chen, Bin
RA   Aran, Dvir
RA   Charalel, Joe
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RA   van 't Veer, Laura J.
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RT   primary tumors across 22 tumor types.";
RL   Nat. Commun. 10:3574.1-3574.11(2019).
//
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RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
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RA   Lucas, Natasha
RA   Beck, Alexandra
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RA   Hecker, Michael
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RA   Mali, Iman
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RA   Richardson, Laura
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RA   Shepherd, Rebecca
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RA   Wu, Yang-Xiu
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RA   Robinson, Phillip James
RA   Zhong, Qing
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RA   Reddel, Roger Robert
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RL   Cancer Cell 40:835-849.e8(2022).
//