ID   RCM-1 [Human rectal adenocarcinoma]
AC   CVCL_1648
SY   RCM1
DR   CLO; CLO_0009972
DR   EFO; EFO_0006476
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   BioGRID_ORCS_Cell_line; 996
DR   BioSample; SAMN03472886
DR   BioSample; SAMN10988165
DR   cancercelllines; CVCL_1648
DR   Cell_Model_Passport; SIDM00359
DR   ChEMBL-Cells; CHEMBL3308125
DR   ChEMBL-Targets; CHEMBL1075562
DR   ColonAtlas; RCM1
DR   Cosmic; 873704
DR   Cosmic; 909263
DR   Cosmic; 1122329
DR   Cosmic; 1184088
DR   Cosmic; 1187314
DR   Cosmic; 1995616
DR   Cosmic-CLP; 909263
DR   DepMap; ACH-000565
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   EGA; EGAS00001002554
DR   GDSC; 909263
DR   GEO; GSM827229
DR   GEO; GSM887526
DR   GEO; GSM888608
DR   GEO; GSM1374846
DR   GEO; GSM1448098
DR   GEO; GSM1670367
DR   IARC_TP53; 21282
DR   JCRB; JCRB0256
DR   LiGeA; CCLE_779
DR   LINCS_LDP; LCL-1290
DR   PharmacoDB; RCM1_1295_2019
DR   PRIDE; PXD005235
DR   PRIDE; PXD005354
DR   PRIDE; PXD005355
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1648
DR   PubChem_Cell_line; CVCL_1648
DR   Wikidata; Q54949516
RX   PubMed=2570482;
RX   PubMed=3198327;
RX   PubMed=8348978;
RX   PubMed=9247707;
RX   PubMed=9290701;
RX   PubMed=16418264;
RX   PubMed=18258742;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=20606684;
RX   PubMed=22460905;
RX   PubMed=23272949;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25926053;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28854368;
RX   PubMed=29101300;
RX   PubMed=29444439;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=35839778;
CC   Part of: AstraZeneca Colorectal cell line (AZCL) panel.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: NCI RAS program mutant KRAS cell line panel.
CC   Population: Japanese.
CC   Doubling time: 71.4 hours (PubMed=2570482).
CC   HLA typing: A*24:02,24:02; B*51:01,54:01; C*01:02,14:02; DQA1*01:02,05:02; DQB1*05:01,05:01; DRB1*01:01,12:01 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (PubMed=25926053; Sanger).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Arg216Ter (c.646C>T); ClinVar=VCV000127312; Zygosity=Heterozygous (Cosmic-CLP; DepMap).
CC   Sequence variation: Mutation; HGNC; 3373; EP300; Simple; p.Gln1740Ter (c.5218C>T); Zygosity=Heterozygous (Cosmic-CLP; DepMap).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (Cosmic-CLP; DepMap).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Homozygous (PubMed=16418264; Cosmic-CLP; DepMap).
CC   Omics: CRISPR phenotypic screen.
CC   Omics: Deep exome analysis.
CC   Omics: Deep proteome analysis.
CC   Omics: Deep quantitative phosphoproteome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Genome ancestry: African=0.97%; Native American=0%; East Asian, North=75.44%; East Asian, South=22.81%; South Asian=0.01%; European, North=0%; European, South=0.77% (PubMed=30894373).
CC   Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
ST   Source(s): Cosmic-CLP; JCRB; PubMed=25877200; PubMed=25926053
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 10,12
ST   D16S539: 9,11,12 (Cosmic-CLP)
ST   D16S539: 11,12 (JCRB; PubMed=25877200; PubMed=25926053)
ST   D18S51: 15
ST   D21S11: 29
ST   D3S1358: 16
ST   D5S818: 11 (PubMed=25926053)
ST   D5S818: 11,12 (Cosmic-CLP; JCRB; PubMed=25877200)
ST   D7S820: 11,12
ST   D8S1179: 13
ST   FGA: 20,22
ST   Penta D: 9
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 20
DI   NCIt; C9383; Rectal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   73Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 38
//
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RT   targeted treatment in colorectal cell lines.";
RL   BMC Med. Genomics 5:66.1-66.15(2012).
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RT   clinically actionable kinase targets.";
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//