ID   NCI-H69
AC   CVCL_1579
SY   NCI-H-69; NCI H69; H69; H-69; NCIH69; NCI-HUT-69; H69/P; NCI-H69C; H69C; H69c
DR   BTO; BTO:0003022
DR   CLO; CLO_0003609
DR   CLO; CLO_0008105
DR   EFO; EFO_0002300
DR   CLDB; cl1552
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; HTB-119
DR   BioSample; SAMN03473085
DR   BioSample; SAMN10988132
DR   cancercelllines; CVCL_1579
DR   CCRID; 1101HUM-PUMC000358
DR   Cell_Model_Passport; SIDM01121
DR   ChEMBL-Cells; CHEMBL3307712
DR   ChEMBL-Targets; CHEMBL614805
DR   CLS; 300185
DR   Cosmic; 688027
DR   Cosmic; 713879
DR   Cosmic; 755459
DR   Cosmic; 801610
DR   Cosmic; 808518
DR   Cosmic; 844545
DR   Cosmic; 844817
DR   Cosmic; 876167
DR   Cosmic; 877351
DR   Cosmic; 918010
DR   Cosmic; 929160
DR   Cosmic; 1006522
DR   Cosmic; 1021849
DR   Cosmic; 1152461
DR   Cosmic; 1175859
DR   Cosmic; 1212189
DR   Cosmic; 1219096
DR   Cosmic; 1239934
DR   Cosmic; 1434964
DR   Cosmic; 1571755
DR   Cosmic; 1609516
DR   Cosmic; 1995588
DR   Cosmic; 1998272
DR   Cosmic; 2125215
DR   Cosmic; 2239080
DR   Cosmic; 2648017
DR   Cosmic; 2668341
DR   Cosmic-CLP; 688027
DR   DepMap; ACH-000358
DR   ECACC; 91091802
DR   EGA; EGAS00001000978
DR   GDSC; 688027
DR   GEO; GSM169443
DR   GEO; GSM380498
DR   GEO; GSM536334
DR   GEO; GSM784197
DR   GEO; GSM794269
DR   GEO; GSM827305
DR   GEO; GSM845550
DR   GEO; GSM844659
DR   GEO; GSM887442
DR   GEO; GSM888522
DR   GEO; GSM1670258
DR   IARC_TP53; 328
DR   IGRhCellID; NCIH69
DR   IZSLER; BS TCL 172
DR   KCLB; 30119
DR   LiGeA; CCLE_927
DR   LINCS_LDP; LCL-1859
DR   NCI-DTP; NCI-H69
DR   PharmacoDB; NCIH69_1129_2019
DR   PRIDE; PXD011896
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1579
DR   PubChem_Cell_line; CVCL_1579
DR   Wikidata; Q38568854
RX   PubMed=1662924;
RX   PubMed=1845952;
RX   PubMed=1847845;
RX   PubMed=2388294;
RX   PubMed=2473086;
RX   PubMed=2574988;
RX   PubMed=2594029;
RX   PubMed=2985257;
RX   PubMed=2985258;
RX   PubMed=2986243;
RX   PubMed=3034934;
RX   PubMed=3335022;
RX   PubMed=6108156;
RX   PubMed=6148444;
RX   PubMed=6270685;
RX   PubMed=6272398;
RX   PubMed=6713399;
RX   PubMed=7736387;
RX   PubMed=7903701;
RX   PubMed=8626706;
RX   PubMed=8712684;
RX   PubMed=8784480;
RX   PubMed=8806092;
RX   PubMed=8806103;
RX   PubMed=9212023;
RX   PubMed=9413215;
RX   PubMed=9559344;
RX   PubMed=9744504;
RX   PubMed=9815546;
RX   PubMed=10037197;
RX   PubMed=10358721;
RX   PubMed=10536175;
RX   PubMed=11005564;
RX   PubMed=11030152;
RX   PubMed=11414198;
RX   PubMed=12569360;
RX   PubMed=17426248;
RX   PubMed=19394761;
RX   PubMed=19472407;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=20557307;
RX   PubMed=20615970;
RX   PubMed=22460905;
RX   PubMed=22961666;
RX   PubMed=23716474;
RX   PubMed=25877200;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28196595;
RX   PubMed=30038707;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31803961;
RX   PubMed=35839778;
WW   https://tcpaportal.org/mclp/
WW   https://www.atcc.org/en/support/technical-support/faqs/htb-119-morphology-and-culture-conditions
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: Caucasian.
CC   Doubling time: 56.0 hours (PubMed=1662924).
CC   HLA typing: A*02:01,23:01; B*42:02,58:05; C*07:01,14:02 (PubMed=26589293).
CC   HLA typing: A*02:01:01,23:01:01; B*01:01:01,51:01:01; C*07:01:01,14:02:01; DPB1*01:01:01G,03:01:01G; DQA1*03:01:01;03:03:01; DQB1*03:02:01; DRB1*04:04:01,04:05:01 (CLS=300185).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (PubMed=19394761; ATCC).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (PubMed=2594029; ATCC).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (PubMed=10536175; PubMed=20557307; ATCC).
CC   Omics: Array-based CGH.
CC   Omics: Deep exome analysis.
CC   Omics: Deep proteome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Genome ancestry: African=0.79%; Native American=0%; East Asian, North=1.48%; East Asian, South=0%; South Asian=0.42%; European, North=61.96%; European, South=35.34% (PubMed=30894373).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): ATCC; CCRID; CLS; Cosmic-CLP; ECACC; KCLB; PubMed=25877200
ST   Amelogenin: X (CLS)
ST   Amelogenin: X,Y (ATCC; CCRID; Cosmic-CLP; ECACC; KCLB; PubMed=25877200)
ST   CSF1PO: 10,12 (ATCC; CLS; ECACC; KCLB)
ST   CSF1PO: 10,12,13 (CCRID)
ST   CSF1PO: 10,13 (Cosmic-CLP; PubMed=25877200)
ST   D13S317: 12
ST   D16S539: 11
ST   D18S51: 12 (CLS)
ST   D18S51: 12,15 (CCRID; PubMed=25877200)
ST   D19S433: 15,15.2
ST   D21S11: 30,31.2
ST   D2S1338: 17
ST   D3S1358: 16
ST   D5S818: 11,13
ST   D7S820: 9
ST   D8S1179: 13
ST   FGA: 24
ST   Penta D: 9,11
ST   Penta E: 12
ST   TH01: 8,9
ST   TPOX: 10
ST   vWA: 16,17 (ATCC; CCRID; CLS; ECACC; KCLB)
ST   vWA: 17 (Cosmic-CLP; PubMed=25877200)
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 45
//
RX   PubMed=1662924;
RA   Khan M.Z., Freshney R.I., Murray A.M.B., Merry S., Plumb J.A.,
RA   McNicol A.M.;
RT   "Identification and characterisation in vitro of cells with a non-SCLC
RT   cell-like phenotype derived from a continuous SCLC cell line.";
RL   Anticancer Res. 11:1687-1695(1991).
//
RX   PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y;
RA   Broers J.L.V., Mijnheere E.P., Rot M.K., Schaart G., Sijlmans A.,
RA   Boerman O.C., Ramaekers F.C.S.;
RT   "Novel antigens characteristic of neuroendocrine malignancies.";
RL   Cancer 67:619-633(1991).
//
RX   PubMed=1847845; DOI=10.1007/BF00685110;
RA   Sasaki Y., Shinkai T., Eguchi K., Tamura T., Ohe Y., Ohmori T.,
RA   Saijo N.;
RT   "Prediction of the antitumor activity of new platinum analogs based on
RT   their ex vivo pharmacodynamics as determined by bioassay.";
RL   Cancer Chemother. Pharmacol. 27:263-270(1991).
//
RX   PubMed=2388294; DOI=10.1093/jnci/82.17.1420;
RA   McLemore T.L., Litterst C.L., Coudert B.P., Liu M.C., Hubbard W.C.,
RA   Adelberg S., Czerwinski M.J., McMahon N.A., Eggleston J.C., Boyd M.R.;
RT   "Metabolic activation of 4-ipomeanol in human lung, primary pulmonary
RT   carcinomas, and established human pulmonary carcinoma cell lines.";
RL   J. Natl. Cancer Inst. 82:1420-1426(1990).
//
RX   PubMed=2473086; DOI=10.1242/jcs.91.1.91;
RA   Broers J.L.V., Rot M.K., Oostendorp T., Bepler G., de Leij L.F.M.H.,
RA   Carney D.N., Vooijs G.P., Ramaekers F.C.S.;
RT   "Spontaneous changes in intermediate filament protein expression
RT   patterns in lung cancer cell lines.";
RL   J. Cell Sci. 91:91-108(1988).
//
RX   PubMed=2574988; DOI=10.1038/bjc.1989.376;
RA   Jensen P.B., Vindelov L.L., Roed H., Demant E.J.F., Sehested M.,
RA   Skovsgaard T., Hansen H.H.;
RT   "In vitro evaluation of the potential of aclarubicin in the treatment
RT   of small cell carcinoma of the lung (SCCL).";
RL   Br. J. Cancer 60:838-844(1989).
//
RX   PubMed=2594029; DOI=10.1056/NEJM198912213212501;
RA   Yandell D.W., Campbell T.A., Dayton S.H., Petersen R., Walton D.,
RA   Little J.B., McConkie-Rosell A., Buckley E.G., Dryja T.P.;
RT   "Oncogenic point mutations in the human retinoblastoma gene: their
RT   application to genetic counseling.";
RL   N. Engl. J. Med. 321:1689-1695(1989).
//
RX   PubMed=2985257;
RA   Carney D.N., Gazdar A.F., Bepler G., Guccion J.G., Marangos P.J.,
RA   Moody T.W., Zweig M.H., Minna J.D.;
RT   "Establishment and identification of small cell lung cancer cell lines
RT   having classic and variant features.";
RL   Cancer Res. 45:2913-2923(1985).
//
RX   PubMed=2985258;
RA   Gazdar A.F., Carney D.N., Nau M.M., Minna J.D.;
RT   "Characterization of variant subclasses of cell lines derived from
RT   small cell lung cancer having distinctive biochemical, morphological,
RT   and growth properties.";
RL   Cancer Res. 45:2924-2930(1985).
//
RX   PubMed=2986243; DOI=10.1007/978-3-642-82372-5_4;
RA   Whang-Peng J., Lee E.C.;
RT   "Cytogenetics of human small cell lung cancer.";
RL   Recent Results Cancer Res. 97:37-46(1985).
//
RX   PubMed=3034934; DOI=10.1002/jcb.240330405;
RA   Ibson J.M., Waters J.J., Twentyman P.R., Bleehen N.M., Rabbitts P.H.;
RT   "Oncogene amplification and chromosomal abnormalities in small cell
RT   lung cancer.";
RL   J. Cell. Biochem. 33:267-288(1987).
//
RX   PubMed=3335022;
RA   Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J.,
RA   Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.;
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=6108156;
RA   Gazdar A.F., Carney D.N., Russell E.K., Sims H.L., Baylin S.B.,
RA   Bunn P.A. Jr., Guccion J.G., Minna J.D.;
RT   "Establishment of continuous, clonable cultures of small-cell
RT   carcinoma of lung which have amine precursor uptake and
RT   decarboxylation cell properties.";
RL   Cancer Res. 40:3502-3507(1980).
//
RX   PubMed=6148444; DOI=10.1093/jnci/73.4.801;
RA   Morstyn G., Russo A., Carney D.N., Karawya E., Wilson S.H.,
RA   Mitchell J.B.;
RT   "Heterogeneity in the radiation survival curves and biochemical
RT   properties of human lung cancer cell lines.";
RL   J. Natl. Cancer Inst. 73:801-807(1984).
//
RX   PubMed=6270685; DOI=10.1073/pnas.78.7.4591;
RA   Cuttitta F., Rosen S.T., Gazdar A.F., Minna J.D.;
RT   "Monoclonal antibodies that demonstrate specificity for several types
RT   of human lung cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:4591-4595(1981).
//
RX   PubMed=6272398; DOI=10.1126/science.6272398;
RA   Moody T.W., Pert C.B., Gazdar A.F., Carney D.N., Minna J.D.;
RT   "High levels of intracellular bombesin characterize human small-cell
RT   lung carcinoma.";
RL   Science 214:1246-1248(1981).
//
RX   PubMed=6713399;
RA   Rosen S.T., Mulshine J.L., Cuttitta F., Fedorko J., Carney D.N.,
RA   Gazdar A.F., Minna J.D.;
RT   "Analysis of human small cell lung cancer differentiation antigens
RT   using a panel of rat monoclonal antibodies.";
RL   Cancer Res. 44:2052-2061(1984).
//
RX   PubMed=7736387; DOI=10.1002/1097-0142(19950515)75:10<2442::AID-CNCR2820751009>3.0.CO;2-Q;
RA   Campling B.G., Sarda I.R., Baer K.A., Pang S.C., Baker H.M.,
RA   Lofters W.S., Flynn T.G.;
RT   "Secretion of atrial natriuretic peptide and vasopressin by small cell
RT   lung cancer.";
RL   Cancer 75:2442-2451(1995).
//
RX   PubMed=7903701; DOI=10.1093/jnci/86.2.110;
RA   Barrand M.A., Heppell-Parton A.C., Wright K.A., Rabbitts P.H.,
RA   Twentyman P.R.;
RT   "A 190-kilodalton protein overexpressed in
RT   non-P-glycoprotein-containing multidrug-resistant cells and its
RT   relationship to the MRP gene.";
RL   J. Natl. Cancer Inst. 86:110-117(1994).
//
RX   PubMed=8626706; DOI=10.1074/jbc.271.19.11477;
RA   Quinn K.A., Treston A.M., Unsworth E.J., Miller M.-J., Vos M.,
RA   Grimley C., Battey J., Mulshine J.L., Cuttitta F.;
RT   "Insulin-like growth factor expression in human cancer cell lines.";
RL   J. Biol. Chem. 271:11477-11483(1996).
//
RX   PubMed=8712684;
RA   Khan M.Z., McNicol A.M., Freshney R.I.;
RT   "Tumorigenicity, invasion and metastasis of the small cell lung cancer
RT   cell line NCI-H69 and two derivative lines MOG-H69V and MOG-H69VZ.";
RL   Anticancer Res. 16:1659-1669(1996).
//
RX   PubMed=8784480; DOI=10.1159/000227600;
RA   Shinohara A., Shimizu E., Takada M., Sone S.;
RT   "Lack of c-mpl proto-oncogene transcripts and growth-stimulatory
RT   effects of thrombopoietin on human small cell lung cancer cell
RT   lines.";
RL   Oncology 53:426-434(1996).
//
RX   PubMed=8806092; DOI=10.1002/jcb.240630505;
RA   Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P.,
RA   McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr.,
RA   Carney D.N., Minna J.D., Mulshine J.L.;
RT   "NCI-Navy Medical Oncology Branch cell line data base.";
RL   J. Cell. Biochem. 63 Suppl. 24:32-91(1996).
//
RX   PubMed=8806103; DOI=10.1002/jcb.240630516;
RA   Johnson B.E., Russell E., Simmons A.M., Phelps R.M., Steinberg S.M.,
RA   Ihde D.C., Gazdar A.F.;
RT   "MYC family DNA amplification in 126 tumor cell lines from patients
RT   with small cell lung cancer.";
RL   J. Cell. Biochem. 63 Suppl. 24:210-217(1996).
//
RX   PubMed=9212023; DOI=10.1016/S0360-3016(97)00245-9;
RA   Krarup M., Poulsen H.S., Spang-Thomsen M.;
RT   "Cellular radiosensitivity of small-cell lung cancer cell lines.";
RL   Int. J. Radiat. Oncol. Biol. Phys. 38:191-196(1997).
//
RX   PubMed=9413215;
RA   Yamane H., Kiura K., Tabata M., Bessho A., Tsuchida T., Motoda K.,
RA   Hiraki A., Ueoka H., Harada M.;
RT   "Small cell lung cancer can express CD34 antigen.";
RL   Anticancer Res. 17:3627-3632(1997).
//
RX   PubMed=9559344; DOI=10.1002/(SICI)1098-2264(199804)21:4<326::AID-GCC6>3.0.CO;2-0;
RA   Mulligan L.M., Timmer T., Ivanchuk S.M., Campling B.G., Young L.C.,
RA   Rabbitts P.H., Sundaresan V., Hofstra R.M.W., Eng C.;
RT   "Investigation of the genes for RET and its ligand complex, GDNF/GFR
RT   alpha-I, in small cell lung carcinoma.";
RL   Genes Chromosomes Cancer 21:326-332(1998).
//
RX   PubMed=9744504; DOI=10.1038/bjc.1998.553;
RA   Damstrup L., Voldborg B.G.R., Spang-Thomsen M., Brunner N.,
RA   Poulsen H.S.;
RT   "In vitro invasion of small-cell lung cancer cell lines correlates
RT   with expression of epidermal growth factor receptor.";
RL   Br. J. Cancer 78:631-640(1998).
//
RX   PubMed=9815546;
RA   Campling B.G., Young L.C., Baer K.A., Lam Y.-M., Deeley R.G.,
RA   Cole S.P.C., Gerlach J.H.;
RT   "Expression of the MRP and MDR1 multidrug resistance genes in small
RT   cell lung cancer.";
RL   Clin. Cancer Res. 3:115-122(1997).
//
RX   PubMed=10037197;
RA   Tang X.X., Brodeur G.M., Campling B.G., Ikegaki N.;
RT   "Coexpression of transcripts encoding EPHB receptor protein tyrosine
RT   kinases and their ephrin-B ligands in human small cell lung
RT   carcinoma.";
RL   Clin. Cancer Res. 5:455-460(1999).
//
RX   PubMed=10358721; DOI=10.18926/AMO/31626;
RA   Matsushita A., Tabata M., Ueoka H., Kiura K., Shibayama T., Aoe K.,
RA   Kohara H., Harada M.;
RT   "Establishment of a drug sensitivity panel using human lung cancer
RT   cell lines.";
RL   Acta Med. Okayama 53:67-75(1999).
//
RX   PubMed=10536175; DOI=10.3892/ijo.15.5.927;
RA   Fujita T., Kiyama M., Tomizawa Y., Kohno T., Yokota J.;
RT   "Comprehensive analysis of p53 gene mutation characteristics in lung
RT   carcinoma with special reference to histological subtypes.";
RL   Int. J. Oncol. 15:927-934(1999).
//
RX   PubMed=11005564; DOI=10.1038/sj.neo.7900094;
RA   Kohno T., Sato T., Takakura S., Takei K., Inoue K., Nishioka M.,
RA   Yokota J.;
RT   "Mutation and expression of the DCC gene in human lung cancer.";
RL   Neoplasia 2:300-305(2000).
//
RX   PubMed=11030152; DOI=10.1038/sj.onc.1203815;
RA   Modi S., Kubo A., Oie H.K., Coxon A.B., Rehmatulla A., Kaye F.J.;
RT   "Protein expression of the RB-related gene family and SV40 large T
RT   antigen in mesothelioma and lung cancer.";
RL   Oncogene 19:4632-4639(2000).
//
RX   PubMed=11414198; DOI=10.1007/s004320000207;
RA   Lahm H., Andre S., Hoeflich A., Fischer J.R., Sordat B., Kaltner H.,
RA   Wolf E., Gabius H.-J.;
RT   "Comprehensive galectin fingerprinting in a panel of 61 human tumor
RT   cell lines by RT-PCR and its implications for diagnostic and
RT   therapeutic procedures.";
RL   J. Cancer Res. Clin. Oncol. 127:375-386(2001).
//
RX   PubMed=12569360; DOI=10.1038/sj.onc.1206106;
RA   Funakoshi T., Tachibana I., Hoshida Y., Kimura H., Takeda Y.,
RA   Kijima T., Nishino K., Goto H., Yoneda T., Kumagai T., Osaki T.,
RA   Hayashi S., Aozasa K., Kawase I.;
RT   "Expression of tetraspanins in human lung cancer cells: frequent
RT   downregulation of CD9 and its contribution to cell motility in small
RT   cell lung cancer.";
RL   Oncogene 22:674-687(2003).
//
RX   PubMed=17426248; DOI=10.1158/1541-7786.MCR-06-0367;
RA   Olejniczak E.T., Van Sant C., Anderson M.G., Wang G., Tahir S.K.,
RA   Sauter G., Lesniewski R., Semizarov D.;
RT   "Integrative genomic analysis of small-cell lung carcinoma reveals
RT   correlates of sensitivity to bcl-2 antagonists and uncovers novel
RT   chromosomal gains.";
RL   Mol. Cancer Res. 5:331-339(2007).
//
RX   PubMed=19394761; DOI=10.1016/j.canlet.2009.03.038;
RA   Shibata T., Kokubu A., Tsuta K., Hirohashi S.;
RT   "Oncogenic mutation of PIK3CA in small cell lung carcinoma: a
RT   potential therapeutic target pathway for chemotherapy-resistant lung
RT   cancer.";
RL   Cancer Lett. 283:203-211(2009).
//
RX   PubMed=19472407; DOI=10.1002/humu.21028;
RA   Blanco R., Iwakawa R., Tang M.-Y., Kohno T., Angulo B., Pio R.,
RA   Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.;
RT   "A gene-alteration profile of human lung cancer cell lines.";
RL   Hum. Mutat. 30:1199-1206(2009).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x;
RA   Iwakawa R., Kohno T., Enari M., Kiyono T., Yokota J.;
RT   "Prevalence of human papillomavirus 16/18/33 infection and p53
RT   mutation in lung adenocarcinoma.";
RL   Cancer Sci. 101:1891-1896(2010).
//
RX   PubMed=20615970; DOI=10.1073/pnas.1008132107;
RA   Voortman J., Lee J.-H., Killian J.K., Suuriniemi M., Wang Y.-H.,
RA   Lucchi M., Smith W.I. Jr., Meltzer P.S., Wang Y.-S., Giaccone G.;
RT   "Array comparative genomic hybridization-based characterization of
RT   genetic alterations in pulmonary neuroendocrine tumors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:13040-13045(2010).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
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