ID NCI-H358 AC CVCL_1559 SY H358; H-358; NCIH358 DR BTO; BTO_0002835 DR CLO; CLO_0008085 DR EFO; EFO_0002291 DR CLDB; cl3656 DR AddexBio; C0016016/4968 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ATCC; CRL-5807 DR BioGRID_ORCS_Cell_line; 964 DR BioSample; SAMN03471313 DR BioSample; SAMN10987886 DR cancercelllines; CVCL_1559 DR CCRID; 1101HUM-PUMC000470 DR CCRID; 3101HUMSCSP583 DR CCRID; 3101HUMTCHu151 DR Cell_Model_Passport; SIDM00718 DR ChEMBL-Cells; CHEMBL3307543 DR ChEMBL-Targets; CHEMBL614135 DR CLS; 300430 DR Cosmic; 722039 DR Cosmic; 724875 DR Cosmic; 877106 DR Cosmic; 903573 DR Cosmic; 908465 DR Cosmic; 910563 DR Cosmic; 914944 DR Cosmic; 929970 DR Cosmic; 934545 DR Cosmic; 980963 DR Cosmic; 1004699 DR Cosmic; 1028934 DR Cosmic; 1032435 DR Cosmic; 1052333 DR Cosmic; 1146915 DR Cosmic; 1219075 DR Cosmic; 1239902 DR Cosmic; 1600603 DR Cosmic; 1741780 DR Cosmic; 1802307 DR Cosmic; 1870273 DR Cosmic; 1995575 DR Cosmic; 2042868 DR Cosmic; 2560229 DR Cosmic; 2630418 DR Cosmic; 2647632 DR Cosmic; 2668265 DR Cosmic-CLP; 908465 DR DepMap; ACH-000860 DR ECACC; 95111733 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR EGA; EGAS00001002554 DR FANTOM5_SSTAR; 10709-109H7 DR GDSC; 908465 DR GEO; GSM108849 DR GEO; GSM108850 DR GEO; GSM206491 DR GEO; GSM253398 DR GEO; GSM274731 DR GEO; GSM274732 DR GEO; GSM385520 DR GEO; GSM385531 DR GEO; GSM434257 DR GEO; GSM513937 DR GEO; GSM514321 DR GEO; GSM784251 DR GEO; GSM794285 DR GEO; GSM817072 DR GEO; GSM827468 DR GEO; GSM844648 DR GEO; GSM887427 DR GEO; GSM888507 DR GEO; GSM1374744 DR GEO; GSM1670241 DR IARC_TP53; 21571 DR IARC_TP53; 21723 DR IGRhCellID; NCIH358 DR KCLB; 25807 DR KCLB; 90358 DR LiGeA; CCLE_423 DR LINCS_LDP; LCL-1671 DR Lonza; 729 DR NCI-DTP; NCI-H358 DR PharmacoDB; NCIH358_1110_2019 DR PRIDE; PXD030304 DR Progenetix; CVCL_1559 DR PubChem_Cell_line; CVCL_1559 DR Wikidata; Q54908041 RX PubMed=1311061; RX PubMed=1565469; RX PubMed=2386953; RX PubMed=2388294; RX PubMed=3335022; RX PubMed=3940644; RX PubMed=7972006; RX PubMed=8806092; RX PubMed=8806101; RX PubMed=9649128; RX PubMed=11030152; RX PubMed=11369051; RX PubMed=11464291; RX PubMed=12068308; RX PubMed=18083107; RX PubMed=19472407; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=20557307; RX PubMed=22460905; RX PubMed=22961666; RX PubMed=24135919; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=29444439; RX PubMed=29681454; RX PubMed=30038707; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=31803961; RX PubMed=31978347; RX PubMed=34320349; RX PubMed=35117401; RX PubMed=35839778; WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/n/cell-lines-detail-368.html CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: MD Anderson Cell Lines Project. CC Part of: NCI RAS program mutant KRAS cell line panel. CC Population: Caucasian. CC Doubling time: 38 hours (Note=In RPMI 1640 + 10% FBS), 76 hours (Note=In ACL-3), 60 hours (Note=In ACL-3 + BSA) (PubMed=3940644); 38 hours (PubMed=29681454); 38 hours (ECACC=95111733). CC HLA typing: A*03:01,03:01; B*15:01,35:01; C*03:04,04:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (PubMed=1311061; PubMed=1565469; PubMed=20557307). CC Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Thr75Ala (c.223A>G); Zygosity=Heterozygous (PubMed=11464291; DepMap=ACH-000860). CC Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (PubMed=1311061; PubMed=9649128; PubMed=12068308). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics. CC Omics: Proteomics; 2DE-MS. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; PTM; Phosphorylation. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=3.45%; Native American=0%; East Asian, North=4.63%; East Asian, South=0%; South Asian=0%; European, North=56.1%; European, South=35.82% (PubMed=30894373). CC Caution: NCI-H358 and NCI-H358M (Cellosaurus=CVCL_JA53) could be identical. CC Misspelling: H1358; PubMed=1311061; Note=In table 1. CC Derived from site: In situ; Lung; UBERON=UBERON_0002048. CC Cell type: Club cell; CL=CL_0000158. ST Source(s): AddexBio=C0016016/4968; ATCC=CRL-5807; CCRID; CLS=300430; Cosmic-CLP=908465; ECACC=95111733; KCLB=25807; KCLB=90358; PubMed=25877200; Technion Genomics Center ST Amelogenin: X,Y ST CSF1PO: 11,12 ST D10S1248: 13,14 ST D12S391: 20 ST D13S317: 8,12 ST D16S539: 12,13 ST D18S51: 14 ST D19S433: 13,14 ST D1S1656: 15,15.3 ST D21S11: 28,30 ST D22S1045: 11,15 ST D2S1338: 17,23 ST D2S441: 11,15 ST D3S1358: 14,18 ST D5S818: 10,12 ST D6S1043: 14 ST D7S820: 10,11 ST D8S1179: 13,14 ST DYS391: 10 ST FGA: 20,21 ST Penta D: 10,13 ST Penta E: 18 ST TH01: 6 ST TPOX: 8,9 ST vWA: 17 DI NCIt; C2923; Minimally invasive lung adenocarcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG Age unspecified CA Cancer cell line DT Created: 04-04-12; Last updated: 14-08-25; Version: 51 CH CVCL_VK07 ! NCI-H358a CH CVCL_JA53 ! NCI-H358M // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=24135919; DOI=10.1038/ncomms3617; PMCID=PMC4107456; RA Balbin, O. Alejandro RA Prensner, John R. RA Sahu, Anirban RA Yocum, Anastasia RA Shankar, Sunita RA Malik, Rohit RA Fermin, Damian RA Dhanasekaran, Saravana M. RA Chandler, Benjamin RA Thomas, Dafydd RA Beer, David G. RA Cao, Xu-Hong RA Nesvizhskii, Alexey I. RA Chinnaiyan, Arul M. RT "Reconstructing targetable pathways in lung cancer by integrating RT diverse omics data."; RL Nat. Commun. 4:2617.1-2617.13(2013). // RX PubMed=2386953; RA Gazdar, Adi F. RA Linnoila, Ritva Ilona RA Kurita, Yukio RA Oie, Herbert Kazuto RA Mulshine, James L. RA Clark, Jean C. RA Whitsett, Jeffrey A. RT "Peripheral airway cell differentiation in human lung cancer cell RT lines."; RL Cancer Res. 50:5481-5487(1990). // RX PubMed=11464291; DOI=10.1038/sj.onc.1204557; RA Shigemitsu, Kikuo RA Sekido, Yoshitaka RA Usami, Noriyasu RA Mori, Shoichi RA Sato, Mitsuo RA Horio, Yoshitsugu RA Hasegawa, Yoshinori RA Bader, Scott A. RA Gazdar, Adi F. RA Minna, John D. RA Hida, Toyoaki RA Yoshioka, Hiromu RA Imaizumi, Munehisa RA Ueda, Yuichi RA Takahashi, Masahide RA Shimokata, Kaoru RT "Genetic alteration of the beta-catenin gene (CTNNB1) in human lung RT cancer and malignant mesothelioma and identification of a new 3p21.3 RT homozygous deletion."; RL Oncogene 20:4249-4257(2001). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=18083107; DOI=10.1016/j.cell.2007.11.025; RA Rikova, Klarisa RA Guo, Ai-Lan RA Zeng, Qing-Fu RA Possemato, Anthony RA Yu, Jian RA Haack, Herbert RA Nardone, Julie RA Lee, Kimberly RA Reeves, Cynthia RA Li, Yu RA Hu, Ye-Rong RA Tan, Zhi-Ping RA Stokes, Matthew P. RA Sullivan, Laura RA Mitchell, Jeffrey RA Wetzel, Randy RA MacNeill, Joan RA Ren, Jian-Min RA Yuan, Jin RA Bakalarski, Corey E. RA Villen, Judit RA Kornhauser, Jon M. RA Smith, Bradley RA Li, Dai-Qiang RA Zhou, Xin-Min RA Gygi, Steven P. RA Gu, Ting-Lei RA Polakiewicz, Roberto D. RA Rush, John RA Comb, Michael J. RT "Global survey of phosphotyrosine signaling identifies oncogenic RT kinases in lung cancer."; RL Cell 131:1190-1203(2007). // RX PubMed=7972006; DOI=10.1073/pnas.91.23.11045; PMCID=PMC45163; RA Okamoto, Aikou RA Demetrick, Douglas J. RA Spillare, Elisa A. RA Hagiwara, Koichi RA Hussain, S. Perwez RA Bennett, William P. RA Forrester, Kathleen RA Gerwin, Brenda Isen RA Serrano, Manuel RA Beach, David H. RA Harris, Curtis Craig RT "Mutations and altered expression of p16INK4 in human cancer."; RL Proc. Natl. Acad. Sci. U.S.A. 91:11045-11049(1994). // RX PubMed=11030152; DOI=10.1038/sj.onc.1203815; RA Modi, Sanjay RA Kubo, Akihito RA Oie, Herbert Kazuto RA Coxon, Amy B. RA Rehmatulla, Ahad RA Kaye, Frederic J. RT "Protein expression of the RB-related gene family and SV40 large T RT antigen in mesothelioma and lung cancer."; RL Oncogene 19:4632-4639(2000). // RX PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x; PMCID=PMC11158680; RA Iwakawa, Reika RA Kohno, Takashi RA Enari, Masatoshi RA Kiyono, Tohru RA Yokota, Jun RT "Prevalence of human papillomavirus 16/18/33 infection and p53 RT mutation in lung adenocarcinoma."; RL Cancer Sci. 101:1891-1896(2010). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=1311061; RA Mitsudomi, Tetsuya RA Steinberg, Seth M. RA Nau, Marion M. RA Carbone, David P. RA D'Amico, Domenico RA Bodner, Sara M. RA Oie, Herbert Kazuto RA Linnoila, Ritva Ilona RA Mulshine, James L. RA Minna, John D. RA Gazdar, Adi F. RT "p53 gene mutations in non-small-cell lung cancer cell lines and their RT correlation with the presence of ras mutations and clinical RT features."; RL Oncogene 7:171-180(1992). // RX PubMed=8806101; DOI=10.1002/jcb.240630514; RA Lokshin, Anna E. RA Levitt, Mark L. RT "Effect of suramin on squamous differentiation and apoptosis in three RT human non-small-cell lung cancer cell lines."; RL J. Cell. Biochem. Suppl. 24:186-197(1996). // RX PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112; PMCID=PMC3567922; RA Byers, Lauren Averett RA Wang, Jing RA Nilsson, Monique B. RA Fujimoto, Junya RA Saintigny, Pierre RA Yordy, John Stuart RA Giri, Uma RA Peyton, Michael RA Fan, You-Hong RA Diao, Li-Xia RA Masrorpour, Fatemeh RA Shen, Li RA Liu, Wen-Bin RA Duchemann, Boris RA Tumula, Praveen RA Bhardwaj, Vikas RA Welsh, James RA Weber, Stephanie RA Glisson, Bonnie S. RA Kalhor, Neda RA Wistuba, Ignacio Ivan RA Girard, Luc RA Lippman, Scott M. RA Mills, Gordon B. RA Coombes, Kevin Robert RA Weinstein, John N. RA Minna, John D. RA Heymach, John Victor RT "Proteomic profiling identifies dysregulated pathways in small cell RT lung cancer and novel therapeutic targets including PARP1."; RL Cancer Discov. 2:798-811(2012). // RX PubMed=30038707; DOI=10.18632/oncotarget.25642; PMCID=PMC6049873; RA Du, Li-Qin RA Zhao, Zhen-Ze RA Suraokar, Milind Bhalchandra RA Shelton, Spencer S. RA Ma, Xiu-Ye RA Hsiao, Tzu-Hung RA Minna, John D. RA Wistuba, Ignacio Ivan RA Pertsemlidis, Alexander RT "LMO1 functions as an oncogene by regulating TTK expression and RT correlates with neuroendocrine differentiation of lung cancer."; RL Oncotarget 9:29601-29618(2018). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin K. RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=3335022; RA Alley, Michael C. RA Scudiero, Dominic A. RA Monks, Anne RA Hursey, Miriam L. RA Czerwinski, Maciej J. RA Fine, Donald L. RA Abbott, Betty Jane RA Mayo, Joseph G. RA Shoemaker, Robert H. RA Boyd, Michael R. RT "Feasibility of drug screening with panels of human tumor cell lines RT using a microculture tetrazolium assay."; RL Cancer Res. 48:589-601(1988). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084; RA Mulshine, James L. RA Ujhazy, Peter RA Antman, Melissa RA Burgess, Christine M. RA Kuzmin, Igor A. RA Bunn, Paul A. Jr. RA Johnson, Bruce E. RA Roth, Jack Alan RA Pass, Harvey I. RA Ross, Sheila M. RA Aldige, Carolyn R. RA Wistuba, Ignacio Ivan RA Minna, John D. RT "From clinical specimens to human cancer preclinical models -- a journey RT the NCI-cell line database-25 years later."; RL J. Cell. Biochem. 121:3986-3999(2020). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=3940644; RA Brower, Martin RA Carney, Desmond Niall RA Oie, Herbert Kazuto RA Gazdar, Adi F. RA Minna, John D. RT "Growth of cell lines and clinical specimens of human non-small cell RT lung cancer in a serum-free defined medium."; RL Cancer Res. 46:798-806(1986). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura E. RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=29681454; DOI=10.1016/j.cell.2018.03.028; PMCID=PMC5935540; RA McMillan, Elizabeth A. RA Ryu, Myung-Jeom RA Diep, Caroline H. RA Mendiratta, Saurabh RA Clemenceau, Jean Rene RA Vaden, Rachel M. RA Kim, Ju-Hwa RA Motoyaji, Takashi RA Covington, Kyle R. RA Peyton, Michael RA Huffman, Kenneth RA Wu, Xiao-Feng RA Girard, Luc RA Sung, Yeojin RA Chen, Pei-Hsaun RA Mallipeddi, Prema Latha RA Lee, Joo Young RA Hanson, Jordan RA Voruganti, Sukesh RA Yu, Yunku RA Park, Sunho RA Sudderth, Jessica RA DeSevo, Christopher RA Muzny, Donna M. RA Doddapaneni, HarshaVardhan RA Gazdar, Adi F. RA Gibbs, Richard Alexander RA Hwang, Tae Hyun RA Heymach, John Victor RA Wistuba, Ignacio Ivan RA Coombes, Kevin Robert RA Williams, Noelle S. RA Wheeler, David A. RA MacMillan, John B. RA DeBerardinis, Ralph J. RA Roth, Michael G. RA Posner, Bruce Arthur RA Minna, John D. RA Kim, Hyun Seok RA White, Michael A. RT "Chemistry-first approach for nomination of personalized treatment in RT lung cancer."; RL Cell 173:864-878.e29(2018). // RX PubMed=1565469; RA Bodner, Sara M. RA Minna, John D. RA Jensen, Sandra M. RA D'Amico, Domenico RA Carbone, David P. RA Mitsudomi, Tetsuya RA Fedorko, Joseph RA Buchhagen, Dotothy L. RA Nau, Marion M. RA Gazdar, Adi F. RA Linnoila, Ritva Ilona RT "Expression of mutant p53 proteins in lung cancer correlates with the RT class of p53 gene mutation."; RL Oncogene 7:743-749(1992). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, A. Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=8806092; DOI=10.1002/jcb.240630505; RA Phelps, Ruby M. RA Johnson, Bruce E. RA Ihde, Daniel C. RA Gazdar, Adi F. RA Carbone, David P. RA McClintock, Patrick R. RA Linnoila, Ritva Ilona RA Matthews, Mary J. RA Bunn, Paul A. Jr. RA Carney, Desmond Niall RA Minna, John D. RA Mulshine, James L. RT "NCI-Navy Medical Oncology Branch cell line data base."; RL J. Cell. Biochem. Suppl. 24:32-91(1996). // RX PubMed=11369051; DOI=10.1016/S0165-4608(00)00363-0; RA Luk, Catherine RA Tsao, Ming-Sound RA Bayani, Jane RA Shepherd, Frances Alice RA Squire, Jeremy Andrew RT "Molecular cytogenetic analysis of non-small cell lung carcinoma by RT spectral karyotyping and comparative genomic hybridization."; RL Cancer Genet. Cytogenet. 125:87-99(2001). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=34320349; DOI=10.1016/j.celrep.2021.109441; PMCID=PMC8333195; RA Jochems, Fleur RA Thijssen, Bram RA De Conti, Giulia RA Jansen, Robin RA Pogacar, Ziva RA Groot, Kelvin RA Wang, Li-Qin RA Schepers, Arnout RA Wang, Cun RA Jin, Hao-Jie RA Beijersbergen, Roderick L. RA Leite de Oliveira, Rodrigo RA Wessels, Lodewyk F.A. RA Bernards, Rene RT "The cancer SENESCopedia: a delineation of cancer cell senescence."; RL Cell Rep. 36:109441.1-109441.22(2021). // RX PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846; RA Blanco, Raquel RA Iwakawa, Reika RA Tang, Mo-Ying RA Kohno, Takashi RA Angulo, Barbara RA Pio, Ruben RA Montuenga, Luis M. RA Minna, John D. RA Yokota, Jun RA Sanchez-Cespedes, Montse RT "A gene-alteration profile of human lung cancer cell lines."; RL Hum. Mutat. 30:1199-1206(2009). // RX PubMed=12068308; DOI=10.1038/nature00766; RA Davies, Helen R. RA Bignell, Graham Robert RA Cox, Charles RA Stephens, Philip J. RA Edkins, Sarah RA Clegg, Sheila RA Teague, Jon W. RA Woffendin, Hayley RA Garnett, Mathew J. RA Bottomley, William RA Davis, Neil RA Dicks, Ed RA Ewing, Rebecca RA Floyd, Yvonne RA Gray, Kristian RA Hall, Sarah RA Hawes, Rachel RA Hughes, Jaime RA Kosmidou, Vivian RA Menzies, Andrew RA Mould, Catherine RA Parker, Adrian RA Stevens, Claire RA Watt, Stephen RA Hooper, Steven RA Wilson, Rebecca RA Jayatilake, Hiran RA Gusterson, Barry Austin RA Cooper, Colin S. RA Shipley, Janet M. RA Hargrave, Darren RA Pritchard-Jones, Kathy RA Maitland, Norman J. RA Chenevix-Trench, Georgia RA Riggins, Gregory J. RA Bigner, Darell Doty RA Palmieri, Giuseppe RA Cossu, Antonio RA Flanagan, Adrienne M. RA Nicholson, Andrew RA Ho, Judy W.C. RA Leung, Suet Yi RA Yuen, Siu Tsan RA Weber, Barbara L. RA Seigler, Hilliard Foster RA Darrow, Timothy L. RA Paterson, Hugh F. RA Marais, Richard RA Marshall, Christopher John RA Wooster, Richard RA Stratton, Michael Rudolf RA Futreal, P. Andrew RT "Mutations of the BRAF gene in human cancer."; RL Nature 417:949-954(2002). // RX PubMed=2388294; DOI=10.1093/jnci/82.17.1420; RA McLemore, Theodore L. RA Litterst, Charles L. RA Coudert, Bruno P. RA Liu, Mark C. RA Hubbard, Walter C. RA Adelberg, Steven RA Czerwinski, Maciej J. RA McMahon, Noreen A. RA Eggleston, Joseph C. RA Boyd, Michael R. RT "Metabolic activation of 4-ipomeanol in human lung, primary pulmonary RT carcinomas, and established human pulmonary carcinoma cell lines."; RL J. Natl. Cancer Inst. 82:1420-1426(1990). // RX PubMed=9649128; DOI=10.1038/bjc.1998.361; PMCID=PMC2150402; RA Yi, Seung RA Chen, Jing-Ru RA Viallet, Jean RA Schwall, Ralph H. RA Nakamura, T. RA Tsao, Ming-Sound RT "Paracrine effects of hepatocyte growth factor/scatter factor on RT non-small-cell lung carcinoma cell lines."; RL Br. J. Cancer 77:2162-2170(1998). // RX PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826; RA Yuan, Tina L. RA Amzallag, Arnaud RA Bagni, Rachel RA Yi, Ming RA Afghani, Shervin RA Burgan, William RA Fer, Nicole RA Strathern, Leslie A. RA Powell, Katie RA Smith, Brian RA Waters, Andrew Michael RA Drubin, David Alan RA Thomson, Ty RA Liao, Rosy RA Greninger, Patricia RA Stein, Giovanna T. RA Murchie, Ellen RA Cortez, Eliane RA Egan, Regina K. RA Procter, Lauren RA Bess, Matthew RA Cheng, Kwong Tai RA Lee, Chih-Shia RA Lee, Liam Changwoo RA Fellmann, Christof RA Stephens, Robert RA Luo, Ji RA Lowe, Scott William RA Benes, Cyril Henri RA McCormick, Frank RT "Differential effector engagement by oncogenic KRAS."; RL Cell Rep. 22:1889-1902(2018). // RX PubMed=35117401; DOI=10.21037/tcr.2019.12.04; PMCID=PMC8798965; RA Hou, Wen-Li RA Chang, Ming RA Liu, Xiao-Feng RA Hu, Lin-Sen RA Hua, Shu-Cheng RT "Proteomic and ultrastructural analysis of Clara cell and type II RT alveolar epithelial cell-type lung cancer cells."; RL Transl. Cancer Res. 9:565-576(2020). //