ID   NCI-H23
AC   CVCL_1547
SY   NCI.H23; NCI H23; H-23; H23; NCIH23
DR   BTO; BTO_0003238
DR   CLO; CLO_0008071
DR   EFO; EFO_0002286
DR   AddexBio; C0016005/4861
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-5800
DR   BioGRID_ORCS_Cell_line; 526
DR   BioSample; SAMN03471316
DR   BioSample; SAMN03471735
DR   BioSample; SAMN10988149
DR   cancercelllines; CVCL_1547
DR   CCRID; 3101HUMSCSP581
DR   Cell_Model_Passport; SIDM00138
DR   ChEMBL-Cells; CHEMBL3307750
DR   ChEMBL-Targets; CHEMBL614997
DR   CLS; 305044
DR   Cosmic; 687818
DR   Cosmic; 722038
DR   Cosmic; 801587
DR   Cosmic; 844829
DR   Cosmic; 852004
DR   Cosmic; 875849
DR   Cosmic; 876142
DR   Cosmic; 877237
DR   Cosmic; 905942
DR   Cosmic; 910561
DR   Cosmic; 914948
DR   Cosmic; 917993
DR   Cosmic; 953983
DR   Cosmic; 961834
DR   Cosmic; 974292
DR   Cosmic; 1004697
DR   Cosmic; 1089217
DR   Cosmic; 1092619
DR   Cosmic; 1146906
DR   Cosmic; 1154591
DR   Cosmic; 1175864
DR   Cosmic; 1188590
DR   Cosmic; 1219060
DR   Cosmic; 1239881
DR   Cosmic; 1305347
DR   Cosmic; 1312332
DR   Cosmic; 1436010
DR   Cosmic; 1802313
DR   Cosmic; 1870271
DR   Cosmic; 1995567
DR   Cosmic; 1998461
DR   Cosmic; 2058647
DR   Cosmic; 2125183
DR   Cosmic; 2433751
DR   Cosmic; 2630416
DR   Cosmic; 2647631
DR   Cosmic; 2648436
DR   Cosmic; 2668310
DR   Cosmic; 2772151
DR   Cosmic-CLP; 905942
DR   DepMap; ACH-000900
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   GDSC; 905942
DR   GEO; GSM2106
DR   GEO; GSM50214
DR   GEO; GSM50277
DR   GEO; GSM171868
DR   GEO; GSM171869
DR   GEO; GSM206487
DR   GEO; GSM253310
DR   GEO; GSM274790
DR   GEO; GSM274820
DR   GEO; GSM353232
DR   GEO; GSM385519
DR   GEO; GSM385530
DR   GEO; GSM434335
DR   GEO; GSM482108
DR   GEO; GSM513961
DR   GEO; GSM514346
DR   GEO; GSM743453
DR   GEO; GSM750803
DR   GEO; GSM794267
DR   GEO; GSM799341
DR   GEO; GSM799404
DR   GEO; GSM827478
DR   GEO; GSM844643
DR   GEO; GSM847075
DR   GEO; GSM887421
DR   GEO; GSM888500
DR   GEO; GSM1153412
DR   GEO; GSM1178456
DR   GEO; GSM1178457
DR   GEO; GSM1181268
DR   GEO; GSM1181312
DR   GEO; GSM1374733
DR   GEO; GSM1374734
DR   GEO; GSM1374735
DR   GEO; GSM1670229
DR   GEO; GSM2124674
DR   IARC_TP53; 256
DR   IGRhCellID; NCIH23
DR   KCLB; 90023
DR   LiGeA; CCLE_892
DR   LINCS_LDP; LCL-1619
DR   NCI-DTP; NCI-H23
DR   PharmacoDB; NCIH23_1085_2019
DR   PRIDE; PXD005942
DR   PRIDE; PXD005946
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1547
DR   PubChem_Cell_line; CVCL_1547
DR   SKY/M-FISH/CGH; 2796
DR   Wikidata; Q54907958
RX   PubMed=1311061;
RX   PubMed=1565469;
RX   PubMed=1845952;
RX   PubMed=2041050;
RX   PubMed=2473086;
RX   PubMed=3335022;
RX   PubMed=3940644;
RX   PubMed=6148444;
RX   PubMed=6270685;
RX   PubMed=6272398;
RX   PubMed=7718330;
RX   PubMed=8626706;
RX   PubMed=8806092;
RX   PubMed=9331090;
RX   PubMed=10358721;
RX   PubMed=10536175;
RX   PubMed=10700174;
RX   PubMed=11005564;
RX   PubMed=11030152;
RX   PubMed=12820372;
RX   PubMed=15471562;
RX   PubMed=15748285;
RX   PubMed=15900046;
RX   PubMed=17088437;
RX   PubMed=19153074;
RX   PubMed=19372543;
RX   PubMed=19472407;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=20557307;
RX   PubMed=22068913;
RX   PubMed=22336246;
RX   PubMed=22347499;
RX   PubMed=22384151;
RX   PubMed=22460905;
RX   PubMed=22628656;
RX   PubMed=22961666;
RX   PubMed=23381221;
RX   PubMed=23856246;
RX   PubMed=23933261;
RX   PubMed=24135919;
RX   PubMed=24279929;
RX   PubMed=24670534;
RX   PubMed=25120651;
RX   PubMed=25485619;
RX   PubMed=25714623;
RX   PubMed=25877200;
RX   PubMed=25984343;
RX   PubMed=26589293;
RX   PubMed=27377824;
RX   PubMed=27397505;
RX   PubMed=27602502;
RX   PubMed=27807467;
RX   PubMed=28196595;
RX   PubMed=29444439;
RX   PubMed=29681454;
RX   PubMed=29718670;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=31803961;
RX   PubMed=31978347;
RX   PubMed=35839778;
RX   PubMed=38861359;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
WW   Info; NCI DTP; NCI-60; https://dtp.cancer.gov/discovery_development/nci-60/cell_list.htm
WW   Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=6
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/n/cell-lines-detail-401.html
WW   Provider; BRICS; BRICS0118; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3922
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: JFCR39 cancer cell line panel.
CC   Part of: KuDOS 95 cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: NCI RAS program mutant KRAS cell line panel.
CC   Part of: NCI-60 cancer cell line panel.
CC   Part of: NCI-7 clinical proteomics reference material cell line panel.
CC   Population: African American.
CC   Doubling time: 38 hours (Note=In RPMI 1640 + 10% FBS), 71 hours (Note=In ACL-3), 57 hours (Note=In ACL-3 + BSA) (PubMed=3940644); 25 hours (PubMed=7718330); 35 hours (PubMed=25984343); 39.1 hours (PubMed=29681454); 38 hours (ATCC=CRL-5800); 33.4 hours (NCI-DTP=NCI-H23).
CC   HLA typing: A*80:01; B*50:01; C*06:02; DPB1*19:01; DQB1*06:03; DRB1*13:01:01 (PubMed=15748285).
CC   HLA typing: A*80:01,80:01; B*50:01,50:01; C*06:02,06:02; DQB1*06:13,06:13 (PubMed=26589293).
CC   Karyotypic information: Has lost chromosome Y (PubMed=25714623).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:795; ATM; Simple; p.Gln1919Pro (c.5756A>C); ClinVar=VCV000580726; Zygosity=Homozygous (PubMed=27602502).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (PubMed=1311061; PubMed=17088437).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Trp332Ter (c.996G>A); ClinVar=VCV000376339; Zygosity=Homozygous (PubMed=17088437).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Ile (c.738G>C); ClinVar=VCV001758655; Zygosity=Homozygous (PubMed=1311061; PubMed=9331090; PubMed=1565469; PubMed=10536175; PubMed=12820372; PubMed=15900046; PubMed=17088437; PubMed=20557307).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Metabolomics.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Phenotyping; Fluorescent probe library screening.
CC   Omics: Phenotyping; shRNA library screening.
CC   Omics: Proteomics.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; PTM; Phosphorylation.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; lncRNA profiling; RT-qPCR platform.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=67.86%; Native American=2.12%; East Asian, North=2.83%; East Asian, South=0%; South Asian=0%; European, North=10.88%; European, South=16.3% (PubMed=30894373).
CC   Misspelling: H63; PubMed=23381221; PubMed=25120651; Note=Confirmed by author personal communication.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
ST   Source(s): AddexBio=C0016005/4861; ATCC=CRL-5800; Cosmic-CLP=905942; KCLB=90023; PubMed=19372543; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 12
ST   D16S539: 9,11 (Cosmic-CLP=905942; PubMed=19372543; PubMed=25877200)
ST   D16S539: 11 (AddexBio=C0016005/4861; ATCC=CRL-5800)
ST   D18S51: 14,16
ST   D19S433: 12,14
ST   D21S11: 30
ST   D2S1338: 18,23
ST   D3S1358: 15
ST   D5S818: 12 (PubMed=25877200)
ST   D5S818: 12,13 (AddexBio=C0016005/4861; ATCC=CRL-5800; Cosmic-CLP=905942; KCLB=90023; PubMed=19372543)
ST   D7S820: 9,10
ST   D8S1179: 15
ST   FGA: 24
ST   Penta D: 8
ST   Penta E: 7,17
ST   TH01: 6
ST   TPOX: 8,9
ST   vWA: 16,17
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   51Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 48
//
RX   PubMed=1311061;
RA   Mitsudomi T., Steinberg S.M., Nau M.M., Carbone D.P., D'Amico D.,
RA   Bodner S.M., Oie H.K., Linnoila R.I., Mulshine J.L., Minna J.D.,
RA   Gazdar A.F.;
RT   "p53 gene mutations in non-small-cell lung cancer cell lines and their
RT   correlation with the presence of ras mutations and clinical
RT   features.";
RL   Oncogene 7:171-180(1992).
//
RX   PubMed=1565469;
RA   Bodner S.M., Minna J.D., Jensen S.M., D'Amico D., Carbone D.P.,
RA   Mitsudomi T., Fedorko J., Buchhagen D.L., Nau M.M., Gazdar A.F.,
RA   Linnoila R.I.;
RT   "Expression of mutant p53 proteins in lung cancer correlates with the
RT   class of p53 gene mutation.";
RL   Oncogene 7:743-749(1992).
//
RX   PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y;
RA   Broers J.L.V., Mijnheere E.P., Rot M.K., Schaart G., Sijlmans A.,
RA   Boerman O.C., Ramaekers F.C.S.;
RT   "Novel antigens characteristic of neuroendocrine malignancies.";
RL   Cancer 67:619-633(1991).
//
RX   PubMed=2041050; DOI=10.1093/jnci/83.11.757;
RA   Monks A., Scudiero D.A., Skehan P., Shoemaker R.H., Paull K.D.,
RA   Vistica D.T., Hose C.D., Langley J., Cronise P., Vaigro-Wolff A.,
RA   Gray-Goodrich M., Campbell H., Mayo J.G., Boyd M.R.;
RT   "Feasibility of a high-flux anticancer drug screen using a diverse
RT   panel of cultured human tumor cell lines.";
RL   J. Natl. Cancer Inst. 83:757-766(1991).
//
RX   PubMed=2473086; DOI=10.1242/jcs.91.1.91;
RA   Broers J.L.V., Rot M.K., Oostendorp T., Bepler G., de Leij L.F.M.H.,
RA   Carney D.N., Vooijs G.P., Ramaekers F.C.S.;
RT   "Spontaneous changes in intermediate filament protein expression
RT   patterns in lung cancer cell lines.";
RL   J. Cell Sci. 91:91-108(1988).
//
RX   PubMed=3335022;
RA   Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J.,
RA   Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.;
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=3940644;
RA   Brower M., Carney D.N., Oie H.K., Gazdar A.F., Minna J.D.;
RT   "Growth of cell lines and clinical specimens of human non-small cell
RT   lung cancer in a serum-free defined medium.";
RL   Cancer Res. 46:798-806(1986).
//
RX   PubMed=6148444; DOI=10.1093/jnci/73.4.801;
RA   Morstyn G., Russo A., Carney D.N., Karawya E., Wilson S.H. Jr.,
RA   Mitchell J.B.;
RT   "Heterogeneity in the radiation survival curves and biochemical
RT   properties of human lung cancer cell lines.";
RL   J. Natl. Cancer Inst. 73:801-807(1984).
//
RX   PubMed=6270685; DOI=10.1073/pnas.78.7.4591; PMCID=PMC319839;
RA   Cuttitta F., Rosen S.T., Gazdar A.F., Minna J.D.;
RT   "Monoclonal antibodies that demonstrate specificity for several types
RT   of human lung cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:4591-4595(1981).
//
RX   PubMed=6272398; DOI=10.1126/science.6272398;
RA   Moody T.W., Pert C.B., Gazdar A.F., Carney D.N., Minna J.D.;
RT   "High levels of intracellular bombesin characterize human small-cell
RT   lung carcinoma.";
RL   Science 214:1246-1248(1981).
//
RX   PubMed=7718330; DOI=10.1016/0959-8049(94)00472-H;
RA   Baguley B.C., Marshall E.S., Whittaker J.R., Dotchin M.C., Nixon J.,
RA   McCrystal M.R., Finlay G.J., Matthews J.H.L., Holdaway K.M.,
RA   van Zijl P.L.;
RT   "Resistance mechanisms determining the in vitro sensitivity to
RT   paclitaxel of tumour cells cultured from patients with ovarian
RT   cancer.";
RL   Eur. J. Cancer 31A:230-237(1995).
//
RX   PubMed=8626706; DOI=10.1074/jbc.271.19.11477;
RA   Quinn K.A., Treston A.M., Unsworth E.J., Miller M.-J., Vos M.,
RA   Grimley C., Battey J., Mulshine J.L., Cuttitta F.;
RT   "Insulin-like growth factor expression in human cancer cell lines.";
RL   J. Biol. Chem. 271:11477-11483(1996).
//
RX   PubMed=8806092; DOI=10.1002/jcb.240630505;
RA   Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P.,
RA   McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr.,
RA   Carney D.N., Minna J.D., Mulshine J.L.;
RT   "NCI-Navy Medical Oncology Branch cell line data base.";
RL   J. Cell. Biochem. Suppl. 24:32-91(1996).
//
RX   PubMed=9331090;
RA   O'Connor P.M., Jackman J., Bae I., Myers T.G., Fan S.-J., Mutoh M.,
RA   Scudiero D.A., Monks A., Sausville E.A., Weinstein J.N., Friend S.H.,
RA   Fornace A.J. Jr., Kohn K.W.;
RT   "Characterization of the p53 tumor suppressor pathway in cell lines of
RT   the National Cancer Institute anticancer drug screen and correlations
RT   with the growth-inhibitory potency of 123 anticancer agents.";
RL   Cancer Res. 57:4285-4300(1997).
//
RX   PubMed=10358721; DOI=10.18926/AMO/31626;
RA   Matsushita A., Tabata M., Ueoka H., Kiura K., Shibayama T., Aoe K.,
RA   Kohara H., Harada M.;
RT   "Establishment of a drug sensitivity panel using human lung cancer
RT   cell lines.";
RL   Acta Med. Okayama 53:67-75(1999).
//
RX   PubMed=10536175; DOI=10.3892/ijo.15.5.927;
RA   Fujita T., Kiyama M., Tomizawa Y., Kohno T., Yokota J.;
RT   "Comprehensive analysis of p53 gene mutation characteristics in lung
RT   carcinoma with special reference to histological subtypes.";
RL   Int. J. Oncol. 15:927-934(1999).
//
RX   PubMed=10700174; DOI=10.1038/73432;
RA   Ross D.T., Scherf U., Eisen M.B., Perou C.M., Rees C., Spellman P.T.,
RA   Iyer V.R., Jeffrey S.S., van de Rijn M., Waltham M.C., Pergamenschikov A.,
RA   Lee J.C.F., Lashkari D., Shalon D., Myers T.G., Weinstein J.N.,
RA   Botstein D., Brown P.O.;
RT   "Systematic variation in gene expression patterns in human cancer cell
RT   lines.";
RL   Nat. Genet. 24:227-235(2000).
//
RX   PubMed=11005564; DOI=10.1038/sj.neo.7900094; PMCID=PMC1550293;
RA   Kohno T., Sato T., Takakura S., Takei K., Inoue K., Nishioka M.,
RA   Yokota J.;
RT   "Mutation and expression of the DCC gene in human lung cancer.";
RL   Neoplasia 2:300-305(2000).
//
RX   PubMed=11030152; DOI=10.1038/sj.onc.1203815;
RA   Modi S., Kubo A., Oie H.K., Coxon A.B., Rehmatulla A., Kaye F.J.;
RT   "Protein expression of the RB-related gene family and SV40 large T
RT   antigen in mesothelioma and lung cancer.";
RL   Oncogene 19:4632-4639(2000).
//
RX   PubMed=12820372;
RA   Bergqvist M., Brattstrom D., Gullbo J., Hesselius P., Brodin O.,
RA   Wagenius G.;
RT   "p53 status and its in vitro relationship to radiosensitivity and
RT   chemosensitivity in lung cancer.";
RL   Anticancer Res. 23:1207-1212(2003).
//
RX   PubMed=15471562; DOI=10.1111/j.1349-7006.2004.tb03257.x; PMCID=PMC11158492;
RA   Achiwa H., Oguri T., Sato S., Maeda H., Niimi T., Ueda R.;
RT   "Determinants of sensitivity and resistance to gemcitabine: the roles
RT   of human equilibrative nucleoside transporter 1 and deoxycytidine
RT   kinase in non-small cell lung cancer.";
RL   Cancer Sci. 95:753-757(2004).
//
RX   PubMed=15748285; DOI=10.1186/1479-5876-3-11; PMCID=PMC555742;
RA   Adams S., Robbins F.-M., Chen D., Wagage D., Holbeck S.L.,
RA   Morse H.C. 3rd, Stroncek D., Marincola F.M.;
RT   "HLA class I and II genotype of the NCI-60 cell lines.";
RL   J. Transl. Med. 3:11.1-11.8(2005).
//
RX   PubMed=15900046; DOI=10.1093/jnci/dji133;
RA   Mashima T., Oh-hara T., Sato S., Mochizuki M., Sugimoto Y.,
RA   Yamazaki K., Hamada J.-i., Tada M., Moriuchi T., Ishikawa Y., Kato Y.,
RA   Tomoda H., Yamori T., Tsuruo T.;
RT   "p53-defective tumors with a functional apoptosome-mediated pathway: a
RT   new therapeutic target.";
RL   J. Natl. Cancer Inst. 97:765-777(2005).
//
RX   PubMed=17088437; DOI=10.1158/1535-7163.MCT-06-0433; PMCID=PMC2705832;
RA   Ikediobi O.N., Davies H.R., Bignell G.R., Edkins S., Stevens C.,
RA   O'Meara S., Santarius T., Avis T., Barthorpe S., Brackenbury L.,
RA   Buck G., Butler A.P., Clements J., Cole J., Dicks E., Forbes S.,
RA   Gray K., Halliday K., Harrison R., Hills K., Hinton J., Hunter C.,
RA   Jenkinson A., Jones D., Kosmidou V., Lugg R., Menzies A.,
RA   Mironenko T., Parker A., Perry J., Raine K.M., Richardson D.,
RA   Shepherd R., Small A., Smith R., Solomon H., Stephens P.J.,
RA   Teague J.W., Tofts C., Varian J., Webb T., West S., Widaa S., Yates A.,
RA   Reinhold W.C., Weinstein J.N., Stratton M.R., Futreal P.A., Wooster R.;
RT   "Mutation analysis of 24 known cancer genes in the NCI-60 cell line
RT   set.";
RL   Mol. Cancer Ther. 5:2606-2612(2006).
//
RX   PubMed=19153074; DOI=10.1093/hmg/ddp034;
RA   Medina P.P., Castillo S.D., Blanco S., Sanz-Garcia M., Largo C.,
RA   Alvarez S., Yokota J., Gonzalez-Neira A., Benitez J., Clevers H.C.,
RA   Cigudosa J.C., Lazo P.A., Sanchez-Cespedes M.;
RT   "The SRY-HMG box gene, SOX4, is a target of gene amplification at
RT   chromosome 6p in lung cancer.";
RL   Hum. Mol. Genet. 18:1343-1352(2009).
//
RX   PubMed=19372543; DOI=10.1158/1535-7163.MCT-08-0921; PMCID=PMC4020356;
RA   Lorenzi P.L., Reinhold W.C., Varma S., Hutchinson A.A., Pommier Y.,
RA   Chanock S.J., Weinstein J.N.;
RT   "DNA fingerprinting of the NCI-60 cell line panel.";
RL   Mol. Cancer Ther. 8:713-724(2009).
//
RX   PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846;
RA   Blanco R., Iwakawa R., Tang M.-Y., Kohno T., Angulo B., Pio R.,
RA   Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.;
RT   "A gene-alteration profile of human lung cancer cell lines.";
RL   Hum. Mutat. 30:1199-1206(2009).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x; PMCID=PMC11158680;
RA   Iwakawa R., Kohno T., Enari M., Kiyono T., Yokota J.;
RT   "Prevalence of human papillomavirus 16/18/33 infection and p53
RT   mutation in lung adenocarcinoma.";
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