ID   NCI-H226
AC   CVCL_1544
SY   NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226
DR   BTO; BTO_0003008
DR   CLO; CLO_0008068
DR   EFO; EFO_0002285
DR   AddexBio; C0016011/4916
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-5826
DR   BioGRID_ORCS_Cell_line; 960
DR   BioSample; SAMN03471987
DR   BioSample; SAMN10987668
DR   cancercelllines; CVCL_1544
DR   CCRID; 3101HUMTCHu235
DR   CCRID; 4201HUM-CCTCC00634
DR   Cell_Model_Passport; SIDM00139
DR   ChEMBL-Cells; CHEMBL3307697
DR   ChEMBL-Targets; CHEMBL614740
DR   CLS; 305091
DR   Cosmic; 733816
DR   Cosmic; 875850
DR   Cosmic; 877259
DR   Cosmic; 877402
DR   Cosmic; 886388
DR   Cosmic; 903570
DR   Cosmic; 905941
DR   Cosmic; 931374
DR   Cosmic; 974291
DR   Cosmic; 980961
DR   Cosmic; 1006539
DR   Cosmic; 1028953
DR   Cosmic; 1032433
DR   Cosmic; 1047100
DR   Cosmic; 1092618
DR   Cosmic; 1152497
DR   Cosmic; 1175863
DR   Cosmic; 1188585
DR   Cosmic; 1219111
DR   Cosmic; 1239951
DR   Cosmic; 1305346
DR   Cosmic; 1312331
DR   Cosmic; 1436011
DR   Cosmic; 1481544
DR   Cosmic; 1802319
DR   Cosmic; 1870270
DR   Cosmic; 1963326
DR   Cosmic; 1995565
DR   Cosmic; 1998460
DR   Cosmic; 2060522
DR   Cosmic; 2560228
DR   Cosmic; 2664122
DR   Cosmic; 2772152
DR   Cosmic-CLP; 905941
DR   DepMap; ACH-000367
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   ENCODE; ENCBS328RVB
DR   ENCODE; ENCBS986NWY
DR   FANTOM5_SSTAR; 10846-111E9
DR   GDSC; 905941
DR   GEO; GSM2123
DR   GEO; GSM50213
DR   GEO; GSM50276
DR   GEO; GSM62965
DR   GEO; GSM206486
DR   GEO; GSM274785
DR   GEO; GSM274821
DR   GEO; GSM743452
DR   GEO; GSM750820
DR   GEO; GSM794278
DR   GEO; GSM799340
DR   GEO; GSM799403
DR   GEO; GSM844640
DR   GEO; GSM844641
DR   GEO; GSM844642
DR   GEO; GSM847074
DR   GEO; GSM887416
DR   GEO; GSM888495
DR   GEO; GSM1153411
DR   GEO; GSM1178441
DR   GEO; GSM1178442
DR   GEO; GSM1178443
DR   GEO; GSM1181351
DR   GEO; GSM1374728
DR   GEO; GSM1374729
DR   GEO; GSM1374730
DR   GEO; GSM1670227
DR   GEO; GSM2124673
DR   IARC_TP53; 515
DR   IARC_TP53; 21406
DR   IARC_TP53; 23624
DR   IGRhCellID; NCIH226
DR   KCLB; 90226
DR   LiGeA; CCLE_131
DR   LINCS_LDP; LCL-1597
DR   Lonza; 839
DR   NCI-DTP; NCI-H226
DR   PharmacoDB; NCIH226_1082_2019
DR   PRIDE; PXD005942
DR   PRIDE; PXD005946
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1544
DR   PubChem_Cell_line; CVCL_1544
DR   SKY/M-FISH/CGH; 2802
DR   Wikidata; Q54907948
RX   PubMed=1311061;
RX   PubMed=1568228;
RX   PubMed=2041050;
RX   PubMed=2386953;
RX   PubMed=3335022;
RX   PubMed=6272398;
RX   PubMed=8806092;
RX   PubMed=8806101;
RX   PubMed=8956792;
RX   PubMed=9331090;
RX   PubMed=9488600;
RX   PubMed=9649128;
RX   PubMed=10700174;
RX   PubMed=11030152;
RX   PubMed=11369051;
RX   PubMed=15748285;
RX   PubMed=16187286;
RX   PubMed=17088437;
RX   PubMed=17332333;
RX   PubMed=17458138;
RX   PubMed=18083107;
RX   PubMed=19372543;
RX   PubMed=19472407;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=20557307;
RX   PubMed=22068913;
RX   PubMed=22336246;
RX   PubMed=22347499;
RX   PubMed=22384151;
RX   PubMed=22460905;
RX   PubMed=22628656;
RX   PubMed=22961666;
RX   PubMed=23856246;
RX   PubMed=23933261;
RX   PubMed=24002593;
RX   PubMed=24279929;
RX   PubMed=24670534;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25902174;
RX   PubMed=26589293;
RX   PubMed=27377824;
RX   PubMed=27397505;
RX   PubMed=27807467;
RX   PubMed=28196595;
RX   PubMed=29681454;
RX   PubMed=29718670;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31068700;
RX   PubMed=31803961;
RX   PubMed=31978347;
RX   PubMed=35839778;
RX   PubMed=38861359;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
WW   Info; NCI DTP; NCI-60; https://dtp.cancer.gov/discovery_development/nci-60/cell_list.htm
WW   Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=10
WW   Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/lung-cancer-xenograft/nci-h226-xenograft-model/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: JFCR39 cancer cell line panel.
CC   Part of: KuDOS 95 cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: NCI-60 cancer cell line panel.
CC   Part of: NCI-7 clinical proteomics reference material cell line panel.
CC   Population: Caucasian.
CC   Doubling time: 43 hours (PubMed=9488600); 52 hours (PubMed=29681454); 61 hours (NCI-DTP=NCI-H226).
CC   HLA typing: A*01:01:01,24:02:01; B*07,39; C*07:02:01,12:03:01; DPB1*02:01:02,04:01; DQB1*05:02:01,06:02; DRB1*15:01:01,16:01:01 (PubMed=15748285).
CC   HLA typing: A*01:01,24:02; B*07:02,39:01; C*07:02,12:03; DQB1*06:13,06:13; DRB1*15:01,15:01 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (ATCC=CRL-5826).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=1568228; PubMed=20557307).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Metabolomics.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Phenotyping; Fluorescent probe library screening.
CC   Omics: Proteomics.
CC   Omics: Proteomics; 2DE-MS.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; lncRNA profiling; RT-qPCR platform.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=0.16%; East Asian, South=0.88%; South Asian=1.48%; European, North=65.62%; European, South=31.86% (PubMed=30894373).
CC   Caution: Indicated to have a TP53 p.Arg158Leu (c.473G>T) mutation according to PubMed=1311061, but no TP53 mutation detected according to PubMed=20557307, CCLE and Cosmic-CLP.
CC   Discontinued: KCLB; 90226; probable.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): AddexBio=C0016011/4916; ATCC=CRL-5826; CCRID; Cosmic-CLP=905941; PubMed=19372543; PubMed=25877200
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D12S391: 22
ST   D13S317: 13,14
ST   D16S539: 9,12
ST   D18S51: 16
ST   D19S433: 15
ST   D21S11: 29,32.2
ST   D2S1338: 25
ST   D2S441: 14
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D6S1043: 13,18
ST   D7S820: 8,10
ST   D8S1179: 14,15
ST   FGA: 20,23
ST   Penta D: 9,10
ST   Penta E: 12,15
ST   TH01: 8,9.3
ST   TPOX: 8 (PubMed=19372543)
ST   TPOX: 8,11 (AddexBio=C0016011/4916; ATCC=CRL-5826; CCRID; Cosmic-CLP=905941; PubMed=25877200)
ST   vWA: 17
DI   NCIt; C45662; Pleural epithelioid mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 48
//
RX   PubMed=1311061;
RA   Mitsudomi, Tetsuya
RA   Steinberg, Seth M.
RA   Nau, Marion M.
RA   Carbone, David P.
RA   D'Amico, Domenico
RA   Bodner, Sara M.
RA   Oie, Herbert Kazuto
RA   Linnoila, Ritva Ilona
RA   Mulshine, James L.
RA   Minna, John D.
RA   Gazdar, Adi F.
RT   "p53 gene mutations in non-small-cell lung cancer cell lines and their
RT   correlation with the presence of ras mutations and clinical
RT   features.";
RL   Oncogene 7:171-180(1992).
//
RX   PubMed=1568228;
RA   Metcalf, Robert A.
RA   Welsh, Judith A.
RA   Bennett, William P.
RA   Seddon, Michael B.
RA   Lehman, Teresa A.
RA   Pelin-Enlund, Katarina
RA   Linnainmaa, Kaija
RA   Tammilehto, Lauri
RA   Mattson, Karin
RA   Gerwin, Brenda Isen
RA   Harris, Curtis Craig
RT   "p53 and Kirsten-ras mutations in human mesothelioma cell lines.";
RL   Cancer Res. 52:2610-2615(1992).
//
RX   PubMed=2041050; DOI=10.1093/jnci/83.11.757;
RA   Monks, Anne
RA   Scudiero, Dominic A.
RA   Skehan, Philip
RA   Shoemaker, Robert H.
RA   Paull, Kenneth D.
RA   Vistica, David T.
RA   Hose, Curtis D.
RA   Langley, John
RA   Cronise, Paul
RA   Vaigro-Wolff, Anne
RA   Gray-Goodrich, Marcia
RA   Campbell, Hugh
RA   Mayo, Joseph G.
RA   Boyd, Michael R.
RT   "Feasibility of a high-flux anticancer drug screen using a diverse
RT   panel of cultured human tumor cell lines.";
RL   J. Natl. Cancer Inst. 83:757-766(1991).
//
RX   PubMed=2386953;
RA   Gazdar, Adi F.
RA   Linnoila, Ritva Ilona
RA   Kurita, Yukio
RA   Oie, Herbert Kazuto
RA   Mulshine, James L.
RA   Clark, Jean C.
RA   Whitsett, Jeffrey A.
RT   "Peripheral airway cell differentiation in human lung cancer cell
RT   lines.";
RL   Cancer Res. 50:5481-5487(1990).
//
RX   PubMed=3335022;
RA   Alley, Michael C.
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Hursey, Miriam L.
RA   Czerwinski, Maciej J.
RA   Fine, Donald L.
RA   Abbott, Betty Jane
RA   Mayo, Joseph G.
RA   Shoemaker, Robert H.
RA   Boyd, Michael R.
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=6272398; DOI=10.1126/science.6272398;
RA   Moody, Terry W.
RA   Pert, Candace Beebe
RA   Gazdar, Adi F.
RA   Carney, Desmond Niall
RA   Minna, John D.
RT   "High levels of intracellular bombesin characterize human small-cell
RT   lung carcinoma.";
RL   Science 214:1246-1248(1981).
//
RX   PubMed=8806092; DOI=10.1002/jcb.240630505;
RA   Phelps, Ruby M.
RA   Johnson, Bruce E.
RA   Ihde, Daniel C.
RA   Gazdar, Adi F.
RA   Carbone, David P.
RA   McClintock, Patrick R.
RA   Linnoila, Ritva Ilona
RA   Matthews, Mary J.
RA   Bunn, Paul A. Jr.
RA   Carney, Desmond Niall
RA   Minna, John D.
RA   Mulshine, James L.
RT   "NCI-Navy Medical Oncology Branch cell line data base.";
RL   J. Cell. Biochem. Suppl. 24:32-91(1996).
//
RX   PubMed=8806101; DOI=10.1002/jcb.240630514;
RA   Lokshin, Anna E.
RA   Levitt, Mark L.
RT   "Effect of suramin on squamous differentiation and apoptosis in three
RT   human non-small-cell lung cancer cell lines.";
RL   J. Cell. Biochem. Suppl. 24:186-197(1996).
//
RX   PubMed=8956792; DOI=10.1038/bjc.1996.629; PMCID=PMC2077222;
RA   Fang, Kang
RT   "An enhanced and sensitive autocrine stimulation by transforming
RT   growth factor-alpha is acquired in the brain metastatic variant of a
RT   human non-small-cell lung cancer cell line.";
RL   Br. J. Cancer 74:1776-1782(1996).
//
RX   PubMed=9331090;
RA   O'Connor, Patrick M.
RA   Jackman, Joany
RA   Bae, Insoo
RA   Myers, Timothy Gene
RA   Fan, Sai-Jun
RA   Mutoh, Masato
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Sausville, Edward A.
RA   Weinstein, John N.
RA   Friend, Stephen H.
RA   Fornace, Albert J. Jr.
RA   Kohn, Kurt W.
RT   "Characterization of the p53 tumor suppressor pathway in cell lines of
RT   the National Cancer Institute anticancer drug screen and correlations
RT   with the growth-inhibitory potency of 123 anticancer agents.";
RL   Cancer Res. 57:4285-4300(1997).
//
RX   PubMed=9488600; DOI=10.1007/s002800050744;
RA   Ma, Jian-Guo
RA   Maliepaard, Marc
RA   Nooter, Kees
RA   Boersma, Antonius W.M.
RA   Verweij, Jaap
RA   Stoter, Gerrit
RA   Schellens, Jan H.M.
RT   "Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a
RT   panel of eight solid-tumor cell lines in vitro.";
RL   Cancer Chemother. Pharmacol. 41:307-316(1998).
//
RX   PubMed=9649128; DOI=10.1038/bjc.1998.361; PMCID=PMC2150402;
RA   Yi, Seung
RA   Chen, Jing-Ru
RA   Viallet, Jean
RA   Schwall, Ralph H.
RA   Nakamura, T.
RA   Tsao, Ming-Sound
RT   "Paracrine effects of hepatocyte growth factor/scatter factor on
RT   non-small-cell lung carcinoma cell lines.";
RL   Br. J. Cancer 77:2162-2170(1998).
//
RX   PubMed=10700174; DOI=10.1038/73432;
RA   Ross, Douglas T.
RA   Scherf, Uwe
RA   Eisen, Michael Bruce
RA   Perou, Charles M.
RA   Rees, Christian
RA   Spellman, Paul T.
RA   Iyer, Vishwanath R.
RA   Jeffrey, Stefanie S.
RA   van de Rijn, Matt
RA   Waltham, Mark C.
RA   Pergamenschikov, Alexander
RA   Lee, Jeffrey C.F.
RA   Lashkari, Deval
RA   Shalon, Dari
RA   Myers, Timothy Gene
RA   Weinstein, John N.
RA   Botstein, David
RA   Brown, Patrick O'Reilly
RT   "Systematic variation in gene expression patterns in human cancer cell
RT   lines.";
RL   Nat. Genet. 24:227-235(2000).
//
RX   PubMed=11030152; DOI=10.1038/sj.onc.1203815;
RA   Modi, Sanjay
RA   Kubo, Akihito
RA   Oie, Herbert Kazuto
RA   Coxon, Amy B.
RA   Rehmatulla, Ahad
RA   Kaye, Frederic J.
RT   "Protein expression of the RB-related gene family and SV40 large T
RT   antigen in mesothelioma and lung cancer.";
RL   Oncogene 19:4632-4639(2000).
//
RX   PubMed=11369051; DOI=10.1016/S0165-4608(00)00363-0;
RA   Luk, Catherine
RA   Tsao, Ming-Sound
RA   Bayani, Jane
RA   Shepherd, Frances Alice
RA   Squire, Jeremy Andrew
RT   "Molecular cytogenetic analysis of non-small cell lung carcinoma by
RT   spectral karyotyping and comparative genomic hybridization.";
RL   Cancer Genet. Cytogenet. 125:87-99(2001).
//
RX   PubMed=15748285; DOI=10.1186/1479-5876-3-11; PMCID=PMC555742;
RA   Adams, Sharon
RA   Robbins, Fu-Meei
RA   Chen, Deborah
RA   Wagage, Devika
RA   Holbeck, Susan L.
RA   Morse, Herbert Carpenter 3rd
RA   Stroncek, David
RA   Marincola, Francesco M.
RT   "HLA class I and II genotype of the NCI-60 cell lines.";
RL   J. Transl. Med. 3:11.1-11.8(2005).
//
RX   PubMed=16187286; DOI=10.1002/ijc.21491;
RA   Garnis, Cathie
RA   Lockwood, William W.
RA   Vucic, Emily
RA   Ge, Ying
RA   Girard, Luc
RA   Minna, John D.
RA   Gazdar, Adi F.
RA   Lam, Stephen
RA   MacAulay, Calum
RA   Lam, Wan L.
RT   "High resolution analysis of non-small cell lung cancer cell lines by
RT   whole genome tiling path array CGH.";
RL   Int. J. Cancer 118:1556-1564(2006).
//
RX   PubMed=17088437; DOI=10.1158/1535-7163.MCT-06-0433; PMCID=PMC2705832;
RA   Ikediobi, Ogechi N.
RA   Davies, Helen R.
RA   Bignell, Graham Robert
RA   Edkins, Sarah
RA   Stevens, Claire
RA   O'Meara, Sarah
RA   Santarius, Thomas
RA   Avis, Tim
RA   Barthorpe, Syd
RA   Brackenbury, Lisa
RA   Buck, Gemma
RA   Butler, Adam P.
RA   Clements, Jody
RA   Cole, Jennifer
RA   Dicks, Ed
RA   Forbes, Simon
RA   Gray, Kristian
RA   Halliday, Kelly
RA   Harrison, Rachel
RA   Hills, Katy
RA   Hinton, Jonathan
RA   Hunter, Chris
RA   Jenkinson, Andy
RA   Jones, David
RA   Kosmidou, Vivian
RA   Lugg, Richard
RA   Menzies, Andrew
RA   Mironenko, Tatiana
RA   Parker, Adrian
RA   Perry, Janet
RA   Raine, Keiran Martin
RA   Richardson, David
RA   Shepherd, Rebecca
RA   Small, Alex
RA   Smith, Raffaella
RA   Solomon, Helen
RA   Stephens, Philip J.
RA   Teague, Jon W.
RA   Tofts, Calli
RA   Varian, Jennifer
RA   Webb, Tony
RA   West, Sofie
RA   Widaa, Sara
RA   Yates, Andy
RA   Reinhold, William C.
RA   Weinstein, John N.
RA   Stratton, Michael Rudolf
RA   Futreal, P. Andrew
RA   Wooster, Richard
RT   "Mutation analysis of 24 known cancer genes in the NCI-60 cell line
RT   set.";
RL   Mol. Cancer Ther. 5:2606-2612(2006).
//
RX   PubMed=17332333; DOI=10.1158/0008-5472.CAN-06-3339;
RA   Okabe, Takafumi
RA   Okamoto, Isamu
RA   Tamura, Kenji
RA   Terashima, Masaaki
RA   Yoshida, Takeshi
RA   Satoh, Taroh
RA   Takada, Minoru
RA   Fukuoka, Masahiro
RA   Nakagawa, Kazuhiko
RT   "Differential constitutive activation of the epidermal growth factor
RT   receptor in non-small cell lung cancer cells bearing EGFR gene
RT   mutation and amplification.";
RL   Cancer Res. 67:2046-2053(2007).
//
RX   PubMed=17458138;
RA   Zhang, Hao
RA   Li, Na
RA   Chen, Yue
RA   Huang, Ling-Yun
RA   Wang, Yi-Ching
RA   Fang, Gang
RA   He, Da-Cheng
RA   Xiao, Xue-Yuan
RT   "Protein profile of human lung squamous carcinoma cell line
RT   NCI-H226.";
RL   Biomed. Environ. Sci. 20:24-32(2007).
//
RX   PubMed=18083107; DOI=10.1016/j.cell.2007.11.025;
RA   Rikova, Klarisa
RA   Guo, Ai-Lan
RA   Zeng, Qing-Fu
RA   Possemato, Anthony
RA   Yu, Jian
RA   Haack, Herbert
RA   Nardone, Julie
RA   Lee, Kimberly
RA   Reeves, Cynthia
RA   Li, Yu
RA   Hu, Ye-Rong
RA   Tan, Zhi-Ping
RA   Stokes, Matthew P.
RA   Sullivan, Laura
RA   Mitchell, Jeffrey
RA   Wetzel, Randy
RA   MacNeill, Joan
RA   Ren, Jian-Min
RA   Yuan, Jin
RA   Bakalarski, Corey E.
RA   Villen, Judit
RA   Kornhauser, Jon M.
RA   Smith, Bradley
RA   Li, Dai-Qiang
RA   Zhou, Xin-Min
RA   Gygi, Steven P.
RA   Gu, Ting-Lei
RA   Polakiewicz, Roberto D.
RA   Rush, John
RA   Comb, Michael J.
RT   "Global survey of phosphotyrosine signaling identifies oncogenic
RT   kinases in lung cancer.";
RL   Cell 131:1190-1203(2007).
//
RX   PubMed=19372543; DOI=10.1158/1535-7163.MCT-08-0921; PMCID=PMC4020356;
RA   Lorenzi, Philip L.
RA   Reinhold, William C.
RA   Varma, Sudhir
RA   Hutchinson, Amy A.
RA   Pommier, Yves
RA   Chanock, Stephen Jacob
RA   Weinstein, John N.
RT   "DNA fingerprinting of the NCI-60 cell line panel.";
RL   Mol. Cancer Ther. 8:713-724(2009).
//
RX   PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846;
RA   Blanco, Raquel
RA   Iwakawa, Reika
RA   Tang, Mo-Ying
RA   Kohno, Takashi
RA   Angulo, Barbara
RA   Pio, Ruben
RA   Montuenga, Luis M.
RA   Minna, John D.
RA   Yokota, Jun
RA   Sanchez-Cespedes, Montse
RT   "A gene-alteration profile of human lung cancer cell lines.";
RL   Hum. Mutat. 30:1199-1206(2009).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
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RA   Settleman, Jeffrey
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RT   polarity complex genes in diverse human cancers.";
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RX   PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x; PMCID=PMC11158680;
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RA   Kohno, Takashi
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RA   Yokota, Jun
RT   "Prevalence of human papillomavirus 16/18/33 infection and p53
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RA   Gottesman, Michael Marc
RT   "Redefining the relevance of established cancer cell lines to the
RT   study of mechanisms of clinical anti-cancer drug resistance.";
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RX   PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017;
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RA   Yamori, Takao
RT   "JFCR39, a panel of 39 human cancer cell lines, and its application in
RT   the discovery and development of anticancer drugs.";
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RX   PubMed=22347499; DOI=10.1371/journal.pone.0031628; PMCID=PMC3276511;
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RA   Kocher, Jean-Pierre A.
RA   Pommier, Yves
RA   Liu, Hong-Fang
RA   Reinhold, William C.
RT   "Mass homozygotes accumulation in the NCI-60 cancer cell lines as
RT   compared to HapMap trios, and relation to fragile site location.";
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RX   PubMed=22384151; DOI=10.1371/journal.pone.0032096; PMCID=PMC3285665;
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RA   Yoon, Chang No
RA   Chang, Young-Tae
RT   "Identification of cancer cell-line origins using fluorescence
RT   image-based phenomic screening.";
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RT   anticancer drug sensitivity.";
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RX   PubMed=22628656; DOI=10.1126/science.1218595; PMCID=PMC3526189;
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RT   cancer cell proliferation.";
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RT   lung cancer and novel therapeutic targets including PARP1.";
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RT   "The exomes of the NCI-60 panel: a genomic resource for cancer biology
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RT   "Global proteome analysis of the NCI-60 cell line panel.";
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RT   "Gene-expression data integration to squamous cell lung cancer
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RA   Sunshine, Margot
RA   Weinstein, John N.
RA   Reinhold, William C.
RT   "High resolution copy number variation data in the NCI-60 cancer cell
RT   lines from whole genome microarrays accessible through CellMiner.";
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RT   "A map of mobile DNA insertions in the NCI-60 human cancer cell
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//