ID   NCI-H2228
AC   CVCL_1543
SY   H2228; H-2228; NCIH2228
DR   BTO; BTO_0006023
DR   CLO; CLO_0008067
DR   EFO; EFO_0002284
DR   AddexBio; C0016017/4969
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-5935
DR   BCRJ; 0330
DR   BioSample; SAMN03473167
DR   BioSample; SAMN10987779
DR   cancercelllines; CVCL_1543
DR   CCRID; 3101HUMSCSP5001
DR   Cell_Model_Passport; SIDM00729
DR   ChEMBL-Cells; CHEMBL3308120
DR   ChEMBL-Targets; CHEMBL1075536
DR   CLS; 305125
DR   Cosmic; 687816
DR   Cosmic; 897513
DR   Cosmic; 903617
DR   Cosmic; 930491
DR   Cosmic; 1146905
DR   Cosmic; 1609517
DR   Cosmic; 1612226
DR   Cosmic; 1995564
DR   Cosmic-CLP; 687816
DR   DepMap; ACH-000447
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   GDSC; 687816
DR   GEO; GSM434317
DR   GEO; GSM513959
DR   GEO; GSM514344
DR   GEO; GSM794361
DR   GEO; GSM827512
DR   GEO; GSM887415
DR   GEO; GSM888494
DR   GEO; GSM1374727
DR   GEO; GSM1670226
DR   IARC_TP53; 27190
DR   IGRhCellID; NCIH2228
DR   LiGeA; CCLE_800
DR   LINCS_LDP; LCL-1652
DR   PharmacoDB; NCIH2228_1081_2019
DR   PRIDE; PXD011315
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1543
DR   PubChem_Cell_line; CVCL_1543
DR   Wikidata; Q54907944
RX   DOI=10.1101/2022.06.08.495301;
RX   PubMed=8626706;
RX   PubMed=8806092;
RX   PubMed=11030152;
RX   PubMed=18083107;
RX   PubMed=18594010;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=22334442;
RX   PubMed=22460905;
RX   PubMed=22961666;
RX   PubMed=23344087;
RX   PubMed=24675041;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=26589293;
RX   PubMed=27397505;
RX   PubMed=28196595;
RX   PubMed=29681454;
RX   PubMed=30710758;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31803961;
RX   PubMed=31900393;
RX   PubMed=31978347;
RX   PubMed=35839778;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: Caucasian.
CC   Doubling time: 77.2 hours (PubMed=31900393).
CC   HLA typing: A*02:01,03:01; B*07:02,38:01; C*07:02,12:03 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Gene fusion; HGNC; HGNC:427; ALK + HGNC; HGNC:1316; EML4; Name(s)=EML4-ALK; Note=E6A20 v3 fusion (PubMed=18594010; DOI=10.1101/2022.06.08.495301; DepMap=ACH-000447).
CC   Sequence variation: Gene fusion; HGNC; HGNC:427; ALK + HGNC; HGNC:9655; PTPN3; Name(s)=ALK-PTPN3 (PubMed=22334442).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln331Ter (c.991C>T); ClinVar=VCV000922893; Zygosity=Homozygous (Cosmic-CLP=687816; DepMap=ACH-000447).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Proteomics; Subcellular; Secretome.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0.1%; Native American=0.08%; East Asian, North=0.5%; East Asian, South=0.06%; South Asian=0.85%; European, North=65.31%; European, South=33.09% (PubMed=30894373).
CC   Misspelling: HC2228; Cosmic=1612226.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
ST   Source(s): AddexBio=C0016017/4969; ATCC=CRL-5935; Cosmic-CLP=687816; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11
ST   D16S539: 11,13
ST   D18S51: 16
ST   D19S433: 14,15
ST   D21S11: 28,30
ST   D2S1338: 17
ST   D3S1358: 16,18
ST   D5S818: 12
ST   D7S820: 11
ST   D8S1179: 13
ST   FGA: 21,22
ST   Penta D: 11,13
ST   Penta E: 11,16
ST   TH01: 7,8
ST   TPOX: 11
ST   vWA: 15,17
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 45
CH   CVCL_E3I6 ! HyCyte NCI-H2228-Luc
CH   CVCL_E6DB ! NCI-H2228-ARY
CH   CVCL_4V13 ! NCI-H2228-Luc
//
RX   PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254;
RA   Nusinow, David Paul
RA   Szpyt, John
RA   Ghandi, Mahmoud
RA   Rose, Christopher M.
RA   McDonald, E. Robert 3rd
RA   Kalocsay, Marian
RA   Jane-Valbuena, Judit
RA   Gelfand, Ellen T.
RA   Schweppe, Devin Karl
RA   Jedrychowski, Mark P.
RA   Golji, Javad
RA   Porter, Dale A.
RA   Rejtar, Tomas
RA   Wang, Y. Karen
RA   Kryukov, Gregory V.
RA   Stegmeier, Frank
RA   Erickson, Brian K.
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RA   Gygi, Steven P.
RT   "Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
RL   Cell 180:387-402.e16(2020).
//
RX   PubMed=18594010; DOI=10.1158/1078-0432.CCR-08-0168; PMCID=PMC3025451;
RA   Koivunen, Jussi Pekka
RA   Mermel, Craig H.
RA   Zejnullahu, Kreshnik
RA   Murphy, Carly
RA   Lifshits, Eugene
RA   Holmes, Alison J.
RA   Choi, Hwan Geun
RA   Kim, Jhingook
RA   Chiang, Derek Y.
RA   Thomas, Roman Kurt
RA   Lee, Jinseon
RA   Richards, William G.
RA   Sugarbaker, David John
RA   Ducko, Christopher Thomas
RA   Lindeman, Neal I.
RA   Marcoux, J. Paul 2nd
RA   Engelman, Jeffrey Adam
RA   Gray, Nathanael S.
RA   Lee, Charles
RA   Meyerson, Matthew Langer
RA   Janne, Pasi Antero
RT   "EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung
RT   cancer.";
RL   Clin. Cancer Res. 14:4275-4283(2008).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=23344087; DOI=10.1097/JTO.0b013e318283dcc0;
RA   Kim, Soyeon
RA   Kim, Tae Min
RA   Kim, Dong-Wan
RA   Go, Heounjeong
RA   Keam, Bhumsuk
RA   Lee, Se-Hoon
RA   Ku, Ja-Lok
RA   Chung, Doo Hyun
RA   Heo, Dae Seog
RT   "Heterogeneity of genetic changes associated with acquired crizotinib
RT   resistance in ALK-rearranged lung cancer.";
RL   J. Thorac. Oncol. 8:415-422(2013).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, Agda Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112; PMCID=PMC3567922;
RA   Byers, Lauren Averett
RA   Wang, Jing
RA   Nilsson, Monique B.
RA   Fujimoto, Junya
RA   Saintigny, Pierre
RA   Yordy, John Stuart
RA   Giri, Uma
RA   Peyton, Michael
RA   Fan, You-Hong
RA   Diao, Li-Xia
RA   Masrorpour, Fatemeh
RA   Shen, Li
RA   Liu, Wen-Bin
RA   Duchemann, Boris
RA   Tumula, Praveen
RA   Bhardwaj, Vikas
RA   Welsh, James
RA   Weber, Stephanie
RA   Glisson, Bonnie S.
RA   Kalhor, Neda
RA   Wistuba, Ignacio Ivan
RA   Girard, Luc
RA   Lippman, Scott M.
RA   Mills, Gordon B.
RA   Coombes, Kevin Robert
RA   Weinstein, John N.
RA   Minna, John D.
RA   Heymach, John Victor
RT   "Proteomic profiling identifies dysregulated pathways in small cell
RT   lung cancer and novel therapeutic targets including PARP1.";
RL   Cancer Discov. 2:798-811(2012).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084;
RA   Mulshine, James L.
RA   Ujhazy, Peter
RA   Antman, Melissa
RA   Burgess, Christine M.
RA   Kuzmin, Igor A.
RA   Bunn, Paul A. Jr.
RA   Johnson, Bruce E.
RA   Roth, Jack Alan
RA   Pass, Harvey I.
RA   Ross, Sheila M.
RA   Aldige, Carolyn R.
RA   Wistuba, Ignacio Ivan
RA   Minna, John D.
RT   "From clinical specimens to human cancer preclinical models -- a journey
RT   the NCI-cell line database-25 years later.";
RL   J. Cell. Biochem. 121:3986-3999(2020).
//
RX   PubMed=24675041; DOI=10.1158/2159-8290.CD-13-0846; PMCID=PMC4068971;
RA   Friboulet, Luc
RA   Li, Nan-Xin
RA   Katayama, Ryohei
RA   Lee, Christian C.
RA   Gainor, Justin Franklin
RA   Crystal, Adam S.
RA   Michellys, Pierre-Yves
RA   Awad, Mark M.
RA   Yanagitani, Noriko
RA   Kim, Sungjoon
RA   Pferdekamper, AnneMarie Culazzo
RA   Li, Jie
RA   Kasibhatla, Shailaja
RA   Sun, Frank
RA   Sun, Xiu-Ying
RA   Hua, Su
RA   McNamara, Peter
RA   Mahmood, Sidra
RA   Lockerman, Elizabeth L.
RA   Fujita, Naoya
RA   Nishio, Makoto
RA   Harris, Jennifer L.
RA   Shaw, Alice Tsang
RA   Engelman, Jeffrey Adam
RT   "The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small
RT   cell lung cancer.";
RL   Cancer Discov. 4:662-673(2014).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=8806092; DOI=10.1002/jcb.240630505;
RA   Phelps, Ruby M.
RA   Johnson, Bruce E.
RA   Ihde, Daniel Carlyle
RA   Gazdar, Adi F.
RA   Carbone, David P.
RA   McClintock, Patrick R.
RA   Linnoila, Ritva Ilona
RA   Matthews, Mary J.
RA   Bunn, Paul A. Jr.
RA   Carney, Desmond Niall
RA   Minna, John D.
RA   Mulshine, James L.
RT   "NCI-Navy Medical Oncology Branch cell line data base.";
RL   J. Cell. Biochem. Suppl. 24:32-91(1996).
//
RX   DOI=10.1101/2022.06.08.495301;
RA   Licciardello, Marco P.
RA   Zhang, Chi
RA   Le, Anh T.
RA   Doebele, Robert C.
RA   Clarke, Paul A.
RA   Workman, Paul
RT   "Loss of spindly sensitizes EML4-ALK v3 lung cancer cells to HSP90
RT   inhibitors.";
RL   bioRxiv 2022:06.08.495301-06.08.495301(2022).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina, Jordi Ginesta
RA   Caponigro, Giordano
RA   Stransky, Nicolas
RA   Venkatesan, Kavitha
RA   Margolin, Adam A.
RA   Kim, Sungjoon
RA   Wilson, Christopher J.
RA   Lehar, Joseph
RA   Kryukov, Gregory V.
RA   Sonkin, Dmitriy
RA   Reddy, Anupama
RA   Liu, Manway
RA   Murray, Lauren
RA   Berger, Michael F.
RA   Monahan, John E.
RA   Morais, Paula
RA   Meltzer, Jodi
RA   Korejwa, Adam
RA   Jane-Valbuena, Judit
RA   Mapa, Felipa A.
RA   Thibault, Joseph
RA   Bric-Furlong, Eva
RA   Raman, Pichai
RA   Shipway, Aaron
RA   Engels, Ingo H.
RA   Cheng, Jill
RA   Yu, Guo-Ying K.
RA   Yu, Jian-Jun
RA   Aspesi, Peter Jr.
RA   de Silva, Melanie
RA   Jagtap, Kalpana
RA   Jones, Michael D.
RA   Wang, Li
RA   Hatton, Charles
RA   Palescandolo, Emanuele
RA   Gupta, Supriya
RA   Mahan, Scott
RA   Sougnez, Carrie
RA   Onofrio, Robert C.
RA   Liefeld, Ted
RA   MacConaill, Laura Eleanor
RA   Winckler, Wendy
RA   Reich, Michael
RA   Li, Nan-Xin
RA   Mesirov, Jill P.
RA   Gabriel, Stacey B.
RA   Getz, Gad
RA   Ardlie, Kristin
RA   Chan, Vivien
RA   Myer, Vic E.
RA   Weber, Barbara L.
RA   Porter, Jeff
RA   Warmuth, Markus
RA   Finan, Peter
RA   Harris, Jennifer L.
RA   Meyerson, Matthew Langer
RA   Golub, Todd Robert
RA   Morrissey, Michael P.
RA   Sellers, William Raj
RA   Schlegel, Robert
RA   Garraway, Levi Alexander
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=30710758; DOI=10.1016/j.jprot.2019.01.018;
RA   Bottger, Franziska
RA   Schaaij-Visser, Tieneke B.M.
RA   de Reus, Inge
RA   Piersma, Sander R.
RA   Pham, Thang V.
RA   Nagel, Remco
RA   Brakenhoff, Ruud H.
RA   Thunnissen, Erik
RA   Smit, Egbert F.
RA   Jimenez, Connie R.
RT   "Proteome analysis of non-small cell lung cancer cell line secretomes
RT   and patient sputum reveals biofluid biomarker candidates for
RT   cisplatin response prediction.";
RL   J. Proteomics 196:106-119(2019).
//
RX   PubMed=22334442; DOI=10.1002/gcc.21945;
RA   Jung, Yeonjoo
RA   Kim, Pora
RA   Jung, Yeonhwa
RA   Keum, Juhee
RA   Kim, Soon-Nam
RA   Choi, Yong Soo
RA   Do, In-Gu
RA   Lee, Jinseon
RA   Choi, So-Jung
RA   Kim, Sujin
RA   Lee, Jong-Eun
RA   Kim, Jhingook
RA   Lee, Sanghyuk
RA   Kim, Jaesang
RT   "Discovery of ALK-PTPN3 gene fusion from human non-small cell lung
RT   carcinoma cell line using next generation RNA sequencing.";
RL   Genes Chromosomes Cancer 51:590-597(2012).
//
RX   PubMed=29681454; DOI=10.1016/j.cell.2018.03.028; PMCID=PMC5935540;
RA   McMillan, Elizabeth A.
RA   Ryu, Myung-Jeom
RA   Diep, Caroline H.
RA   Mendiratta, Saurabh
RA   Clemenceau, Jean Rene
RA   Vaden, Rachel M.
RA   Kim, Ju-Hwa
RA   Motoyaji, Takashi
RA   Covington, Kyle R.
RA   Peyton, Michael
RA   Huffman, Kenneth
RA   Wu, Xiao-Feng
RA   Girard, Luc
RA   Sung, Yeojin
RA   Chen, Pei-Hsaun
RA   Mallipeddi, Prema Latha
RA   Lee, Joo Young
RA   Hanson, Jordan
RA   Voruganti, Sukesh
RA   Yu, Yunku
RA   Park, Sunho
RA   Sudderth, Jessica
RA   DeSevo, Christopher
RA   Muzny, Donna M.
RA   Doddapaneni, HarshaVardhan
RA   Gazdar, Adi F.
RA   Gibbs, Richard Alexander
RA   Hwang, Tae Hyun
RA   Heymach, John Victor
RA   Wistuba, Ignacio Ivan
RA   Coombes, Kevin Robert
RA   Williams, Noelle S.
RA   Wheeler, David A.
RA   MacMillan, John B.
RA   DeBerardinis, Ralph J.
RA   Roth, Michael G.
RA   Posner, Bruce Arthur
RA   Minna, John D.
RA   Kim, Hyun Seok
RA   White, Michael A.
RT   "Chemistry-first approach for nomination of personalized treatment in
RT   lung cancer.";
RL   Cell 173:864-878.e29(2018).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//
RX   PubMed=8626706; DOI=10.1074/jbc.271.19.11477;
RA   Quinn, Kathryn A.
RA   Treston, Anthony M.
RA   Unsworth, Edward J.
RA   Miller, Mae-Jean
RA   Vos, Michele
RA   Grimley, Chris
RA   Battey, James
RA   Mulshine, James L.
RA   Cuttitta, Frank
RT   "Insulin-like growth factor expression in human cancer cell lines.";
RL   J. Biol. Chem. 271:11477-11483(1996).
//
RX   PubMed=11030152; DOI=10.1038/sj.onc.1203815;
RA   Modi, Sanjay
RA   Kubo, Akihito
RA   Oie, Herbert Kazuto
RA   Coxon, Amy B.
RA   Rehmatulla, Ahad
RA   Kaye, Frederic J.
RT   "Protein expression of the RB-related gene family and SV40 large T
RT   antigen in mesothelioma and lung cancer.";
RL   Oncogene 19:4632-4639(2000).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=31900393; DOI=10.1038/s41467-019-13771-5; PMCID=PMC6941996;
RA   Tsuji, Takahiro
RA   Ozasa, Hiroaki
RA   Aoki, Wataru
RA   Aburaya, Shunsuke
RA   Yamamoto Funazo, Tomoko
RA   Furugaki, Koh
RA   Yoshimura, Yasushi
RA   Yamazoe, Masatoshi
RA   Ajimizu, Hitomi
RA   Yasuda, Yuto
RA   Nomizo, Takashi
RA   Yoshida, Hironori
RA   Sakamori, Yuichi
RA   Wake, Hiroaki
RA   Ueda, Mitsuyoshi
RA   Kim, Young Hak
RA   Hirai, Toyohiro
RT   "YAP1 mediates survival of ALK-rearranged lung cancer cells treated
RT   with alectinib via pro-apoptotic protein regulation.";
RL   Nat. Commun. 11:74.1-74.16(2020).
//
RX   PubMed=18083107; DOI=10.1016/j.cell.2007.11.025;
RA   Rikova, Klarisa
RA   Guo, Ai-Lan
RA   Zeng, Qing-Fu
RA   Possemato, Anthony
RA   Yu, Jian
RA   Haack, Herbert
RA   Nardone, Julie
RA   Lee, Kimberly
RA   Reeves, Cynthia
RA   Li, Yu
RA   Hu, Ye-Rong
RA   Tan, Zhi-Ping
RA   Stokes, Matthew P.
RA   Sullivan, Laura
RA   Mitchell, Jeffrey
RA   Wetzel, Randy
RA   MacNeill, Joan
RA   Ren, Jian-Min
RA   Yuan, Jin
RA   Bakalarski, Corey E.
RA   Villen, Judit
RA   Kornhauser, Jon M.
RA   Smith, Bradley
RA   Li, Dai-Qiang
RA   Zhou, Xin-Min
RA   Gygi, Steven P.
RA   Gu, Ting-Lei
RA   Polakiewicz, Roberto D.
RA   Rush, John
RA   Comb, Michael J.
RT   "Global survey of phosphotyrosine signaling identifies oncogenic
RT   kinases in lung cancer.";
RL   Cell 131:1190-1203(2007).
//