ID NCI-H209 AC CVCL_1525 SY H209; H-209; NCIH209 DR BTO; BTO_0003020 DR CLO; CLO_0008049 DR EFO; EFO_0006671 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ATCC; HTB-172 DR BCRC; 60123 DR BioSample; SAMN03473244 DR BioSample; SAMN10988204 DR cancercelllines; CVCL_1525 DR CCRID; 1101HUM-PUMC000045 DR Cell_Model_Passport; SIDM00706 DR ChEMBL-Cells; CHEMBL3308293 DR ChEMBL-Targets; CHEMBL2366365 DR CLS; 300183 DR Cosmic; 688013 DR Cosmic; 755463 DR Cosmic; 801617 DR Cosmic; 808317 DR Cosmic; 808396 DR Cosmic; 844819 DR Cosmic; 850429 DR Cosmic; 876165 DR Cosmic; 877202 DR Cosmic; 897518 DR Cosmic; 1004691 DR Cosmic; 1021855 DR Cosmic; 1219100 DR Cosmic; 1239937 DR Cosmic; 1518090 DR Cosmic; 1891903 DR Cosmic; 2125243 DR Cosmic; 2239097 DR Cosmic; 2301573 DR Cosmic; 2668346 DR Cosmic; 2699652 DR Cosmic-CLP; 688013 DR DepMap; ACH-000290 DR DSMZ; ACC-499 DR DSMZ; ACC-900 DR DSMZCellDive; ACC-900 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 688013 DR GEO; GSM169438 DR GEO; GSM170735 DR GEO; GSM170736 DR GEO; GSM170737 DR GEO; GSM171856 DR GEO; GSM171857 DR GEO; GSM380511 DR GEO; GSM784248 DR GEO; GSM794276 DR GEO; GSM844636 DR GEO; GSM845543 DR GEO; GSM887403 DR GEO; GSM888482 DR GEO; GSM1374721 DR GEO; GSM1670214 DR GEO; GSM1887905 DR GEO; GSM1887988 DR IARC_TP53; 329 DR IGRhCellID; NCIH209 DR KCB; KCB 200816YJ DR KCLB; 30172 DR LiGeA; CCLE_619 DR LINCS_LDP; LCL-1847 DR PharmacoDB; NCIH209_1065_2019 DR PRIDE; PXD011896 DR PRIDE; PXD030304 DR Progenetix; CVCL_1525 DR PubChem_Cell_line; CVCL_1525 DR Wikidata; Q54907921 RX PubMed=1563005; RX PubMed=2985257; RX PubMed=2986243; RX PubMed=6148444; RX PubMed=6270685; RX PubMed=6272398; RX PubMed=6713399; RX PubMed=7736387; RX PubMed=8626706; RX PubMed=8806092; RX PubMed=8806103; RX PubMed=9559342; RX PubMed=9559344; RX PubMed=9815546; RX PubMed=10037197; RX PubMed=10536175; RX PubMed=10987304; RX PubMed=11005564; RX PubMed=11030152; RX PubMed=11314036; RX PubMed=14762065; RX PubMed=16157194; RX PubMed=17426248; RX PubMed=19472407; RX PubMed=20016488; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=20557307; RX PubMed=20624269; RX PubMed=22460905; RX PubMed=22961666; RX PubMed=23716474; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=26589293; RX PubMed=27247353; RX PubMed=27397505; RX PubMed=28766886; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31803961; RX PubMed=32586373; RX PubMed=34439128; RX PubMed=35839778; WW Info; Pawefish; -; https://www.cellosaurus.org/pawefish/LungCellLineDescriptions/NCI-H209.html CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Population: Caucasian. CC Doubling time: ~50-70 hours (DSMZ=ACC-900). CC HLA typing: A*34:02,34:02; B*07:04,14:01; C*03:07,08:02 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Cys706Phe (c.2117G>T); ClinVar=VCV000376330; Zygosity=Homozygous (ATCC=HTB-172; Cosmic-CLP=688013; DepMap=ACH-000290). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.673-2A>T (IVS6-2A>T); ClinVar=VCV000635388; Zygosity=Homozygous (PubMed=20557307; Cosmic-CLP=688013; DepMap=ACH-000290). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Genomics; Whole genome sequencing. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; miRNA profiling; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=1.88%; Native American=0%; East Asian, North=1.08%; East Asian, South=0%; South Asian=0.08%; European, North=65.94%; European, South=31.02% (PubMed=30894373). CC Discontinued: DSMZ; ACC-499; true. CC Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371. ST Source(s): ATCC=HTB-172; CCRID=1101HUM-PUMC000045; CLS=300183; Cosmic-CLP=688013; DSMZ=ACC-900; KCLB=30172; PubMed=25877200 ST Amelogenin: X (DSMZ=ACC-900) ST Amelogenin: X,Y (ATCC=HTB-172; CCRID=1101HUM-PUMC000045; CLS=300183; Cosmic-CLP=688013; KCLB=30172; PubMed=25877200) ST CSF1PO: 11 (ATCC=HTB-172; CCRID=1101HUM-PUMC000045; CLS=300183; Cosmic-CLP=688013; KCLB=30172; PubMed=25877200) ST CSF1PO: 11,12 (DSMZ=ACC-900) ST D13S317: 11 ST D16S539: 9,12 ST D18S51: 13 ST D19S433: 14.2,15 (ATCC=HTB-172; CCRID=1101HUM-PUMC000045) ST D19S433: 15 (DSMZ=ACC-900) ST D21S11: 32.2 ST D2S1338: 17,20 ST D3S1358: 18 (ATCC=HTB-172; CLS=300183; DSMZ=ACC-900; KCLB=30172; PubMed=25877200) ST D3S1358: 18,20 (CCRID=1101HUM-PUMC000045) ST D5S818: 12 ST D7S820: 9 ST D8S1179: 12,13 ST FGA: 20,24 ST Penta D: 11,12 ST Penta E: 11,12 (ATCC=HTB-172; CLS=300183; PubMed=25877200) ST Penta E: 12 (DSMZ=ACC-900) ST TH01: 7,9 ST TPOX: 8 ST vWA: 18,19 DI NCIt; C4917; Lung small cell carcinoma DI ORDO; Orphanet_70573; Small cell lung cancer OX NCBI_TaxID=9606; ! Homo sapiens (Human) OI CVCL_2649 ! NCI-BL209 SX Male AG 55Y CA Cancer cell line DT Created: 04-04-12; Last updated: 14-08-25; Version: 49 CH CVCL_9V41 ! H209/CP CH CVCL_9V42 ! H209/VP // RX PubMed=7736387; DOI=10.1002/1097-0142(19950515)75:10<2442::AID-CNCR2820751009>3.0.CO;2-Q; RA Campling, Barbara G. RA Sarda, Inder R. RA Baer, Kathy A. RA Pang, Stephen C. RA Baker, Heather M. RA Lofters, Wycliffe S. RA Flynn, T. Geoffrey RT "Secretion of atrial natriuretic peptide and vasopressin by small cell RT lung cancer."; RL Cancer 75:2442-2451(1995). // RX PubMed=9815546; RA Campling, Barbara G. RA Young, Leah C. RA Baer, Kathy A. RA Lam, Yuk-Miu RA Deeley, Roger G. RA Cole, Susan P.C. RA Gerlach, James H. RT "Expression of the MRP and MDR1 multidrug resistance genes in small RT cell lung cancer."; RL Clin. Cancer Res. 3:115-122(1997). // RX PubMed=6270685; DOI=10.1073/pnas.78.7.4591; PMCID=PMC319839; RA Cuttitta, Frank RA Rosen, Steven T. RA Gazdar, Adi F. RA Minna, John D. RT "Monoclonal antibodies that demonstrate specificity for several types RT of human lung cancer."; RL Proc. Natl. Acad. Sci. U.S.A. 78:4591-4595(1981). // RX PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x; PMCID=PMC11158680; RA Iwakawa, Reika RA Kohno, Takashi RA Enari, Masatoshi RA Kiyono, Tohru RA Yokota, Jun RT "Prevalence of human papillomavirus 16/18/33 infection and p53 RT mutation in lung adenocarcinoma."; RL Cancer Sci. 101:1891-1896(2010). // RX PubMed=2986243; DOI=10.1007/978-3-642-82372-5_4; RA Whang-Peng, Jacqueline RA Lee, Elaine C. RT "Cytogenetics of human small cell lung cancer."; RL Recent Results Cancer Res. 97:37-46(1985). // RX PubMed=20016488; DOI=10.1038/nature08629; PMCID=PMC2880489; RA Pleasance, Erin D. RA Stephens, Philip J. RA O'Meara, Sarah RA McBride, David J. RA Meynert, Alison RA Jones, David RA Lin, Meng-Lay RA Beare, David RA Lau, King Wai RA Greenman, Christopher D. RA Varela, Ignacio RA Nik-Zainal, Serena RA Davies, Helen R. RA Ordonez, Gonzalo R. RA Mudie, Laura J. RA Latimer, Calli RA Edkins, Sarah RA Stebbings, Lucy A. RA Chen, Lina RA Jia, Ming-Ming RA Leroy, Catherine RA Marshall, John RA Menzies, Andrew RA Butler, Adam P. RA Teague, Jon W. RA Mangion, Jonathan RA Sun, Yong-Ming A. RA McLaughlin, Stephen F. RA Peckham, Heather E. RA Tsung, Eric F. RA Costa, Gina L. RA Lee, Clarence C. RA Minna, John D. RA Gazdar, Adi F. RA Birney, Ewan RA Rhodes, Michael D. RA McKernan, Kevin J. RA Stratton, Michael Rudolf RA Futreal, P. Andrew RA Campbell, Peter J. RT "A small-cell lung cancer genome with complex signatures of tobacco RT exposure."; RL Nature 463:184-190(2010). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=32586373; DOI=10.1186/s13148-020-00876-8; PMCID=PMC7318526; RA Krushkal, Julia RA Silvers, Thomas E. RA Reinhold, William C. RA Sonkin, Dmitriy RA Vural, Suleyman RA Connelly, John RA Varma, Sudhir RA Meltzer, Paul S. RA Kunkel, Mark W. RA Rapisarda, Annamaria RA Evans, David RA Pommier, Yves RA Teicher, Beverly A. RT "Epigenome-wide DNA methylation analysis of small cell lung cancer RT cell lines suggests potential chemotherapy targets."; RL Clin. Epigenetics 12:93.1-93.28(2020). // RX PubMed=9559344; DOI=10.1002/(SICI)1098-2264(199804)21:4<326::AID-GCC6>3.0.CO;2-0; RA Mulligan, Lois M. RA Timmer, Tineke RA Ivanchuk, Stacey M. RA Campling, Barbara G. RA Young, Leah C. RA Rabbitts, Pamela Helen RA Sundaresan, Vasi RA Hofstra, Robert M.W. RA Eng, Charis RT "Investigation of the genes for RET and its ligand complex, GDNF/GFR RT alpha-I, in small cell lung carcinoma."; RL Genes Chromosomes Cancer 21:326-332(1998). // RX PubMed=11005564; DOI=10.1038/sj.neo.7900094; PMCID=PMC1550293; RA Kohno, Takashi RA Sato, Takako RA Takakura, Satoshi RA Takei, Kimiko RA Inoue, Kaoru RA Nishioka, Michiho RA Yokota, Jun RT "Mutation and expression of the DCC gene in human lung cancer."; RL Neoplasia 2:300-305(2000). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=17426248; DOI=10.1158/1541-7786.MCR-06-0367; RA Olejniczak, Edward T. RA Van Sant, Charles RA Anderson, Mark G. RA Wang, Gang RA Tahir, Stephen K. RA Sauter, Guido RA Lesniewski, Rick RA Semizarov, Dimitri RT "Integrative genomic analysis of small-cell lung carcinoma reveals RT correlates of sensitivity to bcl-2 antagonists and uncovers novel RT chromosomal gains."; RL Mol. Cancer Res. 5:331-339(2007). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). // RX PubMed=10987304; RA Girard, Luc RA Zochbauer-Muller, Sabine RA Virmani, Arvind K. RA Gazdar, Adi F. RA Minna, John D. RT "Genome-wide allelotyping of lung cancer identifies new regions of RT allelic loss, differences between small cell lung cancer and non-small RT cell lung cancer, and loci clustering."; RL Cancer Res. 60:4894-4906(2000). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=34439128; DOI=10.3390/cancers13163972; PMCID=PMC8391533; RA Fahrmann, Johannes Francois RA Katayama, Hiroyuki RA Irajizad, Ehsan RA Chakraborty, Ashish RA Kato, Taketo RA Mao, Xiang-Ying RA Park, Soyoung RA Murage, Eunice RA Rusling, Leona A. RA Yu, Chuan-Yih RA Cai, Yi-Ning RA Hsiao, Fu-Chung RA Dennison, Jennifer B. RA Tran, Hai T. RA Ostrin, Edwin Justin RA Wilson, David Oscar RA Yuan, Jian-Min RA Vykoukal, Jody V. RA Hanash, Samir M. RT "Plasma based protein signatures associated with small cell lung RT cancer."; RL Cancers (Basel) 13:3972.1-3972.17(2021). // RX PubMed=6272398; DOI=10.1126/science.6272398; RA Moody, Terry W. RA Pert, Candace Beebe RA Gazdar, Adi F. RA Carney, Desmond Niall RA Minna, John D. RT "High levels of intracellular bombesin characterize human small-cell RT lung carcinoma."; RL Science 214:1246-1248(1981). // RX PubMed=6148444; DOI=10.1093/jnci/73.4.801; RA Morstyn, George RA Russo, Angelo RA Carney, Desmond Niall RA Karawya, Essam RA Wilson, Samuel H. Jr. RA Mitchell, James B. RT "Heterogeneity in the radiation survival curves and biochemical RT properties of human lung cancer cell lines."; RL J. Natl. Cancer Inst. 73:801-807(1984). // RX PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846; RA Blanco, Raquel RA Iwakawa, Reika RA Tang, Mo-Ying RA Kohno, Takashi RA Angulo, Barbara RA Pio, Ruben RA Montuenga, Luis M. RA Minna, John D. RA Yokota, Jun RA Sanchez-Cespedes, Montse RT "A gene-alteration profile of human lung cancer cell lines."; RL Hum. Mutat. 30:1199-1206(2009). // RX PubMed=11030152; DOI=10.1038/sj.onc.1203815; RA Modi, Sanjay RA Kubo, Akihito RA Oie, Herbert Kazuto RA Coxon, Amy B. RA Rehmatulla, Ahad RA Kaye, Frederic J. RT "Protein expression of the RB-related gene family and SV40 large T RT antigen in mesothelioma and lung cancer."; RL Oncogene 19:4632-4639(2000). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=10536175; DOI=10.3892/ijo.15.5.927; RA Fujita, Takeshi RA Kiyama, Masaharu RA Tomizawa, Yoshio RA Kohno, Takashi RA Yokota, Jun RT "Comprehensive analysis of p53 gene mutation characteristics in lung RT carcinoma with special reference to histological subtypes."; RL Int. J. Oncol. 15:927-934(1999). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=27247353; DOI=10.1093/jnci/djw122; PMCID=PMC6279282; RA Polley, Eric C. RA Kunkel, Mark W. RA Evans, David RA Silvers, Thomas E. RA Delosh, Rene M. RA Laudeman, Julie RA Ogle, Chad RA Reinhart, Russell RA Selby, Michael RA Connelly, John RA Harris, Erik RA Fer, Nicole RA Sonkin, Dmitriy RA Kaur, Gurmeet RA Monks, Anne RA Malik, Shakun RA Morris, Joel RA Teicher, Beverly A. RT "Small cell lung cancer screen of oncology drugs, investigational RT agents, and gene and microRNA expression."; RL J. Natl. Cancer Inst. 108:djw122.1-djw122.11(2016). // RX PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112; PMCID=PMC3567922; RA Byers, Lauren Averett RA Wang, Jing RA Nilsson, Monique B. RA Fujimoto, Junya RA Saintigny, Pierre RA Yordy, John Stuart RA Giri, Uma RA Peyton, Michael RA Fan, You-Hong RA Diao, Li-Xia RA Masrorpour, Fatemeh RA Shen, Li RA Liu, Wen-Bin RA Duchemann, Boris RA Tumula, Praveen RA Bhardwaj, Vikas RA Welsh, James RA Weber, Stephanie RA Glisson, Bonnie S. RA Kalhor, Neda RA Wistuba, Ignacio Ivan RA Girard, Luc RA Lippman, Scott M. RA Mills, Gordon B. RA Coombes, Kevin Robert RA Weinstein, John N. RA Minna, John D. RA Heymach, John Victor RT "Proteomic profiling identifies dysregulated pathways in small cell RT lung cancer and novel therapeutic targets including PARP1."; RL Cancer Discov. 2:798-811(2012). // RX PubMed=9559342; DOI=10.1002/(SICI)1098-2264(199804)21:4<308::AID-GCC4>3.0.CO;2-2; RA Virmani, Arvind K. RA Fong, Kwun M. RA Kodagoda, Dulmini R. RA McIntire, Donald RA Hung, Jaclyn Y. RA Tonk, Vijay RA Minna, John D. RA Gazdar, Adi F. RT "Allelotyping demonstrates common and distinct patterns of chromosomal RT loss in human lung cancer types."; RL Genes Chromosomes Cancer 21:308-319(1998). // RX PubMed=23716474; DOI=10.1002/gcc.22076; PMCID=PMC3806277; RA Iwakawa, Reika RA Takenaka, Masataka RA Kohno, Takashi RA Shimada, Yoko RA Totoki, Yasushi RA Shibata, Tatsuhiro RA Tsuta, Koji RA Nishikawa, Ryo RA Noguchi, Masayuki RA Sato-Otsubo, Aiko RA Ogawa, Seishi RA Yokota, Jun RT "Genome-wide identification of genes with amplification and/or fusion RT in small cell lung cancer."; RL Genes Chromosomes Cancer 52:802-816(2013). // RX PubMed=28766886; DOI=10.1002/cam4.1131; PMCID=PMC5548882; RA Teicher, Beverly A. RA Silvers, Thomas E. RA Selby, Michael RA Delosh, Rene M. RA Laudeman, Julie RA Ogle, Chad RA Reinhart, Russell RA Parchment, Ralph E. RA Krushkal, Julia RA Sonkin, Dmitriy RA Rubinstein, Lawrence RA Morris, Joel RA Evans, David RT "Small cell lung carcinoma cell line screen of etoposide/carboplatin RT plus a third agent."; RL Cancer Med. 6:1952-1964(2017). // RX PubMed=20624269; DOI=10.1186/1756-9966-29-75; PMCID=PMC2907339; RA Du, Li-Qin RA Schageman, Jeoffrey J. RA Irnov, Irnov RA Girard, Luc RA Hammond, Scott M. RA Minna, John D. RA Gazdar, Adi F. RA Pertsemlidis, Alexander RT "MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells RT and suggests a possible pathological relationship between SCLCs and RT NSCLCs."; RL J. Exp. Clin. Cancer Res. 29:75.1-75.12(2010). // RX PubMed=1563005; RA Giaccone, Giuseppe RA Battey, James RA Gazdar, Adi F. RA Oie, Herbert Kazuto RA Draoui, Muriel RA Moody, Terry W. RT "Neuromedin B is present in lung cancer cell lines."; RL Cancer Res. 52:2732s-2736s(1992). // RX PubMed=16157194; DOI=10.1016/j.cancergencyto.2005.03.007; RA Grigorova, Mira RA Lyman, Rachel C. RA Caldas, Carlos RA Edwards, Paul A.W. RT "Chromosome abnormalities in 10 lung cancer cell lines of the NCI-H RT series analyzed with spectral karyotyping."; RL Cancer Genet. Cytogenet. 162:1-9(2005). // RX PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084; RA Mulshine, James L. RA Ujhazy, Peter RA Antman, Melissa RA Burgess, Christine M. RA Kuzmin, Igor A. RA Bunn, Paul A. Jr. RA Johnson, Bruce E. RA Roth, Jack Alan RA Pass, Harvey I. RA Ross, Sheila M. RA Aldige, Carolyn R. RA Wistuba, Ignacio Ivan RA Minna, John D. RT "From clinical specimens to human cancer preclinical models -- a journey RT the NCI-cell line database-25 years later."; RL J. Cell. Biochem. 121:3986-3999(2020). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=2985257; RA Carney, Desmond Niall RA Gazdar, Adi F. RA Bepler, Gerold RA Guccion, John G. RA Marangos, Paul J. RA Moody, Terry W. RA Zweig, Mark H. RA Minna, John D. RT "Establishment and identification of small cell lung cancer cell lines RT having classic and variant features."; RL Cancer Res. 45:2913-2923(1985). // RX PubMed=10037197; RA Tang, Xao X. RA Brodeur, Garrett M. RA Campling, Barbara G. RA Ikegaki, Naohiko RT "Coexpression of transcripts encoding EPHB receptor protein tyrosine RT kinases and their ephrin-B ligands in human small cell lung RT carcinoma."; RL Clin. Cancer Res. 5:455-460(1999). // RX PubMed=8806103; DOI=10.1002/jcb.240630516; RA Johnson, Bruce E. RA Russell, Edward RA Simmons, Alfreda M. RA Phelps, Ruby M. RA Steinberg, Seth M. RA Ihde, Daniel Carlyle RA Gazdar, Adi F. RT "MYC family DNA amplification in 126 tumor cell lines from patients RT with small cell lung cancer."; RL J. Cell. Biochem. Suppl. 24:210-217(1996). // RX PubMed=11314036; DOI=10.1038/sj.onc.1204211; RA Forgacs, Eva RA Wren, Jonathan D. RA Kamibayashi, Craig RA Kondo, Masashi RA Xu, Xie L. RA Markowitz, Sanford David RA Tomlinson, Gail E. RA Muller, Carolyn Y. RA Gazdar, Adi F. RA Garner, Harold Ray RA Minna, John D. RT "Searching for microsatellite mutations in coding regions in lung, RT breast, ovarian and colorectal cancers."; RL Oncogene 20:1005-1009(2001). // RX PubMed=6713399; RA Rosen, Steven T. RA Mulshine, James L. RA Cuttitta, Frank RA Fedorko, Joseph RA Carney, Desmond Niall RA Gazdar, Adi F. RA Minna, John D. RT "Analysis of human small cell lung cancer differentiation antigens RT using a panel of rat monoclonal antibodies."; RL Cancer Res. 44:2052-2061(1984). // RX PubMed=8626706; DOI=10.1074/jbc.271.19.11477; RA Quinn, Kathryn A. RA Treston, Anthony M. RA Unsworth, Edward J. RA Miller, Mae-Jean RA Vos, Michele RA Grimley, Chris RA Battey, James RA Mulshine, James L. RA Cuttitta, Frank RT "Insulin-like growth factor expression in human cancer cell lines."; RL J. Biol. Chem. 271:11477-11483(1996). // RX PubMed=14762065; DOI=10.1101/gr.2012304; PMCID=PMC327104; RA Bignell, Graham Robert RA Huang, Jing RA Greshock, Joel RA Watt, Stephen RA Butler, Adam P. RA West, Sofie RA Grigorova, Mira RA Jones, Keith W. RA Wei, Wen RA Stratton, Michael Rudolf RA Futreal, P. Andrew RA Weber, Bernard RA Shapero, Michael H. RA Wooster, Richard RT "High-resolution analysis of DNA copy number using oligonucleotide RT microarrays."; RL Genome Res. 14:287-295(2004). // RX PubMed=8806092; DOI=10.1002/jcb.240630505; RA Phelps, Ruby M. RA Johnson, Bruce E. RA Ihde, Daniel Carlyle RA Gazdar, Adi F. RA Carbone, David P. RA McClintock, Patrick R. RA Linnoila, Ritva Ilona RA Matthews, Mary J. RA Bunn, Paul A. Jr. RA Carney, Desmond Niall RA Minna, John D. RA Mulshine, James L. RT "NCI-Navy Medical Oncology Branch cell line data base."; RL J. Cell. Biochem. Suppl. 24:32-91(1996). //