ID SJNB-10 AC CVCL_1441 SY SJ-NB-10; SJ-NB10; SJNB10; NB10; NB10-DH; NB 90-9; NB90-9 DR BTO; BTO_0006052 DR CLO; CLO_0037083 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-3610 DR BioGRID_ORCS_Cell_line; 946 DR cancercelllines; CVCL_1441 DR Cell_Model_Passport; SIDM00259 DR ChEMBL-Cells; CHEMBL3308172 DR ChEMBL-Targets; CHEMBL2366243 DR Cosmic; 688069 DR Cosmic; 949171 DR Cosmic; 1109121 DR Cosmic; 1518076 DR Cosmic; 1526644 DR Cosmic; 1543770 DR Cosmic; 2239458 DR Cosmic-CLP; 949171 DR DepMap; ACH-002278 DR EGA; EGAS00001000978 DR GDSC; 949171 DR GEO; GSM692861 DR GEO; GSM1670146 DR IARC_TP53; 27181 DR LINCS_LDP; LCL-1989 DR PharmacoDB; NB10_985_2019 DR PRIDE; PXD030304 DR PubChem_Cell_line; CVCL_1441 DR Wikidata; Q54953554 RX DOI=10.1007/0-306-46872-7_2; RX PubMed=8490657; RX PubMed=8516298; RX PubMed=10935473; RX PubMed=20164919; RX PubMed=20655465; RX PubMed=22213050; RX PubMed=27397505; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=35839778; CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Population: Caucasian. CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Mutation; HGNC; HGNC:7765; NF1; Unexplicit; Partial deletion; Zygosity=Homozygous (PubMed=20655465). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.93%; Native American=0%; East Asian, North=0%; East Asian, South=0%; South Asian=1.43%; European, North=66.44%; European, South=31.2% (PubMed=30894373). ST Source(s): Cosmic-CLP=949171 ST Amelogenin: X,Y ST CSF1PO: 11,12 ST D13S317: 11 ST D16S539: 11,12 ST D5S818: 11 ST D7S820: 11,12 ST TH01: 6 ST TPOX: 8,10 ST vWA: 16,17 DI NCIt; C3270; Neuroblastoma DI ORDO; Orphanet_635; Neuroblastoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 2Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 37 // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX DOI=10.1007/0-306-46872-7_2; RA Thiele, Carol Jeanne RT "Neuroblastoma."; RL (In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999). // RX PubMed=10935473; DOI=10.1038/sj.neo.7900010; PMCID=PMC1716055; RA Kong, Xiao-Tang RA Valentine, Virginia A. RA Rowe, Susan T. RA Valentine, Marcus B. RA Ragsdale, Susan T. RA Jones, Bart G. RA Wilkinson, Deborah A. RA Brodeur, Garrett M. RA Cohn, Susan Lerner RA Look, Alfred Thomas RT "Lack of homozygously inactivated p73 in single-copy MYCN primary RT neuroblastomas and neuroblastoma cell lines."; RL Neoplasia 1:80-89(1999). // RX PubMed=20655465; DOI=10.1016/j.cell.2010.06.004; PMCID=PMC2913027; RA Holzel, Michael RA Huang, Si-Dong RA Koster, Jan RA Ora, Ingrid RA Lakeman, Arjan RA Caron, Huib Nicolaas RA Nijkamp, Wouter RA Xie, Jing RA Callens, Tom RA Asgharzadeh, Shahab RA Seeger, Robert C. RA Messiaen, Ludwine M. RA Versteeg, Rogier RA Bernards, Rene RT "NF1 is a tumor suppressor in neuroblastoma that determines retinoic RT acid response and disease outcome."; RL Cell 142:218-229(2010). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=22213050; DOI=10.1002/ijc.27415; PMCID=PMC3757132; RA Gawecka, Joanna E. RA Geerts, Dirk RA Koster, Jan RA Caliva, Maisel J. RA Sulzmaier, Florian J. RA Opoku-Ansah, John RA Wada, Randal K. RA Bachmann, Andre S. RA Ramos, Joe W. RT "PEA15 impairs cell migration and correlates with clinical features RT predicting good prognosis in neuroblastoma."; RL Int. J. Cancer 131:1556-1568(2012). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=8490657; DOI=10.1038/ng0193-62; RA The, Inge RA Murthy, Anita E. RA Hannigan, Gregory E. RA Jacoby, Lee B. RA Menon, Anil G. RA Gusella, James Francis RA Bernards, Andre RT "Neurofibromatosis type 1 gene mutations in neuroblastoma."; RL Nat. Genet. 3:62-66(1993). // RX PubMed=8516298; DOI=10.1073/pnas.90.12.5539; PMCID=PMC46756; RA Johnson, Maureen Riordan RA Look, Alfred Thomas RA DeClue, Jeffrey E. RA Valentine, Marcus B. RA Lowy, Douglas Ronald RT "Inactivation of the NF1 gene in human melanoma and neuroblastoma cell RT lines without impaired regulation of GTP.Ras."; RL Proc. Natl. Acad. Sci. U.S.A. 90:5539-5543(1993). //