ID   MUTZ-1
AC   CVCL_1431
SY   Mutz-1; MUTZ1; Menschliche Und Tierische Zellkulture-1
DR   CLO; CLO_0007901
DR   CLDB; cl3603
DR   ArrayExpress; E-MTAB-783
DR   BioSample; SAMN03151853
DR   cancercelllines; CVCL_1431
DR   Cell_Model_Passport; SIDM00656
DR   Cosmic; 908155
DR   Cosmic; 1995516
DR   Cosmic; 2491098
DR   DSMZ; ACC-13
DR   IARC_TP53; 21520
DR   Wikidata; Q54907097
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=9067587;
RX   PubMed=9168445;
RX   PubMed=19344951;
RX   PubMed=20164919;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a Namalwa derivative (PubMed=19344951). Originally thought to originate from a 5 year old girl with myelodysplastic disorder.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00376.
CC   Population: African; Kenyan.
CC   Virology: Contains 2 integrated copies of EBV genome on chromosome 1.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: DSMZ; ACC-13; true.
ST   Source(s): DSMZ
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11,12
ST   D16S539: 9
ST   D5S818: 12,13
ST   D7S820: 11
ST   TH01: 7,9.3
ST   TPOX: 6,11
ST   vWA: 14
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0067 ! Namalwa
SX   Female
AG   Children
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 29
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001).
//
RX   PubMed=9067587; DOI=10.1038/sj.leu.2400571;
RA   Uphoff C.C., MacLeod R.A.F., Denkmann S.A., Golub T.R., Borkhardt A.,
RA   Janssen J.W.G., Drexler H.G.;
RT   "Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in
RT   human early B-lineage leukemia cell lines.";
RL   Leukemia 11:441-447(1997).
//
RX   PubMed=9168445; DOI=10.3109/10428199709114174;
RA   Steube K.G., Gignac S.M., Hu Z.-B., Teepe D., Harms D., Kabisch H.,
RA   Gaedicke G., Hansen-Hagge T.E., MacLeod R.A.F., Quentmeier H.,
RA   Drexler H.G.;
RT   "In vitro culture studies of childhood myelodysplastic syndrome:
RT   establishment of the cell line MUTZ-1.";
RL   Leuk. Lymphoma 25:345-363(1997).
//
RX   PubMed=19344951; DOI=10.1016/j.leukres.2009.03.005;
RA   Drexler H.G., Dirks W.G., MacLeod R.A.F.;
RT   "Many are called MDS cell lines: one is chosen.";
RL   Leuk. Res. 33:1011-1016(2009).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//