ID   KYSE-170
AC   CVCL_1358
SY   KYSE 170; KYSE170; KYSE0170
DR   BioSample; SAMN03472369
DR   BioSample; SAMN03472501
DR   cancercelllines; CVCL_1358
DR   CGH-DB; 279-1
DR   CGH-DB; 9228-4
DR   Cosmic; 801331
DR   Cosmic; 918526
DR   Cosmic; 1581074
DR   Cosmic; 1876245
DR   Cosmic; 2698435
DR   GEO; GSM590304
DR   IARC_TP53; 7680
DR   JCRB; JCRB1082
DR   JCRB; NIHS0346
DR   Wikidata; Q54900806
RX   PubMed=1728357;
RX   PubMed=7913084;
RX   PubMed=8575860;
RX   PubMed=9033652;
RX   PubMed=11092977;
RX   PubMed=11520067;
RX   PubMed=15172977;
RX   PubMed=16045545;
RX   PubMed=16832412;
CC   Population: Japanese.
CC   Doubling time: 32.5 hours (PubMed=1728357).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly266Arg (c.796G>C); ClinVar=VCV000376605; Zygosity=Unspecified (PubMed=8575860).
CC   Omics: Transcriptomics; Microarray.
CC   Discontinued: JCRB; NIHS0346; true.
CC   Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
ST   Source(s): JCRB=JCRB1082
ST   Amelogenin: X
ST   CSF1PO: 10,12,13
ST   D13S317: 9
ST   D16S539: 9,10
ST   D5S818: 11,12
ST   D7S820: 11,12
ST   TH01: 7,9
ST   TPOX: 11
ST   vWA: 16,17
DI   NCIt; C4024; Esophageal squamous cell carcinoma
DI   ORDO; Orphanet_99977; Squamous cell carcinoma of the esophagus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 26
//
RX   PubMed=7913084; DOI=10.1002/ijc.2910580224;
RA   Kanda, Yuji
RA   Nishiyama, Yasuyuki
RA   Shimada, Yutaka
RA   Imamura, Masayuki
RA   Nomura, Hiroshi
RA   Hiai, Hiroshi
RA   Fukumoto, Manabu
RT   "Analysis of gene amplification and overexpression in human
RT   esophageal-carcinoma cell lines.";
RL   Int. J. Cancer 58:291-297(1994).
//
RX   PubMed=11520067; DOI=10.1006/bbrc.2001.5400;
RA   Kan, Takatsugu
RA   Shimada, Yutaka
RA   Sato, Fumiaki
RA   Maeda, Masato
RA   Kawabe, Atsushi
RA   Kaganoi, Jun-ichi
RA   Itami, Atsushi
RA   Yamasaki, Seiji
RA   Imamura, Masayuki
RT   "Gene expression profiling in human esophageal cancers using cDNA
RT   microarray.";
RL   Biochem. Biophys. Res. Commun. 286:792-801(2001).
//
RX   PubMed=11092977; DOI=10.1111/j.1349-7006.2000.tb00895.x; PMCID=PMC5926289;
RA   Pimkhaokham, Atiphan
RA   Shimada, Yutaka
RA   Fukuda, Yohji
RA   Kurihara, Naoki
RA   Imoto, Issei
RA   Yang, Zeng-Quan
RA   Imamura, Masayuki
RA   Nakamura, Yusuke
RA   Amagasa, Teruo
RA   Inazawa, Johji
RT   "Nonrandom chromosomal imbalances in esophageal squamous cell
RT   carcinoma cell lines: possible involvement of the ATF3 and CENPF genes
RT   in the 1q32 amplicon.";
RL   Jpn. J. Cancer Res. 91:1126-1133(2000).
//
RX   PubMed=9033652; DOI=10.1002/(SICI)1097-0215(19970207)70:4<437::AID-IJC11>3.0.CO;2-C;
RA   Tanaka, Hisashi
RA   Shimada, Yutaka
RA   Imamura, Masayuki
RA   Shibagaki, Ichio
RA   Ishizaki, Kanji
RT   "Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b)
RT   genes in 30 esophageal squamous-cell-carcinoma cell lines.";
RL   Int. J. Cancer 70:437-442(1997).
//
RX   PubMed=8575860; DOI=10.1002/(SICI)1097-0215(19960126)65:3<372::AID-IJC16>3.0.CO;2-C;
RA   Tanaka, Hisashi
RA   Shibagaki, Ichio
RA   Shimada, Yutaka
RA   Wagata, Takashi
RA   Imamura, Masayuki
RA   Ishizaki, Kanji
RT   "Characterization of p53 gene mutations in esophageal squamous cell
RT   carcinoma cell lines: increased frequency and different spectrum of
RT   mutations from primary tumors.";
RL   Int. J. Cancer 65:372-376(1996).
//
RX   PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172;
RA   Sonoda, Itaru
RA   Imoto, Issei
RA   Inoue, Jun
RA   Shibata, Tatsuhiro
RA   Shimada, Yutaka
RA   Chin, Koei
RA   Imamura, Masayuki
RA   Amagasa, Teruo
RA   Gray, Joe W.
RA   Hirohashi, Setsuo
RA   Inazawa, Johji
RT   "Frequent silencing of low density lipoprotein receptor-related
RT   protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in
RT   esophageal squamous cell carcinoma.";
RL   Cancer Res. 64:3741-3747(2004).
//
RX   PubMed=16045545; DOI=10.1111/j.0959-9673.2005.00431.x; PMCID=PMC2517430;
RA   Ban, Sadayuki
RA   Michikawa, Yuichi
RA   Ishikawa, Ken-ichi
RA   Sagara, Masashi
RA   Watanabe, Koji
RA   Shimada, Yutaka
RA   Inazawa, Johji
RA   Imai, Takashi
RT   "Radiation sensitivities of 31 human oesophageal squamous cell
RT   carcinoma cell lines.";
RL   Int. J. Exp. Pathol. 86:231-240(2005).
//
RX   PubMed=1728357; DOI=10.1002/1097-0142(19920115)69:2<277::AID-CNCR2820690202>3.0.CO;2-C;
RA   Shimada, Yutaka
RA   Imamura, Masayuki
RA   Wagata, Takashi
RA   Yamaguchi, Nozomi
RA   Tobe, Takayoshi
RT   "Characterization of 21 newly established esophageal cancer cell
RT   lines.";
RL   Cancer 69:277-284(1992).
//
RX   PubMed=16832412; DOI=10.1038/sj.bjc.6603255; PMCID=PMC2360647;
RA   Tsunoda, Shigeru
RA   Okumura, Tomoyuki
RA   Ito, Tetsuo
RA   Mori, Yukiko
RA   Soma, Toshiya
RA   Watanabe, Go
RA   Kaganoi, Jun-ichi
RA   Itami, Atsushi
RA   Sakai, Y.
RA   Shimada, Yutaka
RT   "Significance of nerve growth factor overexpression and its autocrine
RT   loop in oesophageal squamous cell carcinoma.";
RL   Br. J. Cancer 95:322-330(2006).
//