ID   KYSE-170
AC   CVCL_1358
SY   KYSE 170; KYSE170; KYSE0170
DR   BioSample; SAMN03472369
DR   BioSample; SAMN03472501
DR   cancercelllines; CVCL_1358
DR   CGH-DB; 279-1
DR   CGH-DB; 9228-4
DR   Cosmic; 801331
DR   Cosmic; 918526
DR   Cosmic; 1581074
DR   Cosmic; 1876245
DR   Cosmic; 2698435
DR   GEO; GSM590304
DR   IARC_TP53; 7680
DR   JCRB; JCRB1082
DR   JCRB; NIHS0346
DR   Wikidata; Q54900806
RX   PubMed=1728357;
RX   PubMed=7913084;
RX   PubMed=8575860;
RX   PubMed=9033652;
RX   PubMed=11092977;
RX   PubMed=11520067;
RX   PubMed=15172977;
RX   PubMed=16045545;
RX   PubMed=16832412;
CC   Population: Japanese.
CC   Doubling time: 32.5 hours (PubMed=1728357).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gly266Arg (c.796G>C); ClinVar=VCV000376605; Zygosity=Unspecified (PubMed=8575860).
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: JCRB; NIHS0346; true.
CC   Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
ST   Source(s): JCRB=JCRB1082
ST   Amelogenin: X
ST   CSF1PO: 10,12,13
ST   D13S317: 9
ST   D16S539: 9,10
ST   D5S818: 11,12
ST   D7S820: 11,12
ST   TH01: 7,9
ST   TPOX: 11
ST   vWA: 16,17
DI   NCIt; C4024; Esophageal squamous cell carcinoma
DI   ORDO; Orphanet_99977; Squamous cell carcinoma of the esophagus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 24
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RX   PubMed=1728357; DOI=10.1002/1097-0142(19920115)69:2<277::AID-CNCR2820690202>3.0.CO;2-C;
RA   Shimada Y., Imamura M., Wagata T., Yamaguchi N., Tobe T.;
RT   "Characterization of 21 newly established esophageal cancer cell
RT   lines.";
RL   Cancer 69:277-284(1992).
//
RX   PubMed=7913084; DOI=10.1002/ijc.2910580224;
RA   Kanda Y., Nishiyama Y., Shimada Y., Imamura M., Nomura H., Hiai H.,
RA   Fukumoto M.;
RT   "Analysis of gene amplification and overexpression in human
RT   esophageal-carcinoma cell lines.";
RL   Int. J. Cancer 58:291-297(1994).
//
RX   PubMed=8575860; DOI=10.1002/(SICI)1097-0215(19960126)65:3<372::AID-IJC16>3.0.CO;2-C;
RA   Tanaka H., Shibagaki I., Shimada Y., Wagata T., Imamura M.,
RA   Ishizaki K.;
RT   "Characterization of p53 gene mutations in esophageal squamous cell
RT   carcinoma cell lines: increased frequency and different spectrum of
RT   mutations from primary tumors.";
RL   Int. J. Cancer 65:372-376(1996).
//
RX   PubMed=9033652; DOI=10.1002/(SICI)1097-0215(19970207)70:4<437::AID-IJC11>3.0.CO;2-C;
RA   Tanaka H., Shimada Y., Imamura M., Shibagaki I., Ishizaki K.;
RT   "Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b)
RT   genes in 30 esophageal squamous-cell-carcinoma cell lines.";
RL   Int. J. Cancer 70:437-442(1997).
//
RX   PubMed=11092977; DOI=10.1111/j.1349-7006.2000.tb00895.x;
RA   Pimkhaokham A., Shimada Y., Fukuda Y., Kurihara N., Imoto I.,
RA   Yang Z.-Q., Imamura M., Nakamura Y., Amagasa T., Inazawa J.;
RT   "Nonrandom chromosomal imbalances in esophageal squamous cell
RT   carcinoma cell lines: possible involvement of the ATF3 and CENPF genes
RT   in the 1q32 amplicon.";
RL   Jpn. J. Cancer Res. 91:1126-1133(2000).
//
RX   PubMed=11520067; DOI=10.1006/bbrc.2001.5400;
RA   Kan T., Shimada Y., Sato F., Maeda M., Kawabe A., Kaganoi J.-i.,
RA   Itami A., Yamasaki S., Imamura M.;
RT   "Gene expression profiling in human esophageal cancers using cDNA
RT   microarray.";
RL   Biochem. Biophys. Res. Commun. 286:792-801(2001).
//
RX   PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172;
RA   Sonoda I., Imoto I., Inoue J., Shibata T., Shimada Y., Chin K.,
RA   Imamura M., Amagasa T., Gray J.W., Hirohashi S., Inazawa J.;
RT   "Frequent silencing of low density lipoprotein receptor-related
RT   protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in
RT   esophageal squamous cell carcinoma.";
RL   Cancer Res. 64:3741-3747(2004).
//
RX   PubMed=16045545; DOI=10.1111/j.0959-9673.2005.00431.x;
RA   Ban S., Michikawa Y., Ishikawa K.-i., Sagara M., Watanabe K.,
RA   Shimada Y., Inazawa J., Imai T.;
RT   "Radiation sensitivities of 31 human oesophageal squamous cell
RT   carcinoma cell lines.";
RL   Int. J. Exp. Pathol. 86:231-240(2005).
//
RX   PubMed=16832412; DOI=10.1038/sj.bjc.6603255;
RA   Tsunoda S., Okumura T., Ito T., Mori Y., Soma T., Watanabe G.,
RA   Kaganoi J.-i., Itami A., Sakai Y., Shimada Y.;
RT   "Significance of nerve growth factor overexpression and its autocrine
RT   loop in oesophageal squamous cell carcinoma.";
RL   Br. J. Cancer 95:322-330(2006).
//