ID HCC70 AC CVCL_1270 SY HCC-70; HCC 70; HCC0070; Hamon Cancer Center 70 DR BTO; BTO_0005963 DR CLO; CLO_0003658 DR EFO; EFO_0001181 DR ArrayExpress; E-MTAB-38 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR ArrayExpress; E-MTAB-3610 DR ArrayExpress; E-TABM-157 DR ArrayExpress; E-TABM-244 DR ATCC; CRL-2315 DR BCRJ; 0386 DR BioGRID_ORCS_Cell_line; 870 DR BioSample; SAMN03471365 DR BioSample; SAMN03471868 DR BioSample; SAMN10988137 DR cancercelllines; CVCL_1270 DR Cell_Model_Passport; SIDM00673 DR ChEMBL-Cells; CHEMBL3308739 DR ChEMBL-Targets; CHEMBL1075461 DR CLS; 305464 DR Cosmic; 687486 DR Cosmic; 904357 DR Cosmic; 907048 DR Cosmic; 1018474 DR Cosmic; 1047703 DR Cosmic; 1136352 DR Cosmic; 1287933 DR Cosmic; 1603213 DR Cosmic; 1935001 DR Cosmic; 1995435 DR Cosmic; 2164994 DR Cosmic-CLP; 907048 DR DepMap; ACH-000668 DR EGA; EGAS00001000610 DR EGA; EGAS00001000978 DR GDSC; 907048 DR GEO; GSM217580 DR GEO; GSM344372 DR GEO; GSM344422 DR GEO; GSM350500 DR GEO; GSM718288 DR GEO; GSM783941 DR GEO; GSM844014 DR GEO; GSM844015 DR GEO; GSM847391 DR GEO; GSM887058 DR GEO; GSM888128 DR GEO; GSM1053711 DR GEO; GSM1172876 DR GEO; GSM1172969 DR GEO; GSM1374512 DR GEO; GSM1401660 DR GEO; GSM1669862 DR IARC_TP53; 10269 DR IGRhCellID; HCC70 DR KCLB; 9S0070 DR LiGeA; CCLE_774 DR LINCS_HMS; 50219 DR LINCS_LDP; LCL-1335 DR PharmacoDB; HCC70_509_2019 DR PRIDE; PXD005295 DR PRIDE; PXD030304 DR Progenetix; CVCL_1270 DR PubChem_Cell_line; CVCL_1270 DR SLKBase; 3492 DR Wikidata; Q54881772 RX PubMed=9833771; RX PubMed=9865903; RX PubMed=11314036; RX PubMed=17157791; RX PubMed=18516279; RX PubMed=19582160; RX PubMed=20164919; RX PubMed=20215515; RX PubMed=20679594; RX PubMed=22460905; RX PubMed=23151021; RX PubMed=23601657; RX PubMed=24094812; RX PubMed=24176112; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=25960936; RX PubMed=25984343; RX PubMed=26589293; RX PubMed=27397505; RX PubMed=28196595; RX PubMed=28287265; RX PubMed=28889351; RX PubMed=29473000; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=35839778; WW Info; LINCS; ICBP43; https://lincs.hms.harvard.edu/resources/reagents/icbp43/ WW Info; MCLP; -; https://tcpaportal.org/mclp/ WW Info; Pawefish; -; https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/HCC70.html WW Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255 WW Provider; UT Southwestern; -; https://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf CC Group: Triple negative breast cancer (TNBC) cell line. CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Part of: ICBP43 breast cancer cell line panel. CC Part of: JWGray breast cancer cell line panel. CC Part of: MD Anderson Cell Lines Project. CC Population: African American. CC Doubling time: 93 hours (PubMed=25984343); 67.80 hours (JWGray panel). CC HLA typing: A*03:01,30:02; B*15:16,78:01; C*16:01,16:01; DQB1*05:01,05:01; DRB1*01:02,07:01 (PubMed=25960936). CC HLA typing: A*03:01,30:02; B*15:16,78:01; C*16:01,16:01 (PubMed=26589293). CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (PubMed=9865903; PubMed=28889351; ATCC=CRL-2315). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Phenotyping; shRNA library screening. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; PTM; Glycoproteome. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; miRNA profiling; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; CNV analysis. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=70.85%; Native American=0%; East Asian, North=5.47%; East Asian, South=0%; South Asian=0%; European, North=3.61%; European, South=20.07% (PubMed=30894373). CC Miscellaneous: Direct author submission of STR profile from Girard, Luc & Gazdar, Adi F. CC Derived from site: In situ; Breast; UBERON=UBERON_0000310. CC Cell type: Epithelial cell of mammary gland; CL=CL_0002327. ST Source(s): ATCC=CRL-2315; Cosmic-CLP=907048; Direct_author_submission; KCLB=9S0070; PubMed=20679594; PubMed=25877200; PubMed=28889351; Technion Genomics Center ST Amelogenin: X ST CSF1PO: 10 (KCLB=9S0070) ST CSF1PO: 10,14 (ATCC=CRL-2315; Cosmic-CLP=907048; Direct_author_submission; PubMed=20679594; PubMed=25877200; PubMed=28889351; Technion Genomics Center) ST D10S1248: 13 ST D12S391: 15,19 ST D13S317: 12 ST D16S539: 9,13 (ATCC=CRL-2315; Cosmic-CLP=907048; Direct_author_submission; PubMed=28889351; Technion Genomics Center) ST D16S539: 13 (PubMed=20679594; PubMed=25877200) ST D18S51: 13,16 ST D19S433: 12.2,15.2 ST D1S1656: 14 ST D21S11: 30 ST D22S1045: 14 ST D2S1338: 23,25 (PubMed=25877200; Technion Genomics Center) ST D2S1338: 25 (ATCC=CRL-2315; Direct_author_submission) ST D2S441: 11 ST D3S1358: 16 (KCLB=9S0070) ST D3S1358: 16,17 (ATCC=CRL-2315; Direct_author_submission; PubMed=25877200; Technion Genomics Center) ST D5S818: 12,13 (ATCC=CRL-2315; Cosmic-CLP=907048; Direct_author_submission; KCLB=9S0070; PubMed=20679594; PubMed=28889351; Technion Genomics Center) ST D5S818: 13 (PubMed=25877200) ST D7S820: 10,11 ST D8S1179: 13 ST FGA: 19.2,24 (ATCC=CRL-2315; Direct_author_submission; PubMed=25877200; Technion Genomics Center) ST FGA: 24 (KCLB=9S0070) ST Penta D: 10 ST Penta E: 9,16 ST TH01: 9 ST TPOX: 9,10 (Direct_author_submission; PubMed=20679594; PubMed=25877200; Technion Genomics Center) ST TPOX: 10 (ATCC=CRL-2315; Cosmic-CLP=907048; KCLB=9S0070; PubMed=28889351) ST vWA: 13,15 DI NCIt; C4017; Breast ductal carcinoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 49Y CA Cancer cell line DT Created: 04-04-12; Last updated: 14-08-25; Version: 47 CH CVCL_C9CI ! HCC70/Cas9-hyg // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590; RA Daemen, Anneleen RA Griffith, Obi L. RA Heiser, Laura M. RA Wang, Nicholas J. RA Enache, Oana M. RA Sanborn, Zachary J. RA Pepin, Francois RA Durinck, Steffen RA Korkola, James E. RA Griffith, Malachi RA Hur, Joe S. RA Huh, Nam RA Chung, Jongsuk RA Cope, Leslie RA Fackler, Mary Jo RA Umbricht, Christopher Benedict RA Sukumar, Saraswati RA Seth, Pankaj RA Sukhatme, Vikas P. RA Jakkula, Lakshmi R. RA Lu, Yi-Ling RA Mills, Gordon B. RA Cho, Raymond J. RA Collisson, Eric A. RA van 't Veer, Laura J. RA Spellman, Paul T. RA Gray, Joe W. RT "Modeling precision treatment of breast cancer."; RL Genome Biol. 14:R110.1-R110.14(2013). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=23151021; DOI=10.1186/1471-2164-13-619; PMCID=PMC3546428; RA Grigoriadis, Anita RA Mackay, Alan RA Noel, Elodie RA Wu, Pei-Jun RA Natrajan, Rachael RA Frankum, Jessica RA Reis-Filho, Jorge Sergio RA Tutt, Andrew N.J. RT "Molecular characterisation of cell line models for triple-negative RT breast cancers."; RL BMC Genomics 13:619.1-619.14(2012). // RX PubMed=28889351; DOI=10.1007/s10549-017-4496-x; RA Saunus, Jodi M. RA Smart, Chanel E. RA Kutasovic, Jamie R. RA Johnston, Rebecca L. RA Kalita-de Croft, Priyakshi RA Miranda, Mariska RA Rozali, Esdy N. RA Vargas, Ana Cristina RA Reid, Lynne E. RA Lorsy, Eva RA Cocciardi, Sibylle RA Seidens, Tatjana RA McCart Reed, Amy Ellen RA Dalley, Andrew J. RA Wockner, Leesa F. RA Johnson, Julie RA Sarkar, Debina RA Askarian-Amiri, Marjan E. RA Simpson, Peter T. RA Khanna, Kum Kum RA Chenevix-Trench, Georgia RA Al-Ejeh, Fares RA Lakhani, Sunil R. RT "Multidimensional phenotyping of breast cancer cell lines to guide RT preclinical research."; RL Breast Cancer Res. Treat. 167:289-301(2018). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=11314036; DOI=10.1038/sj.onc.1204211; RA Forgacs, Eva RA Wren, Jonathan D. RA Kamibayashi, Craig RA Kondo, Masashi RA Xu, Xie L. RA Markowitz, Sanford David RA Tomlinson, Gail E. RA Muller, Carolyn Y. RA Gazdar, Adi F. RA Garner, Harold Ray RA Minna, John D. RT "Searching for microsatellite mutations in coding regions in lung, RT breast, ovarian and colorectal cancers."; RL Oncogene 20:1005-1009(2001). // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=9833771; DOI=10.1002/(SICI)1097-0215(19981209)78:6<766::AID-IJC15>3.0.CO;2-L; RA Gazdar, Adi F. RA Kurvari, Venkatesh RA Virmani, Arvind K. RA Gollahon, Lauren S. RA Sakaguchi, Masahiro RA Westerfield, Max RA Kodagoda, Dulmini R. RA Stasny, Victor RA Cunningham, H. Thomas RA Wistuba, Ignacio Ivan RA Tomlinson, Gail E. RA Tonk, Vijay RA Ashfaq, Raheela RA Leitch, A. Marilyn RA Minna, John D. RA Shay, Jerry W. RT "Characterization of paired tumor and non-tumor cell lines established RT from patients with breast cancer."; RL Int. J. Cancer 78:766-774(1998). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=28287265; DOI=10.1021/acs.jproteome.6b00470; PMCID=PMC5557415; RA Yen, Ten-Yang RA Bowen, Spencer RA Yen, Roger RA Piryatinska, Alexandra RA Macher, Bruce A. RA Timpe, Leslie C. RT "Glycoproteins in claudin-low breast cancer cell lines have a unique RT expression profile."; RL J. Proteome Res. 16:1391-1400(2017). // RX PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310; RA Timmerman, Luika A. RA Holton, Thomas RA Yuneva, Mariia RA Louie, Raymond J. RA Padro, Merce RA Daemen, Anneleen RA Hu, Min RA Chan, Denise A. RA Ethier, Stephen P. RA van 't Veer, Laura J. RA Polyak, Kornelia RA McCormick, Frank RA Gray, Joe W. RT "Glutamine sensitivity analysis identifies the xCT antiporter as a RT common triple-negative breast tumor therapeutic target."; RL Cancer Cell 24:450-465(2013). // RX PubMed=20679594; DOI=10.1093/jnci/djq279; PMCID=PMC2935474; RA Gazdar, Adi F. RA Girard, Luc RA Lockwood, William W. RA Lam, Wan L. RA Minna, John D. RT "Lung cancer cell lines as tools for biomedical discovery and RT research."; RL J. Natl. Cancer Inst. 102:1310-1321(2010). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004; PMCID=PMC2391005; RA Kenny, Paraic A. RA Lee, Genee Y. RA Myers, Connie A. RA Neve, Richard M. RA Semeiks, Jeremy R. RA Spellman, Paul T. RA Lorenz, Kristina RA Lee, Eva H. RA Barcellos-Hoff, Mary Helen RA Petersen, Ole William RA Gray, Joe W. RA Bissell, Mina J. RT "The morphologies of breast cancer cell lines in three-dimensional RT assays correlate with their profiles of gene expression."; RL Mol. Oncol. 1:84-96(2007). // RX PubMed=9865903; RA Wistuba, Ignacio Ivan RA Behrens, Carmen RA Milchgrub, Sara RA Syed, Salahuddin RA Ahmadian, Mohsen RA Virmani, Arvind K. RA Kurvari, Venkatesh RA Cunningham, Thomas H. RA Ashfaq, Raheela RA Minna, John D. RA Gazdar, Adi F. RT "Comparison of features of human breast cancer cell lines and their RT corresponding tumors."; RL Clin. Cancer Res. 4:2931-2938(1998). // RX PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521; RA Neve, Richard M. RA Chin, Koei RA Fridlyand, Jane RA Yeh, Jennifer RA Baehner, Frederick L. RA Fevr, Tea RA Clark, Laura RA Bayani, Nora RA Coppe, Jean-Philippe RA Tong, Frances RA Speed, Terry RA Spellman, Paul T. RA DeVries, Sandy RA Lapuk, Anna RA Wang, Nick J. RA Kuo, Wen-Lin RA Stilwell, Jackie L. RA Pinkel, Daniel RA Albertson, Donna G. RA Waldman, Frederic M. RA McCormick, Frank RA Dickson, Robert Brent RA Johnson, Michael D. RA Lippman, Marc E. RA Ethier, Stephen P. RA Gazdar, Adi F. RA Gray, Joe W. RT "A collection of breast cancer cell lines for the study of RT functionally distinct cancer subtypes."; RL Cancer Cell 10:515-527(2006). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). // RX PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652; RA Cowley, Glenn S. RA Weir, Barbara A. RA Vazquez, Francisca RA Tamayo, Pablo RA Scott, Justine A. RA Rusin, Scott RA East-Seletsky, Alexandra RA Ali, Levi D. RA Gerath, William F.J. RA Pantel, Sarah E. RA Lizotte, Patrick Hall RA Jiang, Guo-Zhi RA Hsiao, Jessica RA Tsherniak, Aviad RA Dwinell, Elizabeth RA Aoyama, Simon RA Okamoto, Michael RA Harrington, William RA Gelfand, Ellen T. RA Green, Thomas M. RA Tomko, Mark J. RA Gopal, Shuba RA Wong, Terence C. RA Li, Hu-Bo RA Howell, Sara RA Stransky, Nicolas RA Liefeld, Ted RA Jang, Dongkeun RA Bistline, Jonathan RA Meyers, Barbara Hill RA Armstrong, Scott Allen RA Anderson, Kenneth Carl RA Stegmaier, Kimberly RA Reich, Michael RA Pellman, David RA Boehm, Jesse S. RA Mesirov, Jill P. RA Golub, Todd Robert RA Root, David E. RA Hahn, William Chun RT "Parallel genome-scale loss of function screens in 216 cancer cell RT lines for the identification of context-specific genetic RT dependencies."; RL Sci. Data 1:140035.1-140035.12(2014). // RX PubMed=29473000; DOI=10.7717/peerj.4340; PMCID=PMC5817938; RA Jogalekar, Manasi P. RA Serrano, Elba E. RT "Morphometric analysis of a triple negative breast cancer cell line in RT hydrogel and monolayer culture environments."; RL PeerJ 6:e4340.1-e4340.20(2018). // RX PubMed=23601657; DOI=10.1186/bcr3415; PMCID=PMC3672661; RA Riaz, Muhammad RA van Jaarsveld, Marijn T.M. RA Hollestelle, Antoinette RA Prager-van der Smissen, Wendy J.C. RA Heine, Anouk A.J. RA Boersma, Antonius W.M. RA Liu, Jing-Jing RA Helmijr, Jean C.A. RA Ozturk, Bahar RA Smid, Marcel RA Wiemer, Erik A.C. RA Foekens, John A. RA Martens, John W.M. RT "miRNA expression profiling of 51 human breast cancer cell lines RT reveals subtype and driver mutation-specific miRNAs."; RL Breast Cancer Res. 15:R33.1-R33.17(2013). // RX PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084; RA Kao, Jessica RA Salari, Keyan RA Bocanegra, Melanie RA Choi, Yoon-La RA Girard, Luc RA Gandhi, Jeet RA Kwei, Kevin A. RA Hernandez-Boussard, Tina RA Wang, Pei RA Gazdar, Adi F. RA Minna, John D. RA Pollack, Jonathan R. RT "Molecular profiling of breast cancer cell lines defines relevant RT tumor models and provides a resource for cancer gene discovery."; RL PLoS ONE 4:e6146.1-e6146.16(2009). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981; RA Boegel, Sebastian RA Lower, Martin RA Bukur, Thomas RA Sahin, Ugur RA Castle, John C. RT "A catalog of HLA type, HLA expression, and neo-epitope candidates in RT human cancer cell lines."; RL OncoImmunology 3:e954893.1-e954893.12(2014). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662; RA Rothenberg, S. Michael RA Mohapatra, Gayatry RA Rivera, Miguel N. RA Winokur, Daniel RA Greninger, Patricia RA Nitta, Mai RA Sadow, Peter M. RA Sooriyakumar, Gaya RA Brannigan, Brian W. RA Ulman, Matthew J. RA Perera, Rushika M. RA Wang, Rui RA Tam, Angela RA Ma, Xiao-Jun RA Erlander, Mark RA Sgroi, Dennis C. RA Rocco, James W. RA Lingen, Mark W. RA Cohen, Ezra E.W. RA Louis, David Neil RA Settleman, Jeffrey RA Haber, Daniel Arie RT "A genome-wide screen for microdeletions reveals disruption of RT polarity complex genes in diverse human cancers."; RL Cancer Res. 70:2158-2164(2010). //