ID   GOTO
AC   CVCL_1234
DR   BTO; BTO_0002253
DR   CLO; CLO_0037078
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   BioSample; SAMN03471632
DR   cancercelllines; CVCL_1234
DR   Cell_Model_Passport; SIDM00544
DR   CGH-DB; 79-1
DR   CGH-DB; 9101-4
DR   ChEMBL-Cells; CHEMBL3308168
DR   ChEMBL-Targets; CHEMBL2366179
DR   Cosmic; 801735
DR   Cosmic; 906875
DR   Cosmic; 920255
DR   Cosmic; 947701
DR   Cosmic; 1037351
DR   Cosmic; 1099148
DR   Cosmic; 1153780
DR   Cosmic; 2131591
DR   Cosmic-CLP; 906875
DR   DepMap; ACH-001716
DR   EGA; EGAS00001000978
DR   GDSC; 906875
DR   GEO; GSM313801
DR   GEO; GSM333796
DR   GEO; GSM827274
DR   GEO; GSM1669813
DR   IARC_TP53; 21052
DR   JCRB; JCRB0612
DR   LINCS_LDP; LCL-1974
DR   PharmacoDB; GOTO_409_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1234
DR   PubChem_Cell_line; CVCL_1234
DR   Wikidata; Q54871616
RX   DOI=10.1016/B978-0-12-008304-6.50015-4;
RX   DOI=10.1016/B978-0-12-333530-2.50006-X;
RX   PubMed=201151;
RX   PubMed=470188;
RX   PubMed=9290701;
RX   PubMed=12702577;
RX   PubMed=18082704;
RX   PubMed=18923524;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=27397505;
RX   PubMed=30894373;
RX   PubMed=35839778;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/g/cell-lines-detail-564.html
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Population: Japanese.
CC   Doubling time: ~48 hours (PubMed=470188).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (Cosmic-CLP=906875; DepMap=ACH-001716).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=74.22%; East Asian, South=25.78%; South Asian=0%; European, North=0%; European, South=0% (PubMed=30894373).
CC   Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
ST   Source(s): Cosmic-CLP=906875; DepMap=ACH-001716; JCRB=JCRB0612
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 15
ST   D16S539: 11,13
ST   D18S51: 14,15
ST   D21S11: 31,32,33
ST   D3S1358: 16,17
ST   D5S818: 11,12
ST   D7S820: 8,11
ST   D8S1179: 11,14
ST   FGA: 22
ST   Penta D: 9
ST   Penta E: 5,16
ST   TH01: 9
ST   TPOX: 11
ST   vWA: 17,18,19 (DepMap=ACH-001716)
ST   vWA: 17,19 (Cosmic-CLP=906875)
ST   vWA: 18,19 (JCRB=JCRB0612)
DI   NCIt; C4827; Adrenal gland neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1Y1M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 41
CH   CVCL_2911 ! GOTO.P3
//
RX   PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D;
RA   Jia, Li-Qun
RA   Osada, Motonobu
RA   Ishioka, Chikashi
RA   Gamo, Makio
RA   Ikawa, Shuntaro
RA   Suzuki, Takao
RA   Shimodaira, Hideki
RA   Niitani, Tomohito
RA   Kudo, Toshio
RA   Akiyama, Mitoshi
RA   Kimura, Narimiti
RA   Matsuo, Mitsuyoshi
RA   Mizusawa, Hiroshi
RA   Tanaka, Noriho
RA   Koyama, Hideki
RA   Namba, Masayoshi
RA   Kanamaru, Ryunosuke
RA   Kuroki, Toshio
RT   "Screening the p53 status of human cell lines using a yeast functional
RT   assay.";
RL   Mol. Carcinog. 19:243-253(1997).
//
RX   DOI=10.1016/B978-0-12-008304-6.50015-4;
RA   Biedler, June Lee
RA   Meyers, Marian B.
RA   Spengler, Barbara A.
RT   "Homogeneously staining regions and double minute chromosomes,
RT   prevalent cytogenetic abnormalities of human neuroblastoma cells.";
RL   (In book chapter) Advances in cellular neurobiology, Vol. 4; Fedoroff, Sergey & Hertz, Leif (eds.); pp.267-307; Academic Press; New York; USA (1983).
//
RX   PubMed=18923524; DOI=10.1038/nature07399;
RA   Chen, Yu-Yan
RA   Takita, Junko
RA   Choi, Young Lim
RA   Kato, Motohiro
RA   Ohira, Miki
RA   Sanada, Masashi
RA   Wang, Li-Li
RA   Soda, Manabu
RA   Kikuchi, Akira
RA   Igarashi, Takashi
RA   Nakagawara, Akira
RA   Hayashi, Yasuhide
RA   Mano, Hiroyuki
RA   Ogawa, Seishi
RT   "Oncogenic mutations of ALK kinase in neuroblastoma.";
RL   Nature 455:971-974(2008).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//
RX   DOI=10.1016/B978-0-12-333530-2.50006-X;
RA   Israel, Mark A.
RA   Thiele, Carol Jeanne
RT   "Tumor cell lines of the peripheral nervous system.";
RL   (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.43-78; Academic Press; New York; USA (1994).
//
RX   PubMed=18082704; DOI=10.1016/j.jpedsurg.2007.08.026;
RA   Komuro, Hiroaki
RA   Saihara, Ryoko
RA   Shinya, Miki
RA   Takita, Junko
RA   Kaneko, Setsuko
RA   Kaneko, Michio
RA   Hayashi, Yasuhide
RT   "Identification of side population cells (stem-like cell population)
RT   in pediatric solid tumor cell lines.";
RL   J. Pediatr. Surg. 42:2040-2045(2007).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469;
RA   Iorio, Francesco
RA   Knijnenburg, Theo A.
RA   Vis, Daniel J.
RA   Bignell, Graham Robert
RA   Menden, Michael Patrick
RA   Schubert, Michael
RA   Aben, Nanne
RA   Goncalves, Emanuel
RA   Barthorpe, Syd
RA   Lightfoot, Howard
RA   Cokelaer, Thomas
RA   Greninger, Patricia
RA   van Dyk, Ewald
RA   Chang, Han
RA   de Silva, Heshani
RA   Heyn, Holger
RA   Deng, Xian-Ming
RA   Egan, Regina K.
RA   Liu, Qing-Song
RA   Mironenko, Tatiana
RA   Mitropoulos, Xeni
RA   Richardson, Laura
RA   Wang, Jin-Hua
RA   Zhang, Ting-Hu
RA   Moran, Sebastian
RA   Sayols, Sergi
RA   Soleimani, Maryam
RA   Tamborero, David
RA   Lopez-Bigas, Nuria
RA   Ross-Macdonald, Petra
RA   Esteller, Manel
RA   Gray, Nathanael S.
RA   Haber, Daniel Arie
RA   Stratton, Michael Rudolf
RA   Benes, Cyril Henri
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=470188;
RA   Sekiguchi, Morimasa
RA   Oota, Taeko
RA   Sakakibara, Kooko
RA   Inui, Naomichi
RA   Fujii, Genshichiro
RT   "Establishment and characterization of a human neuroblastoma cell line
RT   in tissue culture.";
RL   Jpn. J. Exp. Med. 49:67-83(1979).
//
RX   PubMed=201151; DOI=10.1111/j.1440-1827.1977.tb00186.x;
RA   Ishikawa, Shinobu
RT   "Differentiation of human neuroblastoma cells in vitro -- morphological
RT   changes induced by dibutyrl cyclic AMP.";
RL   Acta Pathol. Jpn. 27:697-711(1977).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
RA   Chen, Zhi-Hua
RA   Monteiro, Alvaro N.A.
RA   Teer, Jamie K.
RA   Eschrich, Steven A.
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell, Graham Robert
RA   Greenman, Christopher D.
RA   Davies, Helen R.
RA   Butler, Adam P.
RA   Edkins, Sarah
RA   Andrews, Jenny M.
RA   Buck, Gemma
RA   Chen, Lina
RA   Beare, David
RA   Latimer, Calli
RA   Widaa, Sara
RA   Hinton, Jonathan
RA   Fahey, Ciara
RA   Fu, Bei-Yuan
RA   Swamy, Sajani
RA   Dalgliesh, Gillian L.
RA   Teh, Bin Tean
RA   Deloukas, Panos
RA   Yang, Feng-Tang
RA   Campbell, Peter J.
RA   Futreal, P. Andrew
RA   Stratton, Michael Rudolf
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=12702577;
RA   Saito-Ohara, Fumiko
RA   Imoto, Issei
RA   Inoue, Jun
RA   Hosoi, Hajime
RA   Nakagawara, Akira
RA   Sugimoto, Tohru
RA   Inazawa, Johji
RT   "PPM1D is a potential target for 17q gain in neuroblastoma.";
RL   Cancer Res. 63:1876-1883(2003).
//